| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Kung Fu Panda 2 | - | - | - | $6,490,237 | 809 | $15,945,378 | Aug 24 | United International Pictures | false |
| 2 | Mr. Popper's Penguins | - | - | - | $3,465,037 | 277 | $3,972,634 | Aug 12 | 20th Century Fox International | false |
| 3 | Captain America: The First Avenger | - | - | - | $2,834,422 | 556 | $8,601,080 | Jul 22 | United International Pictures | false |
| 4 | Harry Potter and the Deathly Hallows: Part 2 | - | - | - | $2,568,745 | 1,008 | $29,775,040 | Jul 13 | Warner Bros. | false |
| 5 | Horrible Bosses | - | - | - | $1,890,346 | 330 | $2,987,850 | Aug 17 | Warner Bros. | false |
| 6 | Bridesmaids | - | - | - | $1,515,674 | 275 | $1,842,301 | Aug 19 | United International Pictures | false |
| 7 | Stan Helsing | - | - | - | $1,111,515 | 184 | $1,120,672 | Aug 17 | Eagle Pictures | false |
| 8 | Conan the Barbarian | - | - | - | $988,108 | 320 | $1,120,116 | Aug 18 | 01 Distribution | false |
| 9 | Tekken | - | - | - | $722,304 | 165 | $722,304 | Aug 5 | - | false |
| 10 | Cars 2 | - | - | - | $636,247 | 834 | $14,421,348 | Jun 22 | Walt Disney Pictures | false |
| 11 | Hanna | - | - | - | $575,887 | 231 | $567,320 | Aug 12 | Sony Pictures Releasing | false |
| 12 | Fright Night | - | - | - | $524,263 | 245 | $784,802 | Aug 26 | Walt Disney Pictures | false |
| 13 | Welcome to the South | - | - | - | $449,276 | 568 | $43,015,634 | Oct 1 | Medusa Distribuzione | false |
| 14 | The Mechanic | - | - | - | $359,115 | 125 | $690,772 | Aug 24 | 01 Distribution | false |
| 15 | Transformers: Dark of the Moon | - | - | - | $354,872 | 702 | $12,398,269 | Jul 1 | United International Pictures | false |
| 16 | Second Chance | - | - | - | $312,998 | 179 | $1,449,548 | Jul 13 | Moviemax | false |
| 17 | Diary of a Wimpy Kid | - | - | - | $286,168 | 100 | $533,730 | Jul 28 | 20th Century Fox International | false |
| 18 | Flypaper | - | - | - | $276,400 | 138 | $412,584 | Aug 26 | Eagle Pictures | false |
| 19 | The Women on the 6th Floor | - | - | - | $213,221 | 61 | $1,673,306 | Jun 10 | - | false |
| 20 | Green Lantern | - | - | - | $187,380 | 375 | $3,162,104 | Aug 31 | Warner Bros. | false |
| 21 | Diary of a Wimpy Kid: Rodrick Rules | - | - | - | $180,425 | 104 | $546,695 | Aug 5 | 20th Century Fox International | false |
| 22 | Come trovare nel modo giusto l'uomo sbagliato | - | - | - | $130,534 | 77 | $195,943 | Aug 26 | 20th Century Fox International | false |
| 23 | Grease 2010 Sing-a-long | - | - | - | $121,687 | 129 | $122,251 | Aug 12 | Nexo | false |
| 24 | War Games | - | - | - | $115,491 | 68 | $322,562 | Jul 22 | Bolero Film | false |
| 25 | This Is England 2011 Re-release | - | - | - | $85,333 | 28 | $304,710 | Aug 26 | - | false |
| 26 | Almeno tu nell'universo | - | - | - | $76,708 | 100 | $76,708 | Aug 12 | Lucky Red | false |
| 27 | Detective Dee: The Mystery of the Phantom Flame | - | - | - | $74,499 | 42 | $105,896 | Aug 26 | - | false |
| 28 | Zack and Miri Make a Porno | - | - | - | $42,365 | 151 | $630,524 | Jun 1 | - | false |
