| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Spiderwick Chronicles | - | - | - | $6,511,318 | 269 | $7,350,921 | Apr 3 | Paramount Pictures International | false |
| 2 | Horton Hears a Who! | - | - | - | $5,080,624 | 363 | $11,262,758 | Mar 20 | 20th Century Fox International | false |
| 3 | Nim's Island | - | - | - | $5,063,664 | 196 | $5,819,517 | Apr 3 | Universal Pictures International (UPI) | false |
| 4 | Forgetting Sarah Marshall | - | - | - | $4,350,767 | 255 | $6,456,024 | Apr 17 | Universal Pictures International (UPI) | false |
| 5 | Semi-Pro | - | - | - | $3,683,341 | 202 | $3,890,603 | Apr 3 | Roadshow Films | false |
| 6 | Step Up 2: The Streets | - | - | - | $3,249,566 | 188 | $8,657,437 | Mar 20 | Universal Pictures International (UPI) | false |
| 7 | Street Kings | - | - | - | $3,078,164 | 222 | $3,878,910 | Apr 17 | 20th Century Fox International | false |
| 8 | Superhero Movie | - | - | - | $3,046,748 | 188 | $3,220,326 | Apr 10 | Roadshow Films | false |
| 9 | Prom Night | - | - | - | $2,378,182 | 124 | $2,566,794 | Apr 10 | Sony Pictures Releasing | false |
| 10 | Never Back Down | - | - | - | $2,044,842 | 151 | $3,055,171 | Mar 27 | Roadshow Films | false |
| 11 | St. Trinian's | - | - | - | $1,803,236 | 209 | $2,508,880 | Mar 27 | Sony Pictures Releasing | false |
| 12 | The Other Boleyn Girl | - | - | - | $1,201,595 | 132 | $3,792,878 | Mar 13 | Universal Pictures International (UPI) | false |
| 13 | Vantage Point | - | - | - | $1,022,685 | 196 | $4,281,938 | Mar 13 | Sony Pictures Releasing | false |
| 14 | U2 3D | - | - | - | $917,813 | 23 | $990,192 | Apr 10 | Roadshow Films | false |
| 15 | The Painted Veil | - | - | - | $798,068 | 63 | $3,453,372 | Apr 24 | Paramount Pictures International | false |
| 16 | Before the Devil Knows You're Dead | - | - | - | $795,206 | 46 | $1,539,246 | Mar 20 | Hopscotch Films | false |
| 17 | The Black Balloon | - | - | - | $774,956 | 76 | $2,105,473 | Mar 6 | Icon Film Distribution Australia | false |
| 18 | Lars and the Real Girl | - | - | - | $773,113 | 39 | $1,398,865 | Apr 3 | Rialto Distribution | false |
| 19 | Deception | - | - | - | $761,572 | 112 | $1,447,588 | Apr 24 | 20th Century Fox International | false |
| 20 | The Bucket List | - | - | - | $692,427 | 256 | $7,385,515 | Feb 21 | Warner Bros. | false |
| 21 | Gone Baby Gone | - | - | - | $691,306 | 40 | $1,310,611 | Apr 17 | Walt Disney Pictures | false |
| 22 | Untraceable | - | - | - | $623,709 | 122 | $1,020,322 | Apr 24 | Universal Pictures International (UPI) | false |
| 23 | Paris | - | - | - | $538,120 | 30 | $694,134 | Apr 10 | Icon Film Distribution Australia | false |
| 24 | 10,000 BC | - | - | - | $497,686 | 221 | $6,276,216 | Mar 6 | Warner Bros. | false |
| 25 | Smart People | - | - | - | $465,605 | 132 | $669,238 | Apr 24 | Icon Film Distribution Australia | false |
| 26 | Be Kind Rewind | - | - | - | $386,946 | 42 | $920,837 | Mar 20 | Roadshow Films | false |
| 27 | How She Move | - | - | - | $379,863 | 100 | $379,863 | Apr 10 | Paramount Pictures International | false |
| 28 | Brick Lane | - | - | - | $320,722 | 25 | $629,347 | Mar 20 | Madman Entertainment | false |
| 29 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | - | - | - | $293,738 | 20 | $1,204,893 | Mar 20 | Walt Disney Pictures | false |
| 30 | The Kite Runner | - | - | - | $261,709 | 54 | $2,733,844 | Jan 17 | Paramount Pictures International | false |
| 31 | Dolphins and Whales 3D: Tribes of the Ocean | - | - | - | $216,528 | 1 | $589,427 | Mar 13 | IMAX | false |
| 32 | The Eye | - | - | - | $212,473 | 125 | $1,412,165 | Mar 13 | Paramount Pictures International | false |
| 33 | Hey Hey It's Esther Blueburger | - | - | - | $187,208 | 134 | $780,730 | Mar 20 | Walt Disney Pictures | false |
| 34 | African Adventure: Safari in the Okavango | - | - | - | $177,856 | 2 | $811,654 | Mar 20 | IMAX | false |
| 35 | L'invité | - | - | - | $170,981 | 15 | $266,173 | Mar 20 | Dendy Films | false |
| 36 | The Edge of Heaven | - | - | - | $168,294 | 17 | $684,381 | Apr 24 | Sharmill Films | false |
| 37 | There Will Be Blood | - | - | - | $166,855 | 68 | $7,843 | - | Walt Disney Pictures | false |
| 38 | No Country for Old Men | - | - | - | $165,963 | 85 | $5,625,870 | - | Paramount Pictures International | false |
