| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Chronicles of Narnia: Prince Caspian | - | - | - | $8,813,041 | 601 | $10,800,873 | Aug 14 | Walt Disney Pictures | false |
| 2 | The Dark Knight | - | - | - | $6,969,093 | 616 | $13,871,401 | Jul 23 | Warner Bros. | false |
| 3 | Kung Fu Panda | - | - | - | $6,957,422 | 669 | $22,037,818 | Aug 29 | Universal Pictures International (UPI) | false |
| 4 | Meet Dave | - | - | - | $1,787,573 | 307 | $2,361,245 | Aug 22 | 20th Century Fox International | false |
| 5 | Taken | - | - | - | $1,779,252 | 198 | $2,091,060 | Aug 14 | 20th Century Fox International | false |
| 6 | Grande, grosso e... Verdone | - | - | - | $1,737,437 | 703 | $21,860,130 | Mar 7 | Filmauro | false |
| 7 | Hellboy II: The Golden Army | - | - | - | $1,113,103 | 345 | $4,722,358 | Jul 16 | Universal Pictures International (UPI) | false |
| 8 | Shutter | - | - | - | $835,703 | 117 | $835,703 | Aug 8 | 20th Century Fox International | false |
| 9 | Shrooms | - | - | - | $832,322 | 111 | $1,143,622 | Aug 22 | Moviemax | false |
| 10 | Wanted | - | - | - | $585,986 | 393 | $6,197,505 | Jul 2 | Universal Pictures International (UPI) | false |
| 11 | Doomsday | - | - | - | $550,171 | 203 | $1,413,511 | Aug 29 | Medusa Distribuzione | false |
| 12 | The Flock | - | - | - | $535,488 | 71 | $564,027 | Aug 14 | 01 Distribution | false |
| 13 | Get Smart | - | - | - | $483,435 | 316 | $3,206,939 | Jul 9 | Warner Bros. | false |
| 14 | Un'estate al mare | - | - | - | $419,848 | 576 | $7,770,731 | Jun 27 | Medusa Distribuzione | false |
| 15 | Teeth | - | - | - | $365,674 | 114 | $394,820 | Aug 22 | Mediafilm | false |
| 16 | Gracie | - | - | - | $353,810 | 119 | $703,674 | Jul 18 | Moviemax | false |
| 17 | Heavy Petting | - | - | - | $350,217 | 149 | $406,362 | Aug 14 | Eagle Pictures | false |
| 18 | Untraceable | - | - | - | $338,143 | 56 | $353,014 | Aug 1 | 01 Distribution | false |
| 19 | Funny Games | - | - | - | $302,341 | 204 | $2,100,005 | Jul 11 | Lucky Red | false |
| 20 | Deception | - | - | - | $298,157 | 208 | $664,207 | Aug 29 | Mikado Film | false |
| 21 | Go Go Tales | - | - | - | $292,712 | 110 | $849,766 | Jun 20 | Mediafilm | false |
| 22 | Andersen. Zhizn bez lyubvi | - | - | - | $229,140 | 17 | $229,140 | Aug 1 | Medusa Distribuzione | false |
| 23 | Gomorrah | - | - | - | $185,837 | 441 | $17,665,830 | May 16 | 01 Distribution | false |
| 24 | The Love Guru | - | - | - | $143,434 | 48 | $143,434 | Aug 1 | Universal Pictures International (UPI) | false |
| 25 | Il Divo | - | - | - | $140,841 | 358 | $8,517,653 | May 28 | Lucky Red | false |
| 26 | Once | - | - | - | $99,924 | 35 | $746,500 | May 30 | Sacher Distribuzione | false |
| 27 | Silk | - | - | - | $85,202 | 197 | $1,615,449 | Oct 26 | Medusa Distribuzione | false |
| 28 | The Kite Runner | - | - | - | $79,022 | 371 | $12,730,140 | Mar 28 | Filmauro | false |
| 29 | The Deaths of Ian Stone | - | - | - | $75,378 | 117 | $644,924 | Jul 18 | Medusa Distribuzione | false |
