| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Inception | - | - | - | $2,155,939 | 138 | $3,144,672 | Aug 6 | Warner Bros. | false |
| 2 | Despicable Me | - | - | - | $1,795,686 | 145 | $297 | Apr 27 | Universal Pictures International (UPI) | false |
| 3 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $1,625,272 | 146 | $2,094,843 | Aug 13 | Warner Bros. | false |
| 4 | The Last Airbender | - | - | - | $965,004 | 185 | $3,408,130 | Aug 27 | United International Pictures | false |
| 5 | The Sorcerer's Apprentice | - | - | - | $845,364 | 116 | $2,953,007 | Jul 16 | Walt Disney Pictures | false |
| 6 | Grown Ups | - | - | - | $645,070 | 50 | $998,569 | Aug 6 | Sony Pictures Releasing | false |
| 7 | Shrek Forever After | - | - | - | $639,643 | 179 | $6,688,109 | Jul 9 | United International Pictures | false |
| 8 | Predators | - | - | - | $441,041 | 62 | $515,270 | Aug 13 | 20th Century Fox International | false |
| 9 | Salt | - | - | - | $298,021 | 65 | $823,455 | Jul 23 | Sony Pictures Releasing | false |
| 10 | Oceans | - | - | - | $243,579 | 37 | $548,608 | Aug 20 | Cine Colombia | false |
| 11 | Toy Story 3 | - | - | - | $96,540 | 254 | $10,637,930 | Jun 18 | Walt Disney Pictures | false |
| 12 | Green Zone 2010 Re-release | - | - | - | $69,099 | 25 | $131,978 | Aug 20 | United International Pictures | false |
| 13 | The Twilight Saga: Eclipse | - | - | - | $60,353 | 212 | $3,042,308 | Jun 30 | Cine Colombia | false |
| 14 | Knight and Day Original Release | - | - | - | $54,182 | 98 | $714,396 | Jul 16 | 20th Century Fox International | false |
| 15 | Cherry Blossoms | - | - | - | $35,288 | 7 | $123,621 | Jul 9 | Cine Colombia | false |
| 16 | Halloween II | - | - | - | $33,233 | 22 | $118,926 | Aug 27 | Cine Colombia | false |
| 17 | Eden Lake | - | - | - | $24,392 | 22 | $99,461 | Jul 23 | Cine Colombia | false |
| 18 | Kick-Ass | - | - | - | $20,361 | 32 | $20,361 | Aug 13 | United International Pictures | false |
| 19 | My Life in Ruins | - | - | - | $15,339 | 20 | $41,259 | Jul 30 | Cine Colombia | false |
| 20 | The Karate Kid | - | - | - | $10,094 | 80 | $1,559,943 | Jun 18 | Sony Pictures Releasing | false |
| 21 | Two Lovers | - | - | - | $6,128 | 13 | $55,980 | Jun 11 | Cine Colombia | false |
| 22 | A Nightmare on Elm Street | - | - | - | $2,213 | 94 | $1,406,599 | May 14 | Warner Bros. | false |
| 23 | The Back-up Plan | - | - | - | $1,971 | 40 | $378,155 | Jun 18 | Sony Pictures Releasing | false |
