| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Titanic 2012 3D Release | - | - | - | $10,394,763 | 357 | $9,847,064 | Apr 6 | 20th Century Fox International | false |
| 2 | To Rome with Love | - | - | - | $7,595,442 | 603 | $9,565,012 | Apr 20 | Medusa Distribuzione | false |
| 3 | The Avengers | - | - | - | $6,372,395 | 679 | $22,012,517 | Apr 25 | Walt Disney Pictures | false |
| 4 | Mirror Mirror | - | - | - | $6,323,999 | 387 | $6,571,936 | Apr 4 | 01 Distribution | false |
| 5 | Battleship | - | - | - | $5,551,710 | 420 | $5,747,869 | Apr 12 | United International Pictures | false |
| 6 | The Intouchables | - | - | - | $4,483,807 | 417 | $19,385,193 | Feb 23 | Medusa Distribuzione | false |
| 7 | Wrath of the Titans | - | - | - | $3,796,324 | 350 | $5,447,003 | Mar 29 | Warner Bros. | false |
| 8 | The Pirates! Band of Misfits | - | - | - | $3,029,750 | 417 | $3,208,545 | Apr 4 | Sony Pictures Releasing | false |
| 9 | Buona giornata! | - | - | - | $2,663,853 | 440 | $3,927,883 | Mar 29 | Medusa Distribuzione | false |
| 10 | Act of Valor | - | - | - | $2,630,081 | 214 | $2,907,547 | Apr 4 | - | false |
| 11 | Diaz: Don't Clean Up This Blood | - | - | - | $2,169,070 | 243 | $2,558,925 | Apr 12 | Fandango | false |
| 12 | Piazza Fontana: The Italian Conspiracy | - | - | - | $1,884,109 | 252 | $2,574,171 | Mar 29 | 01 Distribution | false |
| 13 | Bel Ami | - | - | - | $1,399,855 | 254 | $1,542,099 | Apr 12 | 01 Distribution | false |
| 14 | StreetDance 2 2012 Re-release | - | - | - | $1,376,043 | 251 | $1,718,734 | Apr 20 | Eagle Pictures | false |
| 15 | The Raven | - | - | - | $1,000,055 | 278 | $2,622,620 | Mar 23 | Eagle Pictures | false |
| 16 | È nata una star? | - | - | - | $953,909 | 424 | $3,695,736 | Mar 23 | Warner Bros. | false |
| 17 | Little White Lies | - | - | - | $914,396 | 89 | $1,079,098 | Apr 6 | Lucky Red | false |
| 18 | Ghost Rider: Spirit of Vengeance | - | - | - | $800,626 | 330 | $3,731,609 | Mar 23 | Medusa Distribuzione | false |
| 19 | The Lucky One | - | - | - | $678,079 | 281 | $1,948,392 | Apr 25 | Warner Bros. | false |
| 20 | The Best Exotic Marigold Hotel | - | - | - | $664,110 | 132 | $1,110,398 | Mar 29 | 20th Century Fox International | false |
| 21 | Cherry on the Cake | - | - | - | $627,137 | 50 | $1,094,191 | Apr 12 | Bolero Film | false |
| 22 | This Means War | - | - | - | $517,437 | 167 | $560,455 | Apr 20 | 20th Century Fox International | false |
| 23 | The Rum Diary | - | - | - | $477,891 | 264 | $1,439,166 | Apr 24 | 01 Distribution | false |
| 24 | The First Man | - | - | - | $460,968 | 76 | $954,811 | Apr 20 | 01 Distribution | false |
| 25 | Chicken with Plums | - | - | - | $378,662 | 41 | $541,904 | Apr 6 | Officine UBU | false |
| 26 | My Worst Nightmare | - | - | - | $352,061 | 82 | $620,827 | Mar 29 | BIM Distribuzione | false |
| 27 | A Magnificent Haunting | - | - | - | $351,929 | 444 | $3,950,054 | Mar 15 | 01 Distribution | false |
| 28 | Before Anything Else | - | - | - | $220,641 | 129 | $243,714 | Apr 4 | Eagle Pictures | false |
