| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Spiderwick Chronicles | - | - | - | $5,736,479 | 3,847 | $71,195,053 | Feb 14 | Paramount Pictures | false |
| 2 | Jumper | - | - | - | $4,738,183 | 3,430 | $80,172,128 | Feb 14 | Twentieth Century Fox | false |
| 3 | Step Up 2: The Streets | - | - | - | $3,216,603 | 2,528 | $58,017,783 | Feb 14 | Walt Disney Studios Motion Pictures | false |
| 4 | Fool's Gold | - | - | - | $1,946,347 | 3,125 | $70,231,041 | Feb 8 | Warner Bros. | false |
| 5 | Definitely, Maybe | - | - | - | $1,707,985 | 2,220 | $32,241,649 | Feb 14 | Universal Pictures | false |
| 6 | Welcome Home, Roscoe Jenkins | - | - | - | $1,445,025 | 2,387 | $42,436,517 | Feb 8 | Universal Pictures | false |
| 7 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | - | - | - | $1,123,660 | 687 | $65,281,781 | Feb 1 | Walt Disney Studios Motion Pictures | false |
| 8 | Juno | - | - | - | $970,124 | 2,534 | $143,495,265 | Dec 5 | - | false |
| 9 | 27 Dresses | - | - | - | $687,890 | 3,074 | $76,808,654 | Jan 18 | Twentieth Century Fox | false |
| 10 | The Bucket List | - | - | - | $683,250 | 2,915 | $93,466,502 | Dec 25 | Warner Bros. | false |
| 11 | There Will Be Blood | - | - | - | $643,254 | 1,620 | $40,222,514 | Dec 26 | Paramount Vantage | false |
| 12 | The Eye | - | - | - | $536,493 | 2,470 | $31,418,697 | Feb 1 | Lionsgate Films | false |
| 13 | Alvin and the Chipmunks | - | - | - | $469,768 | 3,499 | $217,326,974 | Dec 14 | Twentieth Century Fox | false |
| 14 | No Country for Old Men | - | - | - | $411,187 | 2,037 | $74,283,625 | Nov 9 | Miramax | false |
| 15 | Rambo | - | - | - | $398,848 | 2,764 | $42,754,105 | Jan 25 | Lionsgate Films | false |
| 16 | National Treasure: Book of Secrets | - | - | - | $339,607 | 3,832 | $219,964,115 | Dec 21 | Walt Disney Studios Motion Pictures | false |
| 17 | Meet the Spartans | - | - | - | $324,780 | 2,643 | $38,233,676 | Jan 25 | Twentieth Century Fox | false |
| 18 | Untraceable | - | - | - | $309,308 | 2,368 | $28,687,835 | Jan 25 | Screen Gems | false |
| 19 | Atonement | - | - | - | $304,141 | 1,400 | $50,927,067 | Dec 7 | Focus Features | false |
| 20 | Cloverfield | - | - | - | $228,054 | 3,411 | $80,048,433 | Jan 18 | Paramount Pictures | false |
| 21 | Michael Clayton | - | - | - | $200,888 | 2,585 | $49,033,882 | Oct 5 | Warner Bros. | false |
| 22 | In Bruges | - | - | - | $196,802 | 232 | $7,800,824 | Feb 8 | Focus Features | false |
| 23 | The Pirates Who Don't Do Anything | - | - | - | $171,990 | 1,340 | $12,981,269 | Jan 11 | Universal Pictures | false |
| 24 | Enchanted | - | - | - | $160,374 | 3,730 | $127,807,262 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 25 | The Diving Bell and the Butterfly | - | - | - | $73,691 | 213 | $6,003,227 | Nov 30 | Miramax | false |
| 26 | Strange Wilderness | - | - | - | $60,178 | 1,211 | $6,575,282 | Feb 1 | Paramount Classics | false |
| 27 | U2 3D | - | - | - | $59,381 | 686 | $10,363,341 | Jan 23 | National Geographic Entertainment | false |
