| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Ring Two | - | - | - | $6,576,422 | 381 | $7,199,962 | Apr 8 | United International Pictures | false |
| 2 | Manual of Love | - | - | - | $6,114,355 | 484 | $19,605,249 | Mar 18 | Filmauro | false |
| 3 | La febbre | - | - | - | $3,720,615 | 249 | $3,813,551 | Apr 1 | 01 Distribution | false |
| 4 | Hitch | - | - | - | $3,485,943 | 296 | $10,698,009 | Mar 11 | Sony Pictures Releasing | false |
| 5 | Il ritorno del Monnezza | - | - | - | $3,171,183 | 271 | $3,273,446 | Apr 15 | Medusa Distribuzione | false |
| 6 | Be Cool | - | - | - | $2,926,761 | 271 | $3,169,572 | Apr 15 | 20th Century Fox International | false |
| 7 | Sahara | - | - | - | $2,377,616 | 200 | $3,325,503 | Apr 22 | United International Pictures | false |
| 8 | The Pacifier | - | - | - | $2,257,967 | 200 | $3,072,938 | Apr 22 | Buena Vista International | false |
| 9 | Robots | - | - | - | $1,616,316 | 406 | $3,495,457 | Mar 24 | 20th Century Fox International | false |
| 10 | After the Sunset | - | - | - | $1,538,041 | 168 | $1,538,041 | Apr 8 | 01 Distribution | false |
| 11 | The Upside of Anger | - | - | - | $1,492,414 | 232 | $1,492,414 | Apr 15 | Eagle Pictures | false |
| 12 | Ferpect Crime | - | - | - | $1,486,475 | 159 | $1,486,475 | Apr 8 | Nexo | false |
| 13 | The Jacket | - | - | - | $1,165,565 | 144 | $1,165,565 | Apr 1 | Italian International Film | false |
| 14 | Million Dollar Baby | - | - | - | $964,078 | 270 | $9,843,810 | Feb 18 | 01 Distribution | false |
| 15 | Cose da pazzi | - | - | - | $920,861 | 153 | $2,384,156 | Mar 25 | Medusa Distribuzione | false |
| 16 | Too Beautiful | - | - | - | $899,756 | 309 | $903,391 | Apr 22 | Medusa Distribuzione | false |
| 17 | A Series of Unfortunate Events | - | - | - | $823,053 | 214 | $2,863,638 | Mar 18 | United International Pictures | false |
| 18 | The Eye 2 | - | - | - | $808,724 | 233 | $808,724 | Apr 1 | Eagle Pictures | false |
| 19 | Son of the Mask | - | - | - | $780,571 | 204 | $826,173 | Apr 1 | Medusa Distribuzione | false |
| 20 | Head in the Clouds | - | - | - | $488,216 | 242 | $1,972,835 | Apr 29 | Moviemax | false |
| 21 | xXx: State of the Union | - | - | - | $447,204 | 244 | $1,029,910 | Apr 29 | Sony Pictures Releasing | false |
| 22 | Deep Blue | - | - | - | $434,323 | 79 | $434,366 | Apr 8 | Lucky Red | false |
| 23 | Tutti all'attacco | - | - | - | $380,841 | 162 | $380,841 | Apr 22 | Warner Bros. | false |
| 24 | Racing Stripes | - | - | - | $334,648 | 186 | $969,450 | Mar 25 | Eagle Pictures | false |
| 25 | Spanglish | - | - | - | $330,202 | 62 | $330,202 | Apr 15 | Sony Pictures Releasing | false |
| 26 | L'uomo perfetto | - | - | - | $328,137 | 142 | $1,881,273 | Apr 29 | Warner Bros. | false |
| 27 | Cellular | - | - | - | $316,358 | 226 | $697,707 | Apr 29 | Eagle Pictures | false |
| 28 | Downfall | - | - | - | $303,554 | 122 | $1,719,541 | Apr 29 | 01 Distribution | false |
| 29 | In Good Company | - | - | - | $292,349 | 145 | $811,897 | Mar 25 | BIM Distribuzione | false |
| 30 | Harold & Kumar Go to White Castle | - | - | - | $289,958 | 68 | $380,841 | Apr 22 | CDI Films | false |
| 31 | Hostage | - | - | - | $274,501 | 201 | $1,587,979 | Mar 18 | Medusa Distribuzione | false |
| 32 | Pooh's Heffalump Movie | - | - | - | $266,078 | 167 | $1,183,573 | Mar 18 | Buena Vista International | false |
| 33 | We Don't Live Here Anymore | - | - | - | $257,379 | 60 | $257,379 | Apr 22 | BIM Distribuzione | false |
| 34 | Sword in the Moon | - | - | - | $189,634 | 133 | $189,634 | Apr 8 | Moviemax | false |
| 35 | The Wedding Date | - | - | - | $136,353 | 114 | $326,697 | Apr 29 | Medusa Distribuzione | false |
| 36 | Super Size Me | - | - | - | $98,815 | 60 | $98,831 | Apr 8 | Fandango | false |
| 37 | La terza stella | - | - | - | $96,840 | 216 | $2,146,864 | Mar 11 | Medusa Distribuzione | false |
| 38 | Laura's Star | - | - | - | $95,015 | 119 | $95,015 | Apr 22 | Warner Bros. | false |
| 39 | Cursed | - | - | - | $81,598 | 79 | $463,791 | Mar 25 | Buena Vista International | false |
| 40 | Enduring Love | - | - | - | $73,643 | 33 | $170,462 | Apr 8 | Mikado Film | false |
| 41 | Suspect Zero | - | - | - | $73,631 | 57 | $376,256 | Mar 25 | Sony Pictures Releasing | false |
| 42 | Tickets | - | - | - | $71,393 | 68 | $299,566 | Mar 25 | Medusa Distribuzione | false |
| 43 | Flight of the Phoenix | - | - | - | $68,439 | 79 | $119,418 | Apr 29 | 20th Century Fox International | false |
| 44 | Sacred Heart | - | - | - | $52,772 | 319 | $3,804,570 | Feb 25 | Medusa Distribuzione | false |
| 45 | Il resto di niente | - | - | - | $52,217 | 19 | $156,252 | Mar 25 | Istituto Luce | false |