| 30 | Fist of the North Star: The Legends of the True Savior: Legend of Raoh-Chapter of Death in Love 2008 Re-release | - | - | - | $74,805 | 56 | $26,568 | Jul 4 | Mikado Film | false |
| 31 | Forgetting Sarah Marshall | - | - | - | $73,175 | 100 | $151,549 | Aug 22 | United International Pictures | false |
| 32 | Indiana Jones and the Kingdom of the Crystal Skull | - | - | - | $64,769 | 689 | $18,982,360 | May 23 | Universal Pictures International (UPI) | false |
| 33 | Non pensarci | - | - | - | $48,333 | 222 | $2,239,655 | Apr 4 | 01 Distribution | false |
| 34 | The Incredible Hulk | - | - | - | $47,836 | 477 | $6,460,290 | Jun 18 | Universal Pictures International (UPI) | false |
| 35 | Tutta la vita davanti | - | - | - | $44,852 | 368 | $5,648,340 | Mar 28 | Medusa Distribuzione | false |
| 36 | In Bruges | - | - | - | $41,946 | 151 | $772,903 | May 16 | Mikado Film | false |
| 37 | Caramel | - | - | - | $41,584 | 50 | $2,301,033 | Dec 21 | Archibald | false |
| 38 | The Year My Parents Went on Vacation | - | - | - | $36,959 | 27 | $384,887 | Jun 6 | Lucky Red | false |
| 39 | P2 | - | - | - | $34,703 | 24 | $144,854 | Jul 25 | Eagle Pictures | false |
| 40 | The Band's Visit | - | - | - | $29,421 | 51 | $919,800 | Mar 21 | Mikado Film | false |
| 41 | The Rocker | - | - | - | $28,712 | 149 | $426,236 | Sep 19 | 20th Century Fox International | false |
| 42 | Irina Palm | - | - | - | $27,566 | 54 | $2,612,727 | Dec 7 | Teodora Film | false |
| 43 | The Girl by the Lake | - | - | - | $25,854 | 143 | $4,688,666 | Sep 14 | Medusa Distribuzione | false |
| 44 | Invincible 2008 Re-release | - | - | - | $23,062 | 3 | $30,473 | Jul 25 | Ripley's Film | false |
| 45 | One Man Up | - | - | - | $22,159 | 3 | $317,231 | Aug 31 | Key Films | false |
| 46 | Grace Is Gone | - | - | - | $22,037 | 11 | $22,037 | Aug 1 | 01 Distribution | false |
| 47 | Animanera | - | - | - | $20,937 | 34 | $43,106 | Aug 29 | Medusa Distribuzione | false |
| 48 | Leatherheads | - | - | - | $18,454 | 218 | $3,763,108 | Apr 11 | Universal Pictures International (UPI) | false |
| 49 | Don't Waste Your Time, Johnny! | - | - | - | $17,399 | 64 | $664,266 | Nov 30 | Medusa Distribuzione | false |
| 50 | Impy's Island | - | - | - | $17,350 | 131 | $177,467 | Jun 27 | Mediafilm | false |
| 51 | Juno | - | - | - | $17,336 | 239 | $3,352,339 | Apr 4 | 20th Century Fox International | false |
| 52 | Black House 2008 Re-release | - | - | - | $15,452 | 19 | $41,543 | Jul 25 | Ripley's Film | false |
| 53 | Eldorado | - | - | - | $15,065 | 17 | $41,639 | Aug 29 | Archibald | false |
| 54 | Mongol: The Rise of Genghis Khan | - | - | - | $14,485 | 137 | $1,325,000 | May 9 | BIM Distribuzione | false |
| 55 | 12 | - | - | - | $13,083 | 16 | $134,299 | Jun 27 | 01 Distribution | false |
| 56 | The Secret of the Grain | - | - | - | $12,366 | 79 | $2,875,013 | Jan 11 | Lucky Red | false |
| 57 | The Early Bird Catches the Worm | - | - | - | $11,925 | 253 | $1,550,893 | Feb 29 | Medusa Distribuzione | false |