| 39 | Tashan | - | - | - | $148,087 | 13 | $222,019 | Apr 24 | MG Distribution | false |
| 40 | Run Fatboy Run | - | - | - | $146,048 | 238 | $3,196,789 | Mar 6 | Roadshow Films | false |
| 41 | Jumper | - | - | - | $139,411 | 273 | $8,301,391 | Feb 14 | 20th Century Fox International | false |
| 42 | Sweeney Todd: The Demon Barber of Fleet Street | - | - | - | $132,897 | 127 | $5,132,480 | Jan 24 | Warner Bros. | false |
| 43 | U Me Aur Hum | - | - | - | $126,269 | 8 | $135,607 | Apr 10 | Eros Worldwide | false |
| 44 | The Diving Bell and the Butterfly | - | - | - | $125,142 | 37 | $994,798 | Feb 14 | Icon Film Distribution Australia | false |
| 45 | In the Valley of Elah | - | - | - | $99,385 | 44 | $572,768 | Feb 28 | Hoyts Distribution | false |
| 46 | In the Shadow of the Moon | - | - | - | $90,466 | 19 | $376,147 | Mar 6 | Madman Entertainment | false |
| 47 | 27 Dresses | - | - | - | $88,895 | 249 | $14,325,769 | Jan 10 | 20th Century Fox International | false |
| 48 | The Secret of the Grain | - | - | - | $88,386 | 14 | $360,950 | Mar 20 | Palace Films | false |
| 49 | Deep Sea | - | - | - | $80,814 | 2 | $3,696,215 | Mar 3 | IMAX | false |
| 50 | Closing the Ring | - | - | - | $78,293 | 54 | $385,671 | Mar 6 | Hopscotch Films | false |
| 51 | Juno | - | - | - | $78,149 | 197 | $10,951,850 | Jan 17 | Walt Disney Studios Motion Pictures | false |
| 52 | Fool's Gold | - | - | - | $73,722 | 192 | $4,945,729 | Feb 7 | Warner Bros. | false |
| 53 | Haunted Castle | - | - | - | $62,045 | 4 | $3,786,220 | Sep 20 | IMAX | false |
| 54 | Dinosaurs: Giants of Patagonia | - | - | - | $57,573 | 2 | $2,085,442 | Jun 7 | IMAX | false |
| 55 | Definitely, Maybe | - | - | - | $57,364 | 199 | $4,168,132 | Feb 14 | Universal Pictures International (UPI) | false |
| 56 | Sea Monsters: A Prehistoric Adventure | - | - | - | $56,830 | 2 | $1,266,745 | Sep 20 | IMAX | false |
| 57 | Meet the Spartans | - | - | - | $56,546 | 211 | $2,771,188 | Feb 28 | 20th Century Fox International | false |
| 58 | Race | - | - | - | $47,878 | 14 | $330,599 | Mar 20 | MG Distribution | false |
| 59 | Two Days in Paris | - | - | - | $43,694 | 37 | $1,724,376 | Dec 26 | Hopscotch Films | false |
| 60 | Lust, Caution | - | - | - | $42,312 | 12 | $800,994 | Jan 17 | Park Circus | false |
| 61 | Krazzy 4 | - | - | - | $39,303 | 5 | $39,303 | Apr 10 | Eros Worldwide | false |
| 62 | Bella | - | - | - | $31,701 | 21 | $199,690 | Feb 21 | Hopscotch Films | false |
| 63 | 3:10 to Yuma | - | - | - | $30,822 | 207 | $2,371,873 | Jan 31 | Hoyts Distribution | false |
| 64 | The Ten Commandments | - | - | - | $26,571 | 31 | $56,355 | Apr 24 | IDT Home Entertainment | false |
| 65 | Grindhouse | - | - | - | $19,796 | 2 | $109,275 | Dec 13 | Roadshow Films | false |
| 66 | Global Haywire | - | - | - | $17,247 | 4 | $19,554 | Apr 10 | Hopscotch Films | false |
| 67 | One Two Three | - | - | - | $16,789 | 7 | $38,339 | Mar 27 | Eros Worldwide | false |
| 68 | Black Water | - | - | - | $15,606 | 12 | $98,901 | Apr 24 | All Interactive Distribution | false |
| 69 | Paranoid Park | - | - | - | $13,456 | 5 | $71,749 | Mar 6 | Madman Entertainment | false |
| 70 | Deep Water | - | - | - | $13,343 | 6 | $229,740 | Oct 11 | Hopscotch Films | false |
| 71 | Death Defying Acts | - | - | - | $11,139 | 125 | $655,731 | Mar 13 | Dendy Films | false |
| 72 | Rendition | - | - | - | $9,159 | 48 | $436,182 | Feb 14 | Roadshow Films | false |
| 73 | August Rush | - | - | - | $7,589 | 109 | $654,865 | Feb 21 | Magna Pacific | false |
| 74 | Shackleton's Antarctic Adventure | - | - | - | $2,792 | 3 | $4,030,122 | Nov 1 | - | false |
| 75 | Antarctica | - | - | - | $2,115 | 2 | $4,075,362 | Dec 1 | IMAX | false |
| 76 | Transylvania | - | - | - | $1,947 | 1 | $11,405 | Jan 17 | Potential Films | false |
| 77 | Broken Sun | - | - | - | $1,622 | 2 | $4,799 | Apr 24 | JackaFilms | false |
| 78 | Mysteries of Egypt | - | - | - | $1,016 | 2 | $4,110,245 | Jan 28 | IMAX | false |
| 79 | Space Station 3D | - | - | - | $729 | 2 | $3,436,855 | - | IMAX | false |
| 80 | After Him | - | - | - | $682 | 5 | $60,443 | Mar 27 | Palace Films | false |
| 81 | The King of Kong: A Fistful of Quarters | - | - | - | $353 | 8 | $96,628 | Feb 28 | Dendy Films | false |
