| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Up | - | - | - | $210,391 | 9 | $259,652 | Aug 7 | Walt Disney Pictures | false |
| 2 | Ice Age: Dawn of the Dinosaurs | - | - | - | $186,670 | 9 | $1,178,779 | Jul 3 | 20th Century Fox International | false |
| 3 | Inglourious Basterds | - | - | - | $116,434 | 5 | $289,951 | Aug 21 | United International Pictures | false |
| 4 | Harry Potter and the Half-Blood Prince | - | - | - | $106,402 | 6 | $216,589 | Jul 24 | Warner Bros. | false |
| 5 | District 9 | - | - | - | $57,264 | 2 | $63,741 | Aug 14 | Sony Pictures Releasing | false |
| 6 | Brüno | - | - | - | $53,034 | 3 | $232,777 | Jul 10 | - | false |
| 7 | The Taking of Pelham 123 | - | - | - | $34,538 | 3 | $34,538 | Jul 31 | Sony Pictures Releasing | false |
| 8 | The Hangover | - | - | - | $20,646 | 4 | $205,653 | Jun 19 | Warner Bros. | false |
| 9 | Spread | - | - | - | $20,050 | 1 | $48,073 | Aug 21 | - | false |
| 10 | Easy Virtue | - | - | - | $16,769 | 2 | $29,024 | Jul 24 | - | false |
| 11 | Fighting | - | - | - | $15,434 | 1 | $15,434 | Jul 31 | - | false |
| 12 | G.I. Joe: The Rise of Cobra | - | - | - | $15,107 | 5 | $34,353 | Aug 28 | United International Pictures | false |
| 13 | Two Lovers | - | - | - | $9,532 | 1 | $9,532 | Aug 21 | - | false |
| 14 | Public Enemies | - | - | - | $9,396 | 4 | $68,221 | Jul 10 | United International Pictures | false |
| 15 | Paul Blart: Mall Cop | - | - | - | $8,490 | 3 | $16,513 | Jul 24 | Sony Pictures Releasing | false |
| 16 | Dorothy Mills | - | - | - | $6,075 | 1 | $6,075 | Jul 31 | - | false |
| 17 | Transformers: Revenge of the Fallen | - | - | - | $546 | 5 | $125,346 | Jun 26 | United International Pictures | false |
