| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Tangled | - | - | - | $21,608,891 | 3,603 | $200,821,936 | Nov 24 | Walt Disney Studios Motion Pictures | false |
| 2 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $17,018,475 | 4,125 | $295,983,305 | Nov 19 | Warner Bros. | false |
| 3 | Burlesque | - | - | - | $6,130,061 | 3,037 | $39,440,655 | Nov 24 | Screen Gems | false |
| 4 | Unstoppable | - | - | - | $5,970,194 | 3,261 | $81,562,942 | Nov 12 | Twentieth Century Fox | false |
| 5 | Love & Other Drugs | - | - | - | $5,652,810 | 2,458 | $32,367,005 | Nov 24 | Twentieth Century Fox | false |
| 6 | Megamind | - | - | - | $4,936,851 | 3,949 | $148,415,853 | Nov 5 | DreamWorks | false |
| 7 | Due Date | - | - | - | $4,133,286 | 3,365 | $100,539,043 | Nov 5 | Warner Bros. | false |
| 8 | Faster | - | - | - | $3,934,600 | 2,470 | $23,240,020 | Nov 24 | CBS Films | false |
| 9 | The Warrior's Way | - | - | - | $3,048,665 | 1,622 | $5,666,340 | Dec 3 | Relativity Media | false |
| 10 | The Next Three Days | - | - | - | $2,570,908 | 2,564 | $21,148,651 | Nov 19 | Lionsgate | false |
| 11 | Morning Glory | - | - | - | $1,681,759 | 2,544 | $31,011,732 | Nov 10 | Paramount Pictures | false |
| 12 | 127 Hours | - | - | - | $1,619,138 | 916 | $18,335,230 | Nov 5 | Fox Searchlight Pictures | false |
| 13 | Black Swan | - | - | - | $1,443,809 | 2,407 | $106,954,678 | Dec 3 | Fox Searchlight Pictures | false |
| 14 | Fair Game | - | - | - | $970,358 | 436 | $9,540,691 | Nov 5 | Summit Entertainment | false |
| 15 | Red | - | - | - | $750,940 | 3,349 | $90,380,162 | Oct 15 | Summit Entertainment | false |
| 16 | For Colored Girls | - | - | - | $444,403 | 2,127 | $37,729,698 | Nov 5 | Lionsgate | false |
| 17 | Skyline | - | - | - | $436,855 | 2,883 | $21,393,620 | Nov 12 | Universal Pictures | false |
| 18 | The Social Network | - | - | - | $404,456 | 2,921 | $96,962,694 | Oct 1 | Sony Pictures Releasing | false |
| 19 | The King's Speech | - | - | - | $324,515 | 2,584 | $135,453,143 | Nov 26 | The Weinstein Company | false |
| 20 | Secretariat | - | - | - | $256,739 | 3,108 | $59,713,955 | Oct 8 | Walt Disney Studios Motion Pictures | false |
| 21 | The Girl Who Kicked the Hornet's Nest | - | - | - | $243,159 | 208 | $5,190,196 | Oct 29 | Music Box Films | false |
| 22 | Despicable Me | - | - | - | $216,975 | 3,602 | $251,639,815 | Jul 9 | Universal Pictures | false |
| 23 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $214,304 | 3,575 | $55,675,313 | Sep 24 | Warner Bros. | false |
| 24 | The Town | - | - | - | $202,909 | 2,935 | $92,186,262 | Sep 17 | Warner Bros. | false |
| 25 | Inside Job | - | - | - | $195,394 | 250 | $4,312,735 | Oct 8 | Sony Pictures Classics | false |
| 26 | Easy A | - | - | - | $138,473 | 2,974 | $58,401,464 | Sep 17 | Screen Gems | false |
| 27 | I Love You Phillip Morris | - | - | - | $112,520 | 100 | $2,037,459 | Dec 3 | Roadside Attractions | false |
| 28 | Hubble | - | - | - | $110,927 | 151 | $52,522,904 | Mar 19 | Warner Bros. | false |
| 29 | Jackass 3D | - | - | - | $110,580 | 3,139 | $117,229,692 | Oct 15 | Paramount Pictures | false |
