| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Rio | - | - | - | $2,237,539 | 94 | $2,942,794 | Apr 8 | NuMetro Distribution | false |
| 2 | Just Go with It | - | - | - | $1,192,009 | 66 | $2,534,937 | Mar 18 | Ster-Kinekor Pictures | false |
| 3 | No Strings Attached | - | - | - | $900,991 | 55 | $1,160,279 | Apr 1 | United International Pictures | false |
| 4 | Hop | - | - | - | $868,505 | 77 | $1,004,056 | Apr 1 | United International Pictures | false |
| 5 | Unknown | - | - | - | $731,234 | 50 | $974,313 | Apr 8 | NuMetro Distribution | false |
| 6 | Gnomeo & Juliet | - | - | - | $707,813 | 83 | $1,229,164 | Mar 25 | Ster-Kinekor Pictures | false |
| 7 | Rango | - | - | - | $657,460 | 76 | $1,408,931 | Mar 18 | United International Pictures | false |
| 8 | Limitless | - | - | - | $618,749 | 50 | $968,463 | Apr 15 | NuMetro Distribution | false |
| 9 | I Am Number Four | - | - | - | $431,319 | 69 | $728,291 | Mar 25 | Ster-Kinekor Pictures | false |
| 10 | The Mechanic | - | - | - | $343,899 | 48 | $658,268 | Apr 1 | - | false |
| 11 | Water for Elephants | - | - | - | $316,172 | 41 | $426,138 | Apr 15 | NuMetro Distribution | false |
| 12 | The King's Speech | - | - | - | $230,327 | 25 | $1,392,993 | Feb 11 | Ster-Kinekor Pictures | false |
| 13 | Hall Pass | - | - | - | $208,550 | 60 | $424,450 | Mar 25 | NuMetro Distribution | false |
| 14 | Big Mommas: Like Father, Like Son | - | - | - | $204,336 | 64 | $1,352,084 | Feb 25 | NuMetro Distribution | false |
| 15 | Red Riding Hood | - | - | - | $156,742 | 61 | $674,904 | Mar 18 | NuMetro Distribution | false |
| 16 | Sucker Punch | - | - | - | $153,991 | 30 | $186,626 | Apr 22 | NuMetro Distribution | false |
| 17 | Paradise Stop | - | - | - | $149,489 | 55 | $303,702 | Mar 25 | - | false |
| 18 | The Eagle | - | - | - | $147,268 | 40 | $147,268 | Apr 8 | Ster-Kinekor Pictures | false |
| 19 | Mars Needs Moms | - | - | - | $132,892 | 24 | $177,128 | Apr 22 | Ster-Kinekor Pictures | false |
| 20 | The Roommate | - | - | - | $102,349 | 15 | $130,932 | Apr 15 | Ster-Kinekor Pictures | false |
| 21 | Tangled | - | - | - | $89,207 | 88 | $3,090,371 | Jan 28 | Ster-Kinekor Pictures | false |
| 22 | Tomorrow, When the War Began | - | - | - | $74,760 | 38 | $77,996 | Apr 15 | United International Pictures | false |
| 23 | Superhelde | - | - | - | $70,932 | 38 | $89,012 | Apr 22 | Ster-Kinekor Pictures | false |
| 24 | Barney's Version | - | - | - | $41,280 | 7 | $41,280 | Apr 8 | NuMetro Distribution | false |
| 25 | True Grit | - | - | - | $32,414 | 12 | $200,198 | Feb 18 | United International Pictures | false |
| 26 | Rabbit Hole | - | - | - | $26,903 | 7 | $26,903 | Apr 1 | NuMetro Distribution | false |
| 27 | Justin Bieber: Never Say Never | - | - | - | $23,758 | 47 | $250,849 | Mar 11 | United International Pictures | false |
| 28 | Dum Maaro Dum | - | - | - | $16,839 | 5 | $16,839 | Apr 22 | NuMetro Distribution | false |
| 29 | Somewhere | - | - | - | $16,311 | 6 | $16,311 | Apr 8 | Ster-Kinekor Pictures | false |
| 30 | Game | - | - | - | $15,817 | 7 | $15,817 | Apr 1 | NuMetro Distribution | false |
| 31 | The Dilemma | - | - | - | $15,689 | 42 | $324,138 | Mar 4 | NuMetro Distribution | false |
| 32 | Black Swan | - | - | - | $14,216 | 25 | $758,581 | Feb 4 | NuMetro Distribution | false |
| 33 | The Rite | - | - | - | $9,137 | 25 | $172,448 | Mar 11 | NuMetro Distribution | false |
| 34 | Another Year | - | - | - | $8,659 | 3 | $62,237 | Mar 11 | - | false |
| 35 | Never Let Me Go | - | - | - | $7,961 | 6 | $28,012 | Mar 25 | NuMetro Distribution | false |
| 36 | Getroud met Rugby: Die Onvertelde Storie | - | - | - | $6,808 | 41 | $208,531 | Mar 11 | Ster-Kinekor Pictures | false |
| 37 | How Do You Know | - | - | - | $4,134 | 44 | $546,914 | Feb 18 | Ster-Kinekor Pictures | false |
| 38 | Miral | - | - | - | $3,157 | 4 | $3,157 | Apr 15 | Ster-Kinekor Pictures | false |
| 39 | Of Gods and Men | - | - | - | $2,460 | 8 | $27,544 | Feb 25 | United International Pictures | false |
| 40 | Night Drive | - | - | - | $2,192 | 10 | $23,458 | Mar 4 | Indigenous Film Distribution | false |
| 41 | Morning Glory | - | - | - | $644 | 61 | $472,412 | Feb 11 | United International Pictures | false |