| 29 | Castle in the Sky 2012 Re-release | - | - | - | $173,987 | 143 | $725,189 | Apr 25 | Lucky Red | false |
| 30 | The Lady | - | - | - | $131,879 | 75 | $458,943 | Mar 23 | - | false |
| 31 | Chinese Take-Away | - | - | - | $126,732 | 29 | $367,010 | Mar 23 | - | false |
| 32 | Paranormal Xperience 3D | - | - | - | $125,298 | 109 | $259,087 | Mar 29 | Moviemax | false |
| 33 | Good as You | - | - | - | $121,548 | 46 | $123,536 | Apr 6 | - | false |
| 34 | Hunger 2012 Re-release | - | - | - | $101,716 | 45 | $397,707 | Apr 27 | BIM Distribuzione | false |
| 35 | Poker Generation | - | - | - | $90,057 | 66 | $90,057 | Apr 12 | - | false |
| 36 | Caesar Must Die | - | - | - | $80,341 | 41 | $961,469 | Mar 1 | Sacher Distribuzione | false |
| 37 | The Mill and the Cross | - | - | - | $65,683 | 11 | $206,470 | Mar 29 | - | false |
| 38 | Madang Amtark | - | - | - | $46,297 | 99 | $85,760 | Apr 20 | - | false |
| 39 | 17 Girls | - | - | - | $43,209 | 36 | $190,037 | Mar 16 | Teodora Film | false |
| 40 | A Simple Life | - | - | - | $23,769 | 34 | $296,212 | Mar 8 | - | false |
| 41 | The Devil Inside | - | - | - | $23,430 | 254 | $2,769,289 | Mar 15 | United International Pictures | false |
| 42 | A Flat for Three | - | - | - | $11,359 | 609 | $11,398,541 | Mar 1 | Filmauro | false |
| 43 | Hysteria | - | - | - | $8,566 | 141 | $1,388,235 | Feb 23 | BIM Distribuzione | false |
| 44 | Cave of Forgotten Dreams | - | - | - | $7,006 | 2 | $25,100 | Mar 8 | DIA Distributori Indipendenti | false |
| 45 | The Help | - | - | - | $6,479 | 188 | $1,568,200 | Jan 19 | Walt Disney Pictures | false |
| 46 | Dolphin Tale | - | - | - | $2,171 | 216 | $1,263,486 | Jan 12 | Warner Bros. | false |
| 47 | Welcome to the North | - | - | - | $1,860 | 854 | $33,498,625 | Jan 17 | Medusa Distribuzione | false |
| 48 | War Horse | - | - | - | $1,664 | 280 | $1,438,517 | Feb 16 | Walt Disney Pictures | false |
| 49 | George Harrison: Living in the Material World | - | - | - | $1,552 | 1 | $1,552 | Apr 19 | Nexo Digital | false |
| 50 | Quijote | - | - | - | $1,331 | 1 | $1,331 | Apr 6 | - | false |
| 51 | Haywire | - | - | - | $1,235 | 206 | $1,225,522 | Feb 23 | Moviemax | false |
| 52 | The Vanishing of Pato | - | - | - | $1,162 | 21 | $156,631 | Feb 23 | - | false |
| 53 | Someday This Pain Will Be Useful to You | - | - | - | $1,079 | 201 | $666,922 | Feb 23 | 01 Distribution | false |
| 54 | 10 Rules for Falling in Love | - | - | - | $695 | 236 | $1,050,875 | Mar 15 | Lucky Red | false |
| 55 | Big Miracle | - | - | - | $554 | 110 | $132,057 | Feb 23 | Universal Pictures International (UPI) | false |
| 56 | The Ides of March | - | - | - | $528 | 254 | $5,217,138 | Dec 16 | 01 Distribution | false |
| 57 | Mare chiuso | - | - | - | $472 | 2 | $16,779 | Mar 15 | - | false |
| 58 | Non me lo dire | - | - | - | $281 | 60 | $382,931 | Mar 15 | Bolero Film | false |
| 59 | The Artist | - | - | - | $212 | 127 | $3,528,704 | Dec 8 | BIM Distribuzione | false |