| 30 | Life as We Know It | - | - | - | $102,958 | 3,150 | $53,374,681 | Oct 8 | Warner Bros. | false |
| 31 | Paranormal Activity 2 | - | - | - | $101,029 | 3,239 | $84,752,907 | Oct 22 | Paramount Pictures | false |
| 32 | The Polar Express 2010 IMAX Release | - | - | - | $80,505 | 17 | $672,796 | Dec 3 | Warner Bros. | false |
| 33 | You Again | - | - | - | $71,656 | 2,548 | $25,702,053 | Sep 24 | Walt Disney Studios Motion Pictures | false |
| 34 | Conviction 2010 Re-release | - | - | - | $67,695 | 672 | $6,783,129 | Oct 15 | Fox Searchlight Pictures | false |
| 35 | Inception | - | - | - | $67,426 | 3,792 | $292,576,195 | Jul 16 | Warner Bros. | false |
| 36 | The Nutcracker: The Untold Story | - | - | - | $60,771 | 115 | $195,459 | Nov 24 | Freestyle Releasing | false |
| 37 | Guzaarish | - | - | - | $58,265 | 108 | $1,017,335 | Nov 19 | UTV Motion Pictures | false |
| 38 | Break Ke Baad | - | - | - | $54,564 | 85 | $427,628 | Nov 24 | Reliance Big Pictures | false |
| 39 | Today's Special | - | - | - | $50,293 | 55 | $317,831 | Nov 19 | Vitagraph Films | false |
| 40 | Hereafter | - | - | - | $49,924 | 2,424 | $32,746,941 | Oct 15 | Warner Bros. | false |
| 41 | Waiting for Superman | - | - | - | $40,497 | 330 | $6,417,135 | Sep 24 | Paramount Vantage | false |
| 42 | Made in Dagenham | - | - | - | $37,275 | 89 | $1,095,369 | Nov 19 | Sony Pictures Classics | false |
| 43 | All Good Things 2010 Re-release | - | - | - | $37,172 | 35 | $582,024 | Dec 3 | Magnolia Pictures | false |
| 44 | Tamara Drewe | - | - | - | $37,062 | 59 | $560,391 | Oct 8 | Sony Pictures Classics | false |
| 45 | White Material | - | - | - | $35,028 | 21 | $304,020 | Nov 19 | IFC Films | false |
| 46 | Tiny Furniture | - | - | - | $31,216 | 21 | $391,674 | Nov 12 | IFC Films | false |
| 47 | You Will Meet a Tall Dark Stranger | - | - | - | $27,084 | 402 | $3,248,246 | Sep 22 | Sony Pictures Classics | false |
| 48 | The Salvation Poem | - | - | - | $26,248 | 30 | $914,818 | Aug 27 | CanZion Films | false |
| 49 | Under the Sea 3D | - | - | - | $25,734 | 108 | $36,262,926 | Feb 13 | Warner Bros. | false |
| 50 | Wall Street: Money Never Sleeps | - | - | - | $21,902 | 3,597 | $52,474,616 | Sep 24 | Twentieth Century Fox | false |
| 51 | Vision | - | - | - | $17,476 | 17 | $435,274 | Oct 13 | Zeitgeist Films | false |
| 52 | Mao's Last Dancer | - | - | - | $17,421 | 137 | $4,817,770 | Aug 20 | The Samuel Goldwyn Company | false |
| 53 | Nowhere Boy | - | - | - | $15,704 | 215 | $1,457,248 | Oct 8 | The Weinstein Company | false |
| 54 | Howl | - | - | - | $15,378 | 29 | $617,334 | Sep 24 | Oscilloscope | false |
| 55 | Night Catches Us | - | - | - | $13,562 | 9 | $76,185 | Dec 3 | Magnolia Pictures | false |
| 56 | Space Station 3D | - | - | - | $13,189 | 64 | $93,383,953 | Apr 19 | IMAX | false |
| 57 | Leaving | - | - | - | $13,168 | 13 | $176,113 | Oct 1 | IFC Films | false |
| 58 | Four Lions | - | - | - | $13,105 | 18 | $304,616 | Nov 5 | Drafthouse Films | false |
| 59 | Kings of Pastry | - | - | - | $12,929 | 10 | $336,386 | Sep 15 | First Run | false |
