| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Golden Compass | - | - | - | $2,714,379 | 110 | $3,735,217 | Dec 6 | Warner Bros. | false |
| 2 | Ratatouille | - | - | - | $1,486,746 | 102 | $9,756,656 | Aug 1 | Walt Disney Pictures | false |
| 3 | Bee Movie | - | - | - | $1,157,568 | 93 | $2,040,199 | Dec 12 | Universal Pictures International (UPI) | false |
| 4 | Enchanted | - | - | - | $1,145,115 | 96 | $2,014,722 | Nov 28 | Walt Disney Pictures | false |
| 5 | American Gangster | - | - | - | $826,930 | 58 | $2,555,668 | Nov 14 | Universal Pictures International (UPI) | false |
| 6 | Why Men Don't Listen and Women Can't Read Maps | - | - | - | $577,489 | 24 | $901,085 | Dec 6 | Rialto Distribution | false |
| 7 | I Am Legend | - | - | - | $566,324 | 96 | $3,174,297 | Dec 19 | Warner Bros. | false |
| 8 | Hitman | - | - | - | $550,173 | 30 | $801,277 | Dec 13 | 20th Century Fox International | false |
| 9 | Elizabeth: The Golden Age | - | - | - | $545,402 | 39 | $1,339,842 | Dec 19 | Universal Pictures International (UPI) | false |
| 10 | Alvin and the Chipmunks | - | - | - | $532,267 | 47 | $1,816,845 | Dec 19 | 20th Century Fox International | false |
| 11 | The Band's Visit | - | - | - | $453,045 | 19 | $1,037,500 | Dec 5 | Xenix Filmdistribution | false |
| 12 | Natale in crociera | - | - | - | $426,528 | 15 | $537,646 | Dec 14 | Morandini Film Distribution | false |
| 13 | Rabbit Without Ears | - | - | - | $383,982 | 25 | $2,439,642 | Dec 20 | Warner Bros. | false |
| 14 | The Heartbreak Kid | - | - | - | $279,765 | 62 | $1,626,412 | Nov 1 | Universal Pictures International (UPI) | false |
| 15 | Earth | - | - | - | $267,368 | 41 | $1,133,034 | Oct 10 | Frenetic Films | false |
| 16 | Atonement | - | - | - | $246,800 | 20 | $1,041,524 | Nov 8 | Universal Pictures International (UPI) | false |
| 17 | Aliens vs. Predator: Requiem | - | - | - | $243,558 | 49 | $698,541 | Dec 27 | 20th Century Fox International | false |
| 18 | Gone Baby Gone | - | - | - | $230,774 | 11 | $392,090 | Nov 29 | Walt Disney Pictures | false |
| 19 | Eastern Promises | - | - | - | $191,689 | 24 | $977,777 | Nov 7 | Ascot Elite Entertainment Group | false |
| 20 | The Fox and the Child | - | - | - | $189,592 | 30 | $426,275 | Dec 12 | Frenetic Films | false |
| 21 | I Now Pronounce You Chuck & Larry | - | - | - | $183,101 | 29 | $1,260,717 | Aug 29 | Universal Pictures International (UPI) | false |
| 22 | A Beautiful Wife | - | - | - | $177,530 | 9 | $260,068 | Dec 20 | Morandini Film Distribution | false |
| 23 | Lions for Lambs | - | - | - | $174,924 | 37 | $892,207 | Nov 8 | 20th Century Fox International | false |
| 24 | Beowulf | - | - | - | $141,109 | 76 | $686,002 | Nov 15 | Warner Bros. | false |
| 25 | Resident Evil: Extinction | - | - | - | $117,874 | 16 | $184,494 | Nov 29 | Rialto Distribution | false |
| 26 | The Three Investigators and the Secret of Skeleton Island | - | - | - | $107,941 | 62 | $451,601 | Nov 8 | Walt Disney Pictures | false |
| 27 | Animals in Love | - | - | - | $88,196 | 45 | $98,849 | Dec 19 | JMH Distribution | false |
| 28 | Michael Clayton | - | - | - | $71,629 | 20 | $1,096,760 | Oct 5 | Rialto Distribution | false |
| 29 | Free Rainer | - | - | - | $66,556 | 8 | $97,151 | Nov 29 | Pathé | false |
| 30 | The Secret of the Grain | - | - | - | $40,062 | 3 | $40,974 | Dec 12 | Pathé | false |
| 31 | My Blueberry Nights | - | - | - | $37,847 | 9 | $331,910 | Nov 28 | Frenetic Films | false |
| 32 | L'auberge rouge | - | - | - | $25,898 | 10 | $28,845 | Dec 5 | JMH Distribution | false |
| 33 | Go West: A Lucky Luke Adventure | - | - | - | $22,194 | 10 | $22,834 | Dec 5 | Pathé | false |
