| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: Dead Man's Chest | - | - | - | $1,684,335 | 115 | $4,409,190 | Jul 20 | Buena Vista International | false |
| 2 | Bañeros III, todopoderosos | - | - | - | $997,270 | 105 | $3,018,987 | Jul 13 | Argentina Sono Film S.A.C.I. | false |
| 3 | Over the Hedge | - | - | - | $805,035 | 145 | $2,652,731 | Jul 13 | United International Pictures | false |
| 4 | The Break-Up | - | - | - | $724,918 | 40 | $960,763 | Aug 3 | United International Pictures | false |
| 5 | El ratón Pérez | - | - | - | $678,199 | 110 | $2,390,912 | Jul 6 | Buena Vista International | false |
| 6 | Patoruzito: The Great Adventure | - | - | - | $675,424 | 141 | $1,427,293 | Jun 29 | Warner Bros. | false |
| 7 | Volver | - | - | - | $500,528 | 31 | $956,119 | Aug 10 | 20th Century Fox International | false |
| 8 | 16 Blocks | - | - | - | $371,131 | 31 | $550,731 | Aug 10 | Distribution Company | false |
| 9 | Cars | - | - | - | $359,558 | 127 | $3,100,679 | Jun 29 | Buena Vista International | false |
| 10 | Monster House | - | - | - | $332,268 | 48 | $555,676 | Aug 10 | Sony Pictures Releasing | false |
| 11 | The Hands | - | - | - | $329,845 | 48 | $513,709 | Aug 10 | Primer Plano Film Group | false |
| 12 | Superman Returns | - | - | - | $325,167 | 132 | $1,560,704 | Jul 13 | Warner Bros. | false |
| 13 | The Sentinel | - | - | - | $320,694 | 41 | $567,876 | Aug 17 | 20th Century Fox International | false |
| 14 | Click | - | - | - | $249,433 | 31 | $710,028 | Aug 17 | Sony Pictures Releasing | false |
| 15 | Prime | - | - | - | $181,053 | 28 | $1,310,973 | May 25 | Distribution Company | false |
| 16 | Garfield: A Tail of Two Kitties | - | - | - | $167,351 | 77 | $844,279 | Jul 6 | 20th Century Fox International | false |
| 17 | The Fast and the Furious: Tokyo Drift | - | - | - | $162,126 | 30 | $300,714 | Aug 17 | United International Pictures | false |
| 18 | Premonition | - | - | - | $124,244 | 11 | $161,442 | Jul 27 | Pachamama Cine | false |
| 19 | Lady in the Water | - | - | - | $107,859 | 25 | $399,003 | Aug 24 | Warner Bros. | false |
| 20 | The Ant Bully | - | - | - | $102,331 | 34 | $179,878 | Aug 17 | Warner Bros. | false |
| 21 | The White Countess | - | - | - | $68,699 | 10 | $105,107 | Aug 17 | Alfa Films | false |
| 22 | Comedy of Power | - | - | - | $63,852 | 14 | $188,654 | Jul 20 | Alfa Films | false |
| 23 | Live and Become | - | - | - | $51,623 | 6 | $256,234 | Jun 15 | Distribution Company | false |
| 24 | Open Water 2: Adrift | - | - | - | $41,608 | 31 | $59,720 | Aug 24 | Alfa Films | false |
| 25 | Poseidon | - | - | - | $25,817 | 76 | $1,414,063 | Jun 15 | Warner Bros. | false |
| 26 | The Libertine | - | - | - | $25,115 | 18 | $153,513 | Jun 22 | Distribution Company | false |
| 27 | She's the Man | - | - | - | $25,005 | 15 | $45,215 | Jul 27 | Distribution Company | false |
| 28 | Sunday Lunch 2006 Re-release | - | - | - | $20,412 | 9 | $113,052 | Jun 29 | CDI Films | false |
| 29 | My Summer of Love | - | - | - | $14,856 | 12 | $43,786 | Jul 27 | Alfa Films | false |
| 30 | Walk on Water | - | - | - | $13,319 | 7 | $13,319 | Aug 24 | CDI Films | false |
| 31 | Curious George | - | - | - | $12,519 | 30 | $29,445 | Aug 10 | United International Pictures | false |
| 32 | La vita che vorrei 2006 Re-release | - | - | - | $9,510 | 6 | $20,752 | Jul 27 | Telexcel | false |
| 33 | The Beat That My Heart Skipped 2005 Re-release | - | - | - | $9,194 | 15 | $257,104 | Jun 15 | Alfa Films | false |
