| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Cars | - | - | - | $7,513,504 | 637 | $16,456,342 | Aug 23 | Buena Vista International | false |
| 2 | Garfield: A Tail of Two Kitties | - | - | - | $3,132,261 | 312 | $4,838,072 | Aug 18 | 20th Century Fox International | false |
| 3 | Lucky Number Slevin | - | - | - | $1,991,641 | 304 | $4,486,090 | Aug 18 | Moviemax | false |
| 4 | Domino | - | - | - | $1,230,869 | 254 | $1,275,082 | Aug 18 | Eagle Pictures | false |
| 5 | The Fast and the Furious: Tokyo Drift | - | - | - | $1,105,725 | 195 | $4,389,074 | Jul 14 | United International Pictures | false |
| 6 | The Hills Have Eyes | - | - | - | $886,316 | 249 | $1,589,032 | Aug 25 | 20th Century Fox International | false |
| 7 | See No Evil | - | - | - | $779,316 | 146 | $1,023,761 | Jul 28 | Mediafilm | false |
| 8 | United 93 | - | - | - | $777,819 | 202 | $3,190,330 | Jul 6 | United International Pictures | false |
| 9 | The Man | - | - | - | $703,960 | 147 | $703,960 | Aug 11 | Eagle Pictures | false |
| 10 | The Da Vinci Code | - | - | - | $623,863 | 910 | $39,197,477 | May 19 | Sony Pictures Releasing | false |
| 11 | More Ants in the Pants 2006 Re-release | - | - | - | $520,745 | 70 | $520,745 | Aug 4 | Mediafilm | false |
| 12 | Silent Hill | - | - | - | $515,449 | 304 | $3,530,412 | Jul 7 | Eagle Pictures | false |
| 13 | Little Man | - | - | - | $349,365 | 109 | $662,306 | Aug 25 | Sony Pictures Releasing | false |
| 14 | Volver | - | - | - | $331,265 | 309 | $8,641,208 | May 19 | Warner Bros. | false |
| 15 | Notte prima degli esami | - | - | - | $279,854 | 327 | $15,905,030 | Feb 17 | 01 Distribution | false |
| 16 | The Lake House | - | - | - | $214,931 | 186 | $1,649,852 | Jun 23 | Warner Bros. | false |
| 17 | La notte del mio primo amore | - | - | - | $207,541 | 98 | $207,541 | Aug 11 | Mediafilm | false |
| 18 | C.R.A.Z.Y. | - | - | - | $122,032 | 80 | $166,162 | Aug 25 | Istituto Luce | false |
| 19 | Freedomland | - | - | - | $115,820 | 99 | $449,078 | Jul 14 | Sony Pictures Releasing | false |
| 20 | A Prairie Home Companion | - | - | - | $106,251 | 142 | $1,686,150 | Jun 1 | Medusa Distribuzione | false |
| 21 | Time | - | - | - | $97,765 | 36 | $207,847 | Aug 25 | Mikado Film | false |
| 22 | The Dark Sea | - | - | - | $97,484 | 30 | $170,998 | Aug 25 | 01 Distribution | false |
| 23 | Just My Luck | - | - | - | $90,591 | 38 | $338,776 | Jul 7 | 20th Century Fox International | false |
| 24 | Vita Smeralda | - | - | - | $77,617 | 113 | $707,659 | Jul 14 | Medusa Distribuzione | false |
| 25 | Date Movie | - | - | - | $70,079 | 221 | $1,883,254 | Jun 23 | 20th Century Fox International | false |
| 26 | La cura del gorilla | - | - | - | $68,154 | 154 | $760,249 | Feb 3 | Warner Bros. | false |
| 27 | 4-4-2 - Il gioco più bello del mondo | - | - | - | $62,285 | 101 | $452,097 | May 19 | Medusa Distribuzione | false |
| 28 | Casshern 2006 Re-release | - | - | - | $49,976 | 48 | $282,888 | Jul 14 | Time Code | false |
| 29 | Ghost in the Shell 2: Innocence | - | - | - | $38,117 | 31 | $38,117 | Aug 4 | Eagle Pictures | false |
| 30 | Alien Autopsy | - | - | - | $33,892 | 56 | $33,892 | Aug 25 | Warner Bros. | false |
| 31 | Pulse 2005 Re-release | - | - | - | $33,363 | 41 | $33,363 | Aug 18 | Mediafilm | false |
| 32 | Inside Man | - | - | - | $24,289 | 301 | $9,116,281 | Apr 7 | United International Pictures | false |
| 33 | The Sentinel | - | - | - | $11,989 | 211 | $1,148,607 | Jun 23 | 01 Distribution | false |
| 34 | Orchestra Seats | - | - | - | $9,021 | 61 | $431,631 | Jun 16 | DNC Entertainment | false |
