| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Fast & Furious | - | - | - | $1,434,396 | 63 | $1,830,098 | Apr 9 | United International Pictures | false |
| 2 | Monsters vs. Aliens | - | - | - | $1,247,795 | 97 | $1,403,609 | Apr 3 | United International Pictures | false |
| 3 | Marley & Me | - | - | - | $847,942 | 65 | $1,440,176 | Mar 20 | NuMetro Distribution | false |
| 4 | 17 Again | - | - | - | $674,068 | 56 | $1,276,156 | Apr 17 | NuMetro Distribution | false |
| 5 | Slumdog Millionaire | - | - | - | $451,883 | 20 | $1,245,660 | Mar 6 | Ster-Kinekor Pictures | false |
| 6 | Race to Witch Mountain | - | - | - | $428,724 | 55 | $567,217 | Mar 27 | Ster-Kinekor Pictures | false |
| 7 | Confessions of a Shopaholic | - | - | - | $400,524 | 51 | $710,605 | Mar 13 | Ster-Kinekor Pictures | false |
| 8 | Dragonball Evolution | - | - | - | $272,607 | 35 | $293,010 | Apr 10 | 20th Century Fox International | false |
| 9 | Underworld: Rise of the Lycans | - | - | - | $207,679 | 35 | $262,809 | Mar 27 | Ster-Kinekor Pictures | false |
| 10 | Hotel for Dogs | - | - | - | $204,334 | 43 | $333,902 | Apr 17 | United International Pictures | false |
| 11 | Gran Torino | - | - | - | $203,839 | 40 | $295,574 | Mar 27 | NuMetro Distribution | false |
| 12 | He's Just Not That Into You | - | - | - | $196,948 | 51 | $931,784 | Feb 13 | NuMetro Distribution | false |
| 13 | The Curious Case of Benjamin Button | - | - | - | $195,475 | 55 | $685,513 | Feb 27 | NuMetro Distribution | false |
| 14 | The Reader | - | - | - | $193,983 | 10 | $339,802 | Mar 27 | Ster-Kinekor Pictures | false |
| 15 | 12 Rounds | - | - | - | $138,997 | 24 | $143,428 | Apr 3 | NuMetro Distribution | false |
| 16 | I Love You, Man | - | - | - | $135,574 | 50 | $293,781 | Apr 24 | United International Pictures | false |
| 17 | Watchmen | - | - | - | $118,663 | 62 | $460,229 | Mar 6 | Ster-Kinekor Pictures | false |
| 18 | The Pink Panther 2 | - | - | - | $118,583 | 75 | $632,208 | Feb 27 | Ster-Kinekor Pictures | false |
| 19 | Tornado 2009 Re-release | - | - | - | $110,152 | 42 | $110,152 | Apr 9 | Ster-Kinekor Pictures | false |
| 20 | The International | - | - | - | $93,181 | 19 | $225,447 | Apr 24 | Ster-Kinekor Pictures | false |
| 21 | Paul Blart: Mall Cop | - | - | - | $70,782 | 25 | $170,747 | Mar 13 | Ster-Kinekor Pictures | false |
| 22 | Finding Lenny | - | - | - | $55,662 | 43 | $55,662 | Apr 3 | NuMetro Distribution | false |
| 23 | Milk | - | - | - | $50,202 | 10 | $108,510 | Apr 24 | Ster-Kinekor Pictures | false |
| 24 | Defiance | - | - | - | $45,206 | 10 | $79,475 | Mar 20 | United International Pictures | false |
| 25 | Friday the 13th | - | - | - | $39,546 | 10 | $78,023 | Mar 13 | United International Pictures | false |
| 26 | Changeling | - | - | - | $26,945 | 29 | $210,663 | Feb 20 | United International Pictures | false |
| 27 | The Secret Life of Bees | - | - | - | $24,552 | 25 | $205,304 | Feb 6 | NuMetro Distribution | false |
| 28 | The Baader Meinhof Complex | - | - | - | $24,116 | 8 | $25,775 | Apr 3 | United International Pictures | false |
| 29 | Aa Dekhen Zara | - | - | - | $15,162 | 3 | $20,827 | Mar 27 | NuMetro Distribution | false |
| 30 | Revolutionary Road | - | - | - | $14,615 | 18 | $218,915 | Jan 23 | United International Pictures | false |
| 31 | 8 x 10 Tasveer | - | - | - | $11,443 | 4 | $14,890 | Apr 17 | NuMetro Distribution | false |
| 32 | Rachel Getting Married | - | - | - | $10,847 | 10 | $58,193 | Mar 13 | Ster-Kinekor Pictures | false |
| 33 | Seven Pounds | - | - | - | $8,514 | 50 | $309,025 | Feb 13 | Ster-Kinekor Pictures | false |
| 34 | Soul Men | - | - | - | $8,192 | 16 | $8,192 | Apr 3 | Ster-Kinekor Pictures | false |
| 35 | The Spirit | - | - | - | $6,914 | 10 | $6,914 | Apr 17 | Ster-Kinekor Pictures | false |
| 36 | Role Models | - | - | - | $1,139 | 44 | $214,599 | Feb 6 | United International Pictures | false |
| 37 | The Wrestler | - | - | - | $306 | 13 | $61,962 | Feb 20 | United International Pictures | false |
