| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Happy Feet | - | - | - | $43,183,255 | 3,804 | $198,000,317 | Nov 17 | Warner Bros. | false |
| 2 | Casino Royale | - | - | - | $38,324,799 | 3,443 | $167,445,960 | Nov 17 | Sony Pictures Releasing | false |
| 3 | Deja Vu | - | - | - | $25,110,863 | 3,108 | $64,038,616 | Nov 22 | Walt Disney Studios Motion Pictures | false |
| 4 | Deck the Halls | - | - | - | $14,893,450 | 3,205 | $35,093,569 | Nov 22 | Twentieth Century Fox | false |
| 5 | Borat | - | - | - | $12,854,561 | 2,611 | $128,505,958 | Nov 3 | Twentieth Century Fox | false |
| 6 | The Santa Clause 3: The Escape Clause | - | - | - | $12,008,435 | 3,458 | $84,500,122 | Nov 3 | Walt Disney Studios Motion Pictures | false |
| 7 | Stranger Than Fiction | - | - | - | $7,033,423 | 2,270 | $40,660,952 | Nov 10 | Sony Pictures Releasing | false |
| 8 | Flushed Away | - | - | - | $6,550,149 | 3,707 | $64,665,672 | Nov 3 | DreamWorks | false |
| 9 | Bobby | - | - | - | $6,012,101 | 1,670 | $11,242,801 | Nov 17 | Metro-Goldwyn-Mayer (MGM) | false |
| 10 | The Fountain | - | - | - | $4,630,809 | 1,472 | $10,144,010 | Nov 22 | Warner Bros. | false |
| 11 | Tenacious D in the Pick of Destiny | - | - | - | $4,030,879 | 1,919 | $8,334,575 | Nov 22 | New Line Cinema | true |
| 12 | The Queen | - | - | - | $2,949,471 | 1,850 | $56,441,711 | Sep 30 | Miramax | true |
| 13 | Babel | - | - | - | $2,293,808 | 1,251 | $34,302,837 | Oct 27 | Paramount Vantage | false |
| 14 | For Your Consideration | - | - | - | $2,281,499 | 625 | $5,549,923 | Nov 17 | Warner Independent Pictures (WIP) | false |
| 15 | The Departed | - | - | - | $2,043,540 | 3,017 | $132,384,315 | Oct 6 | Warner Bros. | false |
| 16 | Saw III | - | - | - | $1,981,868 | 3,167 | $80,238,724 | Oct 27 | Lionsgate | false |
| 17 | Dhoom 2 | - | - | - | $1,298,477 | 63 | $2,643,586 | Nov 23 | Yash Raj Films | false |
| 18 | Let's Go to Prison | - | - | - | $1,226,560 | 1,495 | $4,630,045 | Nov 17 | Universal Pictures | false |
| 19 | The Prestige | - | - | - | $1,072,195 | 2,305 | $53,089,891 | Oct 20 | Walt Disney Studios Motion Pictures | false |
| 20 | Flags of Our Fathers | - | - | - | $362,153 | 2,375 | $33,602,376 | Oct 20 | DreamWorks | false |
| 21 | A Good Year | - | - | - | $350,801 | 2,067 | $7,459,300 | Nov 10 | Twentieth Century Fox | false |
| 22 | The Polar Express 2006 IMAX Release | - | - | - | $255,690 | 37 | $2,940,722 | Nov 17 | Warner Bros. | false |
| 23 | Fast Food Nation | - | - | - | $237,009 | 321 | $1,005,539 | Nov 17 | Fox Searchlight Pictures | false |
| 24 | Flicka | - | - | - | $186,351 | 2,877 | $21,000,147 | Oct 20 | Twentieth Century Fox | false |
| 25 | Marie Antoinette | - | - | - | $177,759 | 870 | $15,962,471 | Oct 20 | Sony Pictures Releasing | false |
| 26 | Open Season | - | - | - | $169,254 | 3,833 | $85,105,259 | Sep 29 | Sony Pictures Releasing | false |
| 27 | The Illusionist | - | - | - | $159,344 | 1,438 | $39,868,642 | Aug 18 | Yari Film Group Releasing | false |
| 28 | The Wedding Weekend | - | - | - | $146,289 | 84 | $1,232,961 | Oct 27 | The Weinstein Company | false |
| 29 | Deep Sea | - | - | - | $144,059 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 30 | Little Miss Sunshine | - | - | - | $138,694 | 1,602 | $59,891,098 | Jul 26 | Fox Searchlight Pictures | false |
| 31 | Man of the Year | - | - | - | $122,320 | 2,626 | $37,327,390 | Oct 13 | Universal Pictures | false |
| 32 | The Marine | - | - | - | $120,667 | 2,545 | $18,844,784 | Oct 13 | Twentieth Century Fox | false |
| 33 | The History Boys | - | - | - | $118,305 | 165 | $2,706,659 | Nov 21 | Fox Searchlight Pictures | false |
| 34 | Jackass Number Two | - | - | - | $82,157 | 3,063 | $72,778,712 | Sep 22 | Paramount Pictures | false |
| 35 | School for Scoundrels | - | - | - | $81,509 | 3,007 | $17,807,569 | Sep 29 | Metro-Goldwyn-Mayer (MGM) | false |
| 36 | The Last King of Scotland | - | - | - | $77,916 | 540 | $17,606,684 | Sep 27 | Fox Searchlight Pictures | false |
| 37 | The Return | - | - | - | $57,268 | 1,986 | $7,749,851 | Nov 10 | Rogue Pictures | false |
| 38 | Harsh Times | - | - | - | $54,155 | 956 | $3,337,931 | Nov 10 | Metro-Goldwyn-Mayer (MGM) | false |
| 39 | Fur: An Imaginary Portrait of Diane Arbus | - | - | - | $39,212 | 39 | $223,202 | Nov 10 | Picturehouse | false |
| 40 | Employee of the Month | - | - | - | $38,788 | 2,579 | $28,444,855 | Oct 6 | Lionsgate | false |
| 41 | Copying Beethoven | - | - | - | $37,946 | 29 | $384,029 | Nov 10 | Metro-Goldwyn-Mayer (MGM) | false |
| 42 | The Science of Sleep | - | - | - | $20,107 | 243 | $4,670,644 | Sep 22 | Warner Independent Pictures (WIP) | false |
| 43 | Everyone's Hero | - | - | - | $11,440 | 2,898 | $14,523,101 | Sep 15 | Twentieth Century Fox | false |
| 44 | The Devil Wears Prada | - | - | - | $11,230 | 2,882 | $124,740,460 | Jun 30 | Twentieth Century Fox | false |
| 45 | The U.S. vs. John Lennon | - | - | - | $9,828 | 65 | $1,109,146 | Sep 15 | Lionsgate | false |
| 46 | Deliver Us from Evil | - | - | - | $8,685 | 24 | $201,275 | Oct 13 | Lionsgate | false |
| 47 | Infamous | - | - | - | $2,688 | 179 | $1,151,330 | Oct 13 | Warner Independent Pictures (WIP) | false |
| 48 | Who the #$&% Is Jackson Pollock? | - | - | - | $2,537 | 2 | $13,710 | Nov 15 | Picturehouse | false |
| 49 | Hannari: Geisha Modern | - | - | - | $1,907 | 1 | $14,974 | Nov 17 | Sakura Productions USA | false |
| 50 | Flyboys | - | - | - | $985 | 2,033 | $13,090,630 | Sep 22 | Metro-Goldwyn-Mayer (MGM) | false |
