| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Inception | - | - | - | $202,535 | 5 | $504,666 | Jul 23 | Warner Bros. | false |
| 2 | Salt | - | - | - | $154,827 | 7 | $175,440 | Aug 11 | Sony Pictures Releasing | false |
| 3 | The Expendables | - | - | - | $134,273 | 4 | $263,958 | Aug 18 | - | false |
| 4 | The Karate Kid | - | - | - | $105,968 | 6 | $138,074 | Jul 28 | Sony Pictures Releasing | false |
| 5 | Shrek Forever After | - | - | - | $88,563 | 11 | $312,764 | Jul 14 | United International Pictures | false |
| 6 | The Sorcerer's Apprentice | - | - | - | $62,668 | 6 | $87,240 | Aug 6 | Walt Disney Pictures | false |
| 7 | The Last Airbender | - | - | - | $43,481 | 5 | $59,077 | Aug 13 | United International Pictures | false |
| 8 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $34,330 | 6 | $61,502 | Aug 18 | Warner Bros. | false |
| 9 | Toy Story 3 | - | - | - | $31,990 | 10 | $453,707 | Jun 18 | Walt Disney Pictures | false |
| 10 | Letters to Juliet | - | - | - | $25,676 | 4 | $50,816 | Aug 18 | - | false |
| 11 | Step Up 3D | - | - | - | $24,672 | 5 | $125,848 | Aug 25 | - | false |
| 12 | Knight and Day 2010 Re-release | - | - | - | $20,619 | 6 | $112,888 | Jul 7 | 20th Century Fox International | false |
| 13 | Vampires Suck | - | - | - | $14,264 | 3 | $21,865 | Aug 18 | 20th Century Fox International | false |
| 14 | Scott Pilgrim vs. the World | - | - | - | $13,953 | 3 | $54,265 | Aug 25 | United International Pictures | false |
| 15 | Grown Ups | - | - | - | $13,606 | 6 | $135,743 | Jun 24 | Sony Pictures Releasing | false |
| 16 | Predators | - | - | - | $11,476 | 4 | $67,080 | Jul 14 | 20th Century Fox International | false |
| 17 | Babies | - | - | - | $10,275 | 2 | $24,917 | Jul 21 | - | false |
| 18 | 22 Bullets | - | - | - | $9,010 | 1 | $11,336 | Aug 4 | - | false |
| 19 | The Ugly Duckling and Me! | - | - | - | $7,575 | 4 | $8,037 | Aug 6 | - | false |
| 20 | The Twilight Saga: Eclipse | - | - | - | $6,370 | 5 | $155,784 | Jul 2 | - | false |
| 21 | Killers | - | - | - | $3,279 | 4 | $77,318 | Jun 30 | - | false |
| 22 | The Human Centipede (First Sequence) | - | - | - | $3,041 | 1 | $9,632 | Aug 25 | - | false |
| 23 | Sex and the City 2 | - | - | - | $2,986 | 9 | $245,935 | Jun 4 | Warner Bros. | false |
