| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Clash of the Titans | - | - | - | $3,958,626 | 103 | $4,736,074 | Apr 3 | Warner Bros. | false |
| 2 | Babe, I Love You | - | - | - | $1,859,642 | 70 | $2,168,605 | Apr 3 | Star Cinema | false |
| 3 | How to Train Your Dragon | - | - | - | $528,400 | 91 | $1,390,310 | Mar 19 | United International Pictures | false |
| 4 | Date Night | - | - | - | $363,180 | 50 | $483,275 | Apr 9 | 20th Century Fox International | false |
| 5 | Diary of a Wimpy Kid | - | - | - | $201,816 | 25 | $224,340 | Apr 3 | 20th Century Fox International | false |
| 6 | The Book of Eli | - | - | - | $157,587 | 30 | $528,495 | Mar 17 | Sony Pictures Releasing | false |
| 7 | The Back-up Plan | - | - | - | $155,142 | 40 | $276,714 | Apr 23 | Sony Pictures Releasing | false |
| 8 | Alice in Wonderland | - | - | - | $128,680 | 97 | $3,136,113 | Mar 4 | Walt Disney Pictures | false |
| 9 | Shutter Island | - | - | - | $119,768 | 14 | $256,820 | Apr 14 | United International Pictures | false |
| 10 | Possession | - | - | - | $78,149 | 20 | $78,149 | Apr 3 | Pioneer Films | false |
| 11 | Kick-Ass | - | - | - | $56,387 | 25 | $224,029 | Apr 16 | Viva International Pictures | false |
| 12 | Green Zone | - | - | - | $40,624 | 31 | $385,808 | Mar 12 | United International Pictures | false |
| 13 | I Love You Phillip Morris | - | - | - | $34,935 | 14 | $85,853 | Mar 24 | Pioneer Films | false |
| 14 | Hot Tub Time Machine | - | - | - | $33,009 | 16 | $33,009 | Apr 14 | Pioneer Films | false |
| 15 | Perkins' 14 | - | - | - | $32,013 | 14 | $103,054 | Mar 24 | Pioneer Films | false |
| 16 | Everybody's Fine | - | - | - | $15,676 | 1 | $15,676 | Apr 7 | Walt Disney Pictures | false |
| 17 | Miss You Like Crazy | - | - | - | $13,285 | 85 | $3,183,529 | Feb 24 | Star Cinema | false |
| 18 | When in Rome | - | - | - | $7,747 | 50 | $172,561 | Mar 17 | Walt Disney Pictures | false |
| 19 | Remember Me | - | - | - | $5,756 | 45 | $210,317 | Mar 12 | Pioneer Films | false |
| 20 | Invictus | - | - | - | $2,225 | 16 | $78,787 | Feb 17 | Warner Bros. | false |
| 21 | Cop Out | - | - | - | $1,823 | 50 | $258,672 | Mar 3 | Warner Bros. | false |
| 22 | Extraordinary Measures | - | - | - | $936 | 40 | $109,091 | Mar 10 | Sony Pictures Releasing | false |
| 23 | It's Complicated | - | - | - | $775 | 16 | $88,652 | Feb 24 | United International Pictures | false |
| 24 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $557 | 71 | $2,056,265 | Feb 12 | 20th Century Fox International | false |
| 25 | The Wolfman | - | - | - | $353 | 53 | $596,321 | Feb 12 | United International Pictures | false |
| 26 | Up in the Air | - | - | - | $287 | 12 | $81,875 | Mar 3 | United International Pictures | false |
| 27 | Valentine's Day | - | - | - | $262 | 50 | $752,679 | Feb 12 | Warner Bros. | false |