| 28 | The Savages | - | - | - | $58,071 | 201 | $6,623,082 | Nov 28 | - | false |
| 29 | I Am Legend | - | - | - | $50,572 | 3,648 | $256,393,010 | Dec 14 | Warner Bros. | false |
| 30 | Diary of the Dead | - | - | - | $42,485 | 48 | $958,961 | Feb 15 | Third Rail Releasing | false |
| 31 | Charlie Wilson's War | - | - | - | $41,375 | 2,594 | $66,661,095 | Dec 21 | Universal Pictures | false |
| 32 | P.S. I Love You | - | - | - | $36,611 | 2,471 | $53,695,808 | Dec 21 | Warner Bros. | false |
| 33 | Sweeney Todd: The Demon Barber of Fleet Street | - | - | - | $36,593 | 1,507 | $52,898,073 | Dec 21 | DreamWorks | false |
| 34 | The Kite Runner | - | - | - | $36,037 | 715 | $15,800,078 | Dec 14 | Paramount Vantage | false |
| 35 | First Sunday | - | - | - | $29,077 | 2,213 | $37,931,869 | Jan 11 | Screen Gems | false |
| 36 | Deep Sea | - | - | - | $22,742 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 37 | The Great Debaters | - | - | - | $21,079 | 1,290 | $30,236,407 | Dec 25 | - | false |
| 38 | Mad Money | - | - | - | $18,093 | 2,470 | $20,668,843 | Jan 18 | Overture Films | false |
| 39 | The Orphanage | - | - | - | $17,491 | 707 | $7,161,284 | Dec 28 | Picturehouse | false |
| 40 | How She Move | - | - | - | $15,282 | 1,531 | $7,070,641 | Jan 25 | Paramount Vantage | false |
| 41 | Caramel | - | - | - | $12,921 | 50 | $1,055,580 | Feb 1 | Roadside Attractions | false |
| 42 | Into the Wild | - | - | - | $12,237 | 660 | $18,354,356 | Sep 21 | Paramount Vantage | false |
| 43 | I'm Not There | - | - | - | $11,544 | 149 | $4,017,609 | Nov 21 | The Weinstein Company | false |
| 44 | August Rush | - | - | - | $10,536 | 2,310 | $31,664,162 | Nov 21 | Warner Bros. | false |
| 45 | The Mist | - | - | - | $9,624 | 2,423 | $25,594,957 | Nov 21 | - | false |
| 46 | Mr. Magorium's Wonder Emporium | - | - | - | $9,515 | 3,168 | $32,061,555 | Nov 16 | Twentieth Century Fox | false |
| 47 | Blade Runner The Final Cut (2007 re-release) | - | - | - | $7,142 | 20 | $1,548,502 | Oct 5 | Warner Bros. | false |
| 48 | Aliens vs. Predator: Requiem | - | - | - | $5,815 | 2,617 | $41,797,066 | Dec 25 | Twentieth Century Fox | false |
| 49 | Awake | - | - | - | $3,704 | 2,023 | $14,377,198 | Nov 30 | - | false |
| 50 | One Missed Call | - | - | - | $3,110 | 2,240 | $26,890,041 | Jan 4 | Warner Bros. | false |
| 51 | Lars and the Real Girl | - | - | - | $2,980 | 321 | $5,972,884 | Oct 12 | Metro-Goldwyn-Mayer (MGM) | false |
| 52 | Teeth | - | - | - | $2,607 | 16 | $347,578 | Jan 18 | Roadside Attractions | false |
| 53 | Wild West Comedy Show: 30 Days & 30 Nights - Hollywood to the Heartland | - | - | - | $2,399 | 962 | $603,894 | Feb 8 | Picturehouse | false |
| 54 | Cassandra's Dream | - | - | - | $1,954 | 107 | $973,018 | Jan 18 | The Weinstein Company | false |
| 55 | Shoot Down | - | - | - | $420 | 21 | $74,421 | Jan 25 | Magic Lamp | false |
| 56 | In the Valley of Elah | - | - | - | $121 | 978 | $6,777,741 | Sep 14 | Warner Independent Pictures (WIP) | false |
| 57 | Bella | - | - | - | $57 | 457 | $8,070,537 | Oct 26 | Roadside Attractions | false |
