Domestic Box Office For December 1980
| Rank | Release | Gross | Max Th | Opening | % of Total | Open Th | Open | Close | Distributor |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 9 to 5 | $103,290,500 | 910 | $3,966,832 | 3.8% | 910 | Dec 19 | - | 20th Century Fox |
| 2 | Stir Crazy | $101,300,000 | 813 | $8,691,886 | 8.6% | 813 | Dec 12 | - | Columbia Pictures |
| 3 | Any Which Way You Can | $70,687,344 | 1,541 | $8,024,663 | 11.4% | 1,541 | Dec 17 | - | Warner Bros. |
| 4 | Popeye | $49,823,037 | 901 | $6,310,520 | 12.7% | 901 | Dec 12 | - | Paramount Pictures |
| 5 | Seems Like Old Times | $43,995,918 | - | - | - | - | Dec 19 | - | Columbia Pictures |
| 6 | The Jazz Singer | $27,118,000 | - | - | - | - | Dec 19 | - | Universal Pictures |
| 7 | Flash Gordon | $27,107,960 | 823 | $3,934,030 | 14.5% | 823 | Dec 5 | - | Universal Pictures |
| 8 | Tess | $20,093,330 | - | - | - | - | Dec 12 | - | Columbia Pictures |
| 9 | Altered States | $19,853,892 | 3 | $174,650 | 0.9% | 3 | Dec 25 | - | Warner Bros. |
| 10 | First Family | $15,198,912 | 563 | $3,635,564 | 23.9% | 563 | Dec 25 | - | Warner Bros. |
| 11 | The Competition | $14,287,755 | 6 | $76,163 | 0.5% | 6 | Dec 3 | - | Columbia Pictures |
| 12 | The Mirror Crack'd | $11,000,000 | - | - | - | - | Dec 19 | - | Associated Film Distribution (AFD) |
| 13 | Tribute | $9,000,000 | - | - | - | - | Dec 14 | - | 20th Century Fox |
| 14 | The Formula | $8,894,289 | 477 | $842,985 | 9.5% | 477 | Dec 19 | - | Metro-Goldwyn-Mayer (MGM) |