| 29 | The Kid with a Bike | - | - | - | $33,198 | 63 | $1,106,665 | May 18 | Lucky Red | false |
| 30 | No Place to Go 2011 Re-release | - | - | - | $21,962 | - | $36,227 | Aug 12 | - | false |
| 31 | Prom | - | - | - | $18,980 | 14 | $18,980 | Aug 19 | Walt Disney Pictures | false |
| 32 | In the Market | - | - | - | $18,135 | 4 | $68,871 | Aug 12 | - | false |
| 33 | The Conformist 2011 Re-release | - | - | - | $15,755 | 5 | $55,031 | Aug 26 | - | false |
| 34 | Student Services | - | - | - | $12,006 | 18 | $12,006 | Aug 26 | - | false |
| 35 | The Tree of Life | - | - | - | $7,679 | 181 | $3,863,901 | May 18 | 01 Distribution | false |
| 36 | Snow Flower and the Secret Fan | - | - | - | $7,558 | 111 | $550,573 | Jul 8 | Eagle Pictures | false |
| 37 | Red | - | - | - | $6,064 | 396 | $4,037,945 | May 11 | Medusa Distribuzione | false |
| 38 | We Have a Pope | - | - | - | $5,802 | 453 | $7,894,680 | Apr 15 | 01 Distribution | false |
| 39 | Season of the Witch | - | - | - | $4,083 | 349 | $4,383,131 | Jun 17 | Medusa Distribuzione | false |
| 40 | Escort in Love | - | - | - | $4,003 | 485 | $11,471,250 | Mar 16 | 01 Distribution | false |
| 41 | The Conspirator | - | - | - | $3,443 | 72 | $574,917 | Jun 22 | 01 Distribution | false |
| 42 | The Adjustment Bureau | - | - | - | $2,399 | 295 | $2,640,766 | Jun 17 | Universal Pictures International (UPI) | false |
| 43 | The King's Speech | - | - | - | $1,499 | 228 | $12,493,249 | Jan 28 | Eagle Pictures | false |
| 44 | Hereafter | - | - | - | $1,476 | 371 | $11,240,698 | Jan 5 | Warner Bros. | false |
| 45 | Barney's Version | - | - | - | $1,452 | 235 | $3,764,747 | Jan 14 | Medusa Distribuzione | false |
| 46 | Seraphine | - | - | - | $1,439 | 12 | $169,425 | Oct 22 | One Movie | false |
| 47 | Women Vs Men | - | - | - | $1,401 | 625 | $16,719,346 | Feb 4 | Medusa Distribuzione | false |
| 48 | Il diario di Matilde Manzoni | - | - | - | $1,398 | 1 | $21,416 | Sep 27 | - | false |
| 49 | Corpo Celeste 2011 Re-release | - | - | - | $1,341 | 23 | $306,413 | May 27 | - | false |
| 50 | Dancing Dreams | - | - | - | $1,299 | 2 | $1,299 | Aug 19 | - | false |
| 51 | Black Swan | - | - | - | $1,079 | 286 | $8,127,017 | Feb 18 | 20th Century Fox International | false |
| 52 | The Hunter | - | - | - | $1,074 | 5 | $21,652 | Jun 17 | Fandango | false |
| 53 | The Immature | - | - | - | $978 | 519 | $21,858,834 | Jan 21 | Medusa Distribuzione | false |
| 54 | In a Better World | - | - | - | $975 | 40 | $807,897 | Dec 10 | Teodora Film | false |
| 55 | X-Men: First Class | - | - | - | $942 | 522 | $3,982,424 | Jun 8 | 20th Century Fox International | false |
| 56 | The First Assignment | - | - | - | $927 | 21 | $260,294 | May 6 | Teodora Film | false |
| 57 | Vanishing on 7th Street | - | - | - | $901 | 13 | $46,957 | Jul 28 | One Movie | false |
| 58 | A Quiet Life | - | - | - | $890 | 164 | $2,021,470 | Nov 5 | 01 Distribution | false |
| 59 | Il pezzo mancante | - | - | - | $824 | 3 | $33,181 | Jun 17 | - | false |
