| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | 21 | - | - | - | $5,005,521 | 255 | $6,840,432 | Apr 11 | Sony Pictures Releasing | false |
| 2 | Chef's Special | - | - | - | $4,632,474 | 232 | $7,819,057 | Apr 11 | Warner Bros. | false |
| 3 | Meet the Spartans | - | - | - | $3,484,020 | 316 | $6,542,138 | Mar 28 | 20th Century Fox International | false |
| 4 | The Game Plan | - | - | - | $3,468,047 | 250 | $6,016,924 | Mar 28 | Walt Disney Pictures | false |
| 5 | Shutter | - | - | - | $3,197,202 | 300 | $3,782,211 | Apr 11 | 20th Century Fox International | false |
| 6 | Death Defying Acts | - | - | - | $2,786,587 | 250 | $2,839,345 | Apr 4 | DeAPlaneta | false |
| 7 | We Own the Night | - | - | - | $2,205,167 | 224 | $3,742,720 | Mar 28 | Universal Pictures International (UPI) | false |
| 8 | Elegy | - | - | - | $2,068,646 | 128 | $3,914,620 | Apr 18 | On Pictures | false |
| 9 | Horton Hears a Who! | - | - | - | $1,951,746 | 476 | $11,301,036 | Mar 14 | 20th Century Fox International | false |
| 10 | Untraceable | - | - | - | $1,786,340 | 201 | $1,893,655 | Apr 4 | Universal Pictures International (UPI) | false |
| 11 | Street Kings | - | - | - | $1,658,454 | 302 | $4,185,842 | Apr 25 | 20th Century Fox International | false |
| 12 | Fool's Gold | - | - | - | $1,500,079 | 272 | $2,959,860 | Apr 25 | Warner Bros. | false |
| 13 | Never Back Down | - | - | - | $1,373,438 | 202 | $1,628,270 | Apr 18 | Aurum Films | false |
| 14 | The Contract | - | - | - | $1,259,849 | 121 | $1,885,696 | Apr 4 | Filmax | false |
| 15 | The Counterfeiters | - | - | - | $1,224,397 | 119 | $3,871,085 | Mar 14 | Wanda Visión S.A. | false |
| 16 | Rendition | - | - | - | $1,120,204 | 222 | $1,350,950 | Apr 18 | TriPictures | false |
| 17 | The Spiderwick Chronicles | - | - | - | $1,106,286 | 291 | $5,532,022 | Mar 14 | Universal Pictures International (UPI) | false |
| 18 | Todos estamos invitados | - | - | - | $1,059,556 | 111 | $1,251,557 | Apr 11 | Alta Films | false |
| 19 | 10,000 BC | - | - | - | $1,016,685 | 475 | $13,119,769 | Mar 7 | Warner Bros. | false |
| 20 | 8 Dates | - | - | - | $912,290 | 171 | $1,354,462 | Apr 18 | Alta Films | false |
| 21 | Awake | - | - | - | $896,665 | 206 | $1,513,431 | Mar 28 | Aurum Films | false |
| 22 | The Other Boleyn Girl | - | - | - | $739,455 | 217 | $5,865,854 | Feb 29 | Universal Pictures International (UPI) | false |
| 23 | The Savages | - | - | - | $708,978 | 48 | $989,819 | Apr 4 | 20th Century Fox International | false |
| 24 | The Ruins | - | - | - | $683,703 | 200 | $787,302 | Apr 18 | Universal Pictures International (UPI) | false |
| 25 | Cowards | - | - | - | $680,257 | 251 | $1,528,988 | Apr 25 | Filmax | false |
| 26 | Dan in Real Life | - | - | - | $649,513 | 191 | $2,706,563 | Mar 19 | Universal Pictures International (UPI) | false |
| 27 | Silk | - | - | - | $517,929 | 160 | $2,029,874 | Mar 19 | TriPictures | false |
| 28 | Juno | - | - | - | $484,106 | 200 | $8,237,494 | Feb 1 | 20th Century Fox International | false |
| 29 | A Thousand Years of Good Prayers | - | - | - | $479,547 | 337 | $1,163,809 | Apr 18 | Karma Films | false |
| 30 | No Country for Old Men | - | - | - | $477,937 | 308 | $10,785,397 | Feb 8 | Universal Pictures International (UPI) | false |
| 31 | The Edge of Heaven | - | - | - | $448,750 | 33 | $1,340,082 | Mar 14 | Golem Distribución | false |
| 32 | One Missed Call | - | - | - | $430,738 | 165 | $2,119,000 | Mar 19 | Warner Bros. | false |
| 33 | The Kite Runner | - | - | - | $407,464 | 135 | $1,870,588 | Mar 7 | Universal Pictures International (UPI) | false |
