| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Despicable Me | - | - | - | $10,244,257 | 387 | $13,743,913 | Aug 6 | Universal Pictures International (UPI) | false |
| 2 | Inception | - | - | - | $7,496,070 | 314 | $10,315,556 | Aug 6 | Warner Bros. | false |
| 3 | The Last Airbender | - | - | - | $5,132,949 | 279 | $9,653,005 | Aug 20 | Paramount Pictures International | false |
| 4 | Salt | - | - | - | $4,803,802 | 250 | $7,383,735 | Jul 30 | Sony Pictures Releasing | false |
| 5 | Shrek Forever After | - | - | - | $3,945,674 | 671 | $40,037,374 | Jul 9 | Paramount Pictures International | false |
| 6 | The Expendables | - | - | - | $3,788,963 | 179 | $4,739,155 | Aug 13 | - | false |
| 7 | The Sorcerer's Apprentice | - | - | - | $3,644,552 | 217 | $4,974,851 | Aug 13 | Walt Disney Pictures | false |
| 8 | The Karate Kid | - | - | - | $2,080,641 | 375 | $10,165,695 | Aug 27 | Sony Pictures Releasing | false |
| 9 | The Well Beloved One | - | - | - | $2,063,202 | 156 | $4,922,642 | Jul 23 | Walt Disney Pictures | false |
| 10 | The Twilight Saga: Eclipse | - | - | - | $1,214,280 | 818 | $30,499,010 | Jun 30 | Paris Filmes | false |
| 11 | Knight and Day Original Release | - | - | - | $1,122,293 | 316 | $8,663,633 | Jul 16 | 20th Century Fox International | false |
| 12 | Toy Story 3 | - | - | - | $679,851 | 485 | $23,613,926 | Jun 18 | Walt Disney Pictures | false |
| 13 | Killers | - | - | - | $529,597 | 123 | $2,513,311 | Aug 27 | - | false |
| 14 | 400 Against 1: A History of Organized Crime | - | - | - | $517,478 | 79 | $606,641 | Aug 6 | PlayArte Pictures | false |
| 15 | Predators | - | - | - | $384,136 | 170 | $2,017,215 | Jul 23 | 20th Century Fox International | false |
| 16 | Little Nicholas | - | - | - | $166,142 | 30 | $758,299 | Jul 2 | - | false |
| 17 | Coco Chanel & Igor Stravinsky | - | - | - | $142,613 | 20 | $228,930 | Aug 20 | - | false |
| 18 | 5x Favela: Now by Ourselves | - | - | - | $129,868 | 46 | $774,161 | Aug 27 | Sony Pictures Releasing | false |
| 19 | Mother and Child | - | - | - | $106,023 | 20 | $106,023 | Aug 13 | PlayArte Pictures | false |
| 20 | Ponyo | - | - | - | $96,379 | 43 | $145,841 | Jul 30 | PlayArte Pictures | false |
| 21 | Then She Found Me | - | - | - | $91,660 | 12 | $189,253 | Aug 6 | Europa Filmes | false |
| 22 | Death Proof 2010 Re-release | - | - | - | $70,808 | 47 | $452,647 | Jul 18 | PlayArte Pictures | false |
| 23 | The Crazies | - | - | - | $68,596 | 30 | $68,596 | Aug 20 | - | false |
| 24 | Whatever Works | - | - | - | $55,145 | 30 | $1,591,880 | Apr 30 | - | false |
| 25 | Prince of Persia: The Sands of Time | - | - | - | $51,090 | 363 | $10,124,446 | Jun 4 | Walt Disney Pictures | false |
| 26 | Honey | - | - | - | $50,769 | 12 | $50,769 | Aug 20 | Paris Filmes | false |
| 27 | The Back-up Plan | - | - | - | $44,935 | 163 | $3,377,721 | Jun 11 | Sony Pictures Releasing | false |
| 28 | Bright Star | - | - | - | $39,264 | 30 | $394,652 | Jun 25 | PlayArte Pictures | false |
| 29 | Letters to Juliet | - | - | - | $38,552 | 119 | $1,861,051 | Jun 11 | Paris Filmes | false |
| 30 | Cabeça a Prêmio | - | - | - | $38,264 | 19 | $38,264 | Aug 20 | Europa Filmes | false |
| 31 | I Love You Phillip Morris | - | - | - | $37,162 | 52 | $1,084,987 | Jun 4 | - | false |
| 32 | Alice in Wonderland | - | - | - | $22,463 | 567 | $28,360,362 | Apr 23 | Walt Disney Pictures | false |
| 33 | The Young Victoria | - | - | - | $21,657 | 37 | $511,100 | Jun 18 | Europa Filmes | false |
| 34 | The Two Deaths of Quincas Wateryell | - | - | - | $20,950 | 107 | $1,212,639 | May 21 | Walt Disney Pictures | false |
| 35 | The Best Things in the World | - | - | - | $16,853 | 152 | $1,214,499 | Apr 16 | Warner Bros. | false |
| 36 | The Secret in Their Eyes | - | - | - | $14,445 | 24 | $1,805,523 | Feb 26 | Europa Filmes | false |
| 37 | A Prophet | - | - | - | $13,869 | 6 | $170,212 | Jun 18 | Sony Pictures Releasing | false |
| 38 | Dear John | - | - | - | $11,514 | 33 | $258,261 | May 7 | Sony Pictures Releasing | false |
| 39 | The Imaginarium of Doctor Parnassus | - | - | - | $9,937 | 6 | $166,138 | May 7 | Sony Pictures Releasing | false |
| 40 | Ao: The Last Hunter | - | - | - | $7,245 | 5 | $14,167 | Jul 30 | - | false |
| 41 | Cold Souls | - | - | - | $3,850 | 13 | $81,750 | Jul 9 | Europa Filmes | false |
| 42 | Before the World Ends | - | - | - | $2,543 | 13 | $92,934 | May 14 | - | false |
| 43 | Chico Xavier | - | - | - | $1,629 | 340 | $17,229,064 | Apr 2 | Sony Pictures Releasing | false |
| 44 | The Last Song | - | - | - | $1,080 | 24 | $114,401 | Jun 11 | Walt Disney Pictures | false |
| 45 | The Twilight Saga: New Moon | - | - | - | $672 | 744 | $30,613,742 | Nov 20 | Paris Filmes | false |
