| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: Dead Man's Chest | - | - | - | $32,218,802 | 787 | $36,609,592 | Aug 11 | Buena Vista International | false |
| 2 | Poseidon | - | - | - | $5,002,774 | 429 | $8,550,398 | Jul 28 | Warner Bros. | false |
| 3 | Bandidas | - | - | - | $4,192,874 | 250 | $4,370,015 | Aug 4 | 20th Century Fox International | false |
| 4 | Garfield: A Tail of Two Kitties | - | - | - | $3,511,519 | 415 | $8,584,642 | Aug 25 | 20th Century Fox International | false |
| 5 | Cars | - | - | - | $3,197,038 | 556 | $16,342,337 | Jul 7 | Buena Vista International | false |
| 6 | The Sentinel | - | - | - | $2,949,761 | 285 | $6,255,372 | Jul 21 | 20th Century Fox International | false |
| 7 | Silent Hill | - | - | - | $2,913,907 | 180 | $4,403,940 | Jul 28 | United International Pictures | false |
| 8 | Lady in the Water | - | - | - | $2,768,440 | 328 | $5,728,908 | Aug 25 | Warner Bros. | false |
| 9 | An American Haunting | - | - | - | $2,431,032 | 242 | $3,103,045 | Aug 18 | DeAPlaneta | false |
| 10 | Superman Returns | - | - | - | $1,954,017 | 560 | $11,721,291 | Jul 12 | Warner Bros. | false |
| 11 | The Fast and the Furious: Tokyo Drift | - | - | - | $1,525,489 | 225 | $4,738,552 | Jul 21 | United International Pictures | false |
| 12 | United 93 | - | - | - | $1,254,706 | 134 | $3,579,543 | Aug 23 | United International Pictures | false |
| 13 | The Shaggy Dog | - | - | - | $1,147,767 | 350 | $2,795,617 | Jul 21 | Buena Vista International | false |
| 14 | Open Water 2: Adrift | - | - | - | $938,770 | 153 | $1,034,542 | Aug 18 | On Pictures | false |
| 15 | Curious George | - | - | - | $893,763 | 189 | $1,054,847 | Aug 4 | United International Pictures | false |
| 16 | The Da Vinci Code | - | - | - | $711,749 | 752 | $34,543,406 | May 19 | Sony Pictures Releasing | false |
| 17 | The Near East | - | - | - | $627,593 | 106 | $775,228 | Aug 18 | 20th Century Fox International | false |
| 18 | The Breed | - | - | - | $625,095 | 178 | $625,095 | Aug 4 | New World Pictures | false |
| 19 | The Tiger and the Snow | - | - | - | $568,028 | 160 | $2,590,529 | Jul 7 | 20th Century Fox International | false |
| 20 | Talladega Nights: The Ballad of Ricky Bobby | - | - | - | $543,723 | 250 | $612,801 | Aug 18 | Sony Pictures Releasing | false |
| 21 | Nacho Libre | - | - | - | $480,095 | 152 | $560,650 | Aug 18 | United International Pictures | false |
| 22 | C.R.A.Z.Y. | - | - | - | $429,990 | 30 | $622,932 | Aug 4 | Golem Distribución | false |
| 23 | Waiting... | - | - | - | $423,879 | 175 | $527,905 | Aug 4 | Aurum Films | false |
| 24 | Unhitched | - | - | - | $392,925 | 148 | $392,925 | Aug 18 | Aurum Films | false |
| 25 | The Lake House | - | - | - | $382,116 | 227 | $3,922,500 | Jun 30 | Warner Bros. | false |
| 26 | The Night of the Sunflowers | - | - | - | $367,541 | 90 | $1,123,189 | Aug 25 | Alta Films | false |
| 27 | Lord of War | - | - | - | $365,357 | 200 | $3,543,503 | Jun 30 | Sony Pictures Releasing | false |
| 28 | Blue Days | - | - | - | $263,368 | 74 | $263,368 | Aug 11 | Alta Films | false |
| 29 | Sex Crazy | - | - | - | $260,831 | 118 | $327,490 | Aug 25 | Filmax | false |
| 30 | Domino | - | - | - | $258,800 | 264 | $1,192,373 | Jul 21 | Aurum Films | false |
| 31 | Los mánagers | - | - | - | $220,669 | 215 | $2,498,903 | Jul 7 | Filmax | false |
| 32 | Summer in Berlin | - | - | - | $178,340 | 40 | $434,761 | Aug 4 | Alta Films | false |
| 33 | Breakfast on Pluto | - | - | - | $135,202 | 49 | $408,071 | Aug 25 | Vértigo Films | false |
| 34 | Sky Fighters | - | - | - | $105,243 | 102 | $105,243 | Aug 25 | TriPictures | false |
| 35 | The Great Challenge | - | - | - | $53,269 | 68 | $53,269 | Aug 4 | Manga Entertainment | false |
| 36 | Secret Agents 2006 Re-release | - | - | - | $41,047 | 50 | $41,047 | Aug 11 | 20th Century Fox International | false |