| 34 | The Water Horse | - | - | - | $403,862 | 205 | $3,438,882 | Mar 7 | Sony Pictures Releasing | false |
| 35 | American Gangster | - | - | - | $387,024 | 440 | $14,529,675 | Dec 28 | Universal Pictures International (UPI) | false |
| 36 | The Eye | - | - | - | $320,878 | 218 | $2,864,484 | Mar 14 | DeAPlaneta | false |
| 37 | 27 Dresses | - | - | - | $317,141 | 310 | $6,462,303 | Feb 29 | 20th Century Fox International | false |
| 38 | Jumper | - | - | - | $314,491 | 447 | $10,448,873 | Feb 15 | 20th Century Fox International | false |
| 39 | Mortadelo and Filemon: Mission - Save the Planet | - | - | - | $313,744 | 492 | $11,945,068 | Jan 25 | On Pictures | false |
| 40 | Be Kind Rewind | - | - | - | $304,562 | 32 | $561,516 | Apr 11 | Universal Pictures International (UPI) | false |
| 41 | Rogue | - | - | - | $287,476 | 122 | $291,329 | Apr 4 | Notro Films | false |
| 42 | The Band's Visit | - | - | - | $273,273 | 27 | $462,560 | Apr 11 | Manga Entertainment | false |
| 43 | Charlie Wilson's War | - | - | - | $265,509 | 256 | $4,433,377 | Feb 22 | Universal Pictures International (UPI) | false |
| 44 | Shine a Light | - | - | - | $259,206 | 67 | $277,526 | Apr 4 | Vértigo Films | false |
| 45 | The Oxford Murders | - | - | - | $234,119 | 271 | $12,525,441 | Jan 18 | Warner Bros. | false |
| 46 | Vantage Point | - | - | - | $226,275 | 373 | $6,721,872 | Feb 28 | Sony Pictures Releasing | false |
| 47 | Days of Darkness | - | - | - | $222,313 | 26 | $380,203 | Apr 11 | Golem Distribución | false |
| 48 | Asterix at the Olympic Games | - | - | - | $219,948 | 385 | $9,181,000 | Feb 8 | TriPictures | false |
| 49 | Before the Fall | - | - | - | $211,008 | 128 | $328,946 | Apr 25 | Universal Pictures International (UPI) | false |
| 50 | The Bucket List | - | - | - | $195,420 | 270 | $5,682,938 | Feb 1 | Warner Bros. | false |
| 51 | Sweeney Todd: The Demon Barber of Fleet Street | - | - | - | $188,148 | 274 | $5,144,278 | Feb 15 | Warner Bros. | false |
| 52 | Things We Lost in the Fire | - | - | - | $151,768 | 68 | $322,292 | Apr 25 | Universal Pictures International (UPI) | false |
| 53 | There Will Be Blood | - | - | - | $148,704 | 104 | $2,415,805 | Feb 15 | Walt Disney Pictures | false |
| 54 | Rambo | - | - | - | $139,765 | 348 | $5,323,543 | Feb 1 | Manga Entertainment | false |
| 55 | Cashback | - | - | - | $131,835 | 26 | $206,570 | Apr 11 | Laurenfilm | false |
| 56 | Enloquecidas | - | - | - | $111,993 | 10 | $200,134 | Apr 11 | Premium Film | false |
| 57 | Lo mejor de mà | - | - | - | $92,009 | 30 | $401,227 | Mar 7 | Alta Films | false |
| 58 | Buddha Collapsed Out of Shame | - | - | - | $88,028 | 19 | $489,438 | Feb 29 | Wanda Visión S.A. | false |
| 59 | Caramel | - | - | - | $87,402 | 60 | $1,848,875 | Jan 18 | Alta Films | false |
| 60 | 4 Months, 3 Weeks and 2 Days | - | - | - | $82,626 | 36 | $1,063,172 | Jan 25 | Golem Distribución | false |
| 61 | Rudy: The Return of the Racing Pig | - | - | - | $76,012 | 64 | $407,216 | Apr 25 | Flins & Piniculas | false |
| 62 | Bab'Aziz: The Prince That Contemplated His Soul | - | - | - | $73,996 | 6 | $257,291 | Mar 7 | Karma Films | false |
| 63 | Lars and the Real Girl | - | - | - | $71,965 | 21 | $287,503 | Apr 25 | Versus Entertainment | false |
| 64 | Mirror Maze | - | - | - | $69,371 | 124 | $119,572 | Apr 25 | Walt Disney Pictures | false |
| 65 | Sleeping Dogs Lie | - | - | - | $67,084 | 23 | $342,196 | Mar 7 | Laurenfilm | false |
| 66 | Lust, Caution | - | - | - | $60,977 | 126 | $2,247,011 | Dec 14 | Universal Pictures International (UPI) | false |