| 58 | The Comebacks | - | - | - | $10,032 | 11 | $10,032 | Aug 1 | 20th Century Fox International | false |
| 59 | No Country for Old Men | - | - | - | $8,294 | 308 | $8,979,650 | Feb 22 | Universal Pictures International (UPI) | false |
| 60 | War | - | - | - | $6,137 | 49 | $100,103 | Jul 18 | 01 Distribution | false |
| 61 | Before the Devil Knows You're Dead | - | - | - | $4,950 | 277 | $4,648,889 | Mar 14 | Medusa Distribuzione | false |
| 62 | The Rest of the Night 2008 Re-release | - | - | - | $4,923 | 61 | $282,009 | Jun 11 | 01 Distribution | false |
| 63 | The Chronicles of Narnia: The Lion, the Witch and the Wardrobe | - | - | - | $4,308 | 490 | $21,649,934 | Dec 21 | Buena Vista International | false |
| 64 | Postal | - | - | - | $3,980 | 12 | $3,980 | Aug 29 | One Movie | false |
| 65 | Things We Lost in the Fire | - | - | - | $3,949 | 97 | $414,156 | Jun 12 | Teodora Film | false |
| 66 | Days and Clouds | - | - | - | $3,831 | 214 | $6,010,383 | Oct 26 | Warner Bros. | false |
| 67 | Then She Found Me | - | - | - | $3,346 | 142 | $940,111 | Jun 6 | Medusa Distribuzione | false |
| 68 | Nelle tue mani | - | - | - | $3,105 | 18 | $111,266 | Mar 14 | Teodora Film | false |
| 69 | Animals in Love | - | - | - | $2,907 | 11 | $2,907 | Aug 22 | Mikado Film | false |
| 70 | Il dolce e l'amaro | - | - | - | $2,602 | 243 | $1,445,130 | Sep 7 | Medusa Distribuzione | false |
| 71 | Iron Man | - | - | - | $2,552 | 509 | $10,809,921 | May 1 | Universal Pictures International (UPI) | false |
| 72 | Across the Universe | - | - | - | $2,491 | 77 | $1,227,260 | Nov 23 | Sony Pictures Releasing | false |
| 73 | The Right Distance | - | - | - | $2,304 | 102 | $1,495,120 | Oct 19 | 01 Distribution | false |
| 74 | The Bucket List | - | - | - | $2,286 | 243 | $2,820,300 | Jan 25 | Warner Bros. | false |
| 75 | American Gangster | - | - | - | $2,203 | 457 | $15,520,131 | Jan 18 | Universal Pictures International (UPI) | false |
| 76 | Odette Toulemonde | - | - | - | $2,115 | 26 | $415,310 | Mar 7 | Warner Bros. | false |
| 77 | The Zone | - | - | - | $2,044 | 27 | $312,516 | Apr 4 | Sacher Distribuzione | false |
| 78 | The Counterfeiters | - | - | - | $2,039 | 21 | $349,800 | Jan 25 | Lady Film | false |
| 79 | The Demons of St. Petersburg | - | - | - | $1,863 | 110 | $1,409,678 | Apr 24 | 01 Distribution | false |
| 80 | Quiet Chaos | - | - | - | $1,810 | 384 | $9,204,569 | Feb 8 | 01 Distribution | false |
| 81 | Franchesca Page | - | - | - | $1,807 | 4 | $6,347 | Aug 22 | - | false |
| 82 | Charlie Wilson's War | - | - | - | $1,737 | 247 | $3,261,378 | Feb 8 | Universal Pictures International (UPI) | false |
| 83 | The Night of the Sunflowers | - | - | - | $1,731 | 11 | $67,192 | Jun 13 | Istituto Luce | false |
| 84 | Good Morning Heartache | - | - | - | $1,611 | 79 | $278,471 | Apr 11 | Medusa Distribuzione | false |
| 85 | Ho ammazzato Berlusconi | - | - | - | $1,392 | 4 | $77,794 | Jun 20 | Independent Films | false |
| 86 | 10 Items or Less | - | - | - | $1,366 | 35 | $226,695 | Apr 18 | DNC Entertainment | false |