| 67 | Franklin and the Turtle Lake Treasure | - | - | - | $52,884 | 106 | $766,086 | Feb 22 | Wanda Visión S.A. | false |
| 68 | La soledad | - | - | - | $46,475 | 40 | $1,020,921 | Jun 1 | Wanda Visión S.A. | false |
| 69 | Joe Strummer: The Future Is Unwritten | - | - | - | $45,962 | 4 | $46,332 | Apr 4 | Avalon | false |
| 70 | It's a Free World... | - | - | - | $41,548 | 85 | $565,458 | Feb 22 | Alta Films | false |
| 71 | Irina Palm | - | - | - | $41,447 | 32 | $807,806 | Dec 14 | Golem Distribución | false |
| 72 | Closing the Ring | - | - | - | $38,511 | 24 | $269,893 | Mar 14 | Manga Entertainment | false |
| 73 | The Pope's Toilet | - | - | - | $33,318 | 15 | $94,542 | Apr 25 | Golem Distribución | false |
| 74 | Rise: Blood Hunter | - | - | - | $31,913 | 150 | $823,623 | Feb 29 | Aurum Films | false |
| 75 | Into the Wild | - | - | - | $31,805 | 81 | $780,998 | Jan 25 | Universal Pictures International (UPI) | false |
| 76 | Once | - | - | - | $29,183 | 27 | $879,999 | Oct 31 | Avalon | false |
| 77 | This Is England | - | - | - | $26,459 | 40 | $739,369 | Jan 4 | Festival Films S.L. | false |
| 78 | The Last Mimzy | - | - | - | $26,259 | 156 | $985,263 | Jan 4 | TriPictures | false |
| 79 | Private Fears in Public Places | - | - | - | $26,188 | 18 | $288,742 | Feb 15 | Baditri | false |
| 80 | Love and Honor | - | - | - | $25,609 | 4 | $37,174 | Mar 28 | Notro Films | false |
| 81 | The Silence Before Bach | - | - | - | $23,618 | 5 | $322,116 | Dec 21 | Sherlock Films | false |
| 82 | Love Sick 2008 Re-release | - | - | - | $19,993 | 11 | $36,446 | Mar 28 | Baditri | false |
| 83 | KM 31: Kilometre 31 | - | - | - | $19,521 | 96 | $597,338 | Feb 15 | Filmax | false |
| 84 | El último justo | - | - | - | $17,547 | 126 | $368,925 | Feb 29 | Filmax | false |
| 85 | Across the Universe | - | - | - | $15,814 | 30 | $135,227 | Jan 4 | Sony Pictures Releasing | false |
| 86 | Black Gold | - | - | - | $15,389 | 11 | $25,561 | Mar 28 | Karma Films | false |
| 87 | Pingpong | - | - | - | $13,248 | 3 | $22,407 | Mar 28 | Sherlock Films | false |
| 88 | I Want Candy | - | - | - | $12,781 | 56 | $226,842 | Mar 14 | Flins & Piniculas | false |
| 89 | El menor de los males | - | - | - | $12,038 | 56 | $173,694 | Mar 14 | Filmax | false |
| 90 | Women on the Verge of a Nervous Breakdown 2008 Re-release | - | - | - | $10,809 | 5 | $10,840 | Apr 11 | Warner Bros. | false |
| 91 | The Diving Bell and the Butterfly | - | - | - | $9,954 | 57 | $356,647 | Feb 1 | Vértigo Films | false |
| 92 | LT22 Radio La Colifata | - | - | - | $9,488 | 4 | $9,488 | Apr 4 | Sagrera TV | false |
| 93 | Myway | - | - | - | $6,734 | 46 | $156,591 | Feb 1 | Baditri | false |
| 94 | Back to Normandy | - | - | - | $6,238 | 8 | $14,138 | Mar 28 | Karma Films | false |
| 95 | 30 Days of Night | - | - | - | $6,132 | 300 | $4,113,870 | Feb 8 | Sony Pictures Releasing | false |
| 96 | Dreams | - | - | - | $5,942 | 2 | $24,972 | Mar 19 | Sagrera TV | false |
| 97 | The Call of Wild | - | - | - | $5,557 | 52 | $96,220 | Mar 7 | Notro Films | false |
| 98 | Seraphim Falls | - | - | - | $4,570 | 52 | $100,168 | Mar 7 | Aurum Films | false |
| 99 | Silent Light | - | - | - | $4,151 | 6 | $49,389 | Feb 22 | Golem Distribución | false |
| 100 | Fantasia 2000 | - | - | - | $3,316 | 1 | $392,458 | Jul 14 | Walt Disney Pictures | false |
| 101 | The Missing Star | - | - | - | $2,393 | 5 | $67,299 | Jan 11 | Filmax | false |
| 102 | Japón 2008 Re-release | - | - | - | $1,122 | 4 | $10,082 | Mar 7 | Golem Distribución | false |