| 60 | Stone | - | - | - | $12,664 | 125 | $1,810,078 | Oct 8 | Overture Films | false |
| 61 | Welcome to the Rileys | - | - | - | $12,191 | 11 | $158,898 | Oct 29 | The Samuel Goldwyn Company | false |
| 62 | Wild Target | - | - | - | $11,876 | 13 | $108,589 | Oct 29 | Freestyle Releasing | false |
| 63 | Saint Misbehavin': The Wavy Gravy Movie | - | - | - | $10,976 | 3 | $29,893 | Dec 3 | Argot Pictures | false |
| 64 | Never Let Me Go | - | - | - | $10,728 | 232 | $2,434,652 | Sep 15 | Fox Searchlight Pictures | false |
| 65 | Waste Land | - | - | - | $9,421 | 8 | $187,716 | Oct 29 | Arthouse Films | false |
| 66 | Rare Exports: A Christmas Tale | - | - | - | $9,281 | 21 | $236,347 | Dec 3 | Oscilloscope | false |
| 67 | Client 9 | - | - | - | $8,849 | 17 | $189,416 | Nov 5 | Magnolia Pictures | false |
| 68 | Marwencol | - | - | - | $8,501 | 6 | $112,036 | Oct 8 | The Cinema Guild | false |
| 69 | Breathless 2010 Re-release | - | - | - | $8,470 | 12 | $363,031 | May 28 | Rialto Pictures | false |
| 70 | Enter the Void | - | - | - | $8,416 | 13 | $336,467 | Sep 24 | IFC Films | false |
| 71 | Bhutto | - | - | - | $8,275 | 4 | $100,202 | Dec 3 | First Run | false |
| 72 | Monsters | - | - | - | $7,788 | 25 | $237,301 | Oct 29 | Magnolia Pictures | false |
| 73 | Sea Monsters: A Prehistoric Adventure | - | - | - | $6,825 | 252 | $23,746,066 | Oct 5 | National Geographic Entertainment | false |
| 74 | What If... | - | - | - | $6,297 | 82 | $814,906 | Aug 20 | Five & Two Pictures | false |
| 75 | Undertow | - | - | - | $6,183 | 3 | $108,620 | Sep 17 | The Film Collaborative | false |
| 76 | The Tillman Story | - | - | - | $5,675 | 28 | $802,535 | Aug 20 | The Weinstein Company | false |
| 77 | Last Train Home | - | - | - | $5,390 | 14 | $288,328 | Sep 3 | Zeitgeist Films | false |
| 78 | The Wildest Dream | - | - | - | $4,857 | 21 | $898,137 | Aug 6 | National Geographic Entertainment | true |
| 79 | Budrus | - | - | - | $4,350 | 4 | $68,353 | Oct 8 | Balcony Releasing | false |
| 80 | Deep Sea | - | - | - | $3,912 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 81 | Get Low | - | - | - | $3,746 | 570 | $9,176,933 | Jul 30 | Sony Pictures Classics | false |
| 82 | Mesrine: Killer Instinct 2010 Re-release | - | - | - | $3,730 | 34 | $551,697 | Aug 27 | Music Box Films | false |
| 83 | Guy and Madeline on a Park Bench | - | - | - | $3,712 | 5 | $35,556 | Nov 5 | Variance Films | false |
| 84 | Carlos | - | - | - | $3,473 | 7 | $145,526 | Oct 15 | IFC Films | false |
| 85 | Let Me In | - | - | - | $2,735 | 2,042 | $12,134,935 | Oct 1 | Overture Films | false |
| 86 | Genius Within: The Inner Life of Glenn Gould | - | - | - | $2,705 | 9 | $167,508 | Sep 10 | Lorber Films | false |
| 87 | Heartbreaker | - | - | - | $2,573 | 43 | $504,030 | Sep 10 | IFC Films | false |
| 88 | Galapagos | - | - | - | $2,411 | 14 | $18,630,372 | Oct 29 | IMAX | false |
| 89 | Winter's Bone | - | - | - | $2,137 | 141 | $6,531,503 | Jun 11 | Roadside Attractions | false |
| 90 | Come Undone | - | - | - | $2,030 | 2 | $10,035 | Dec 3 | Film Movement | false |
| 91 | Strange Powers: Stephin Merritt and the Magnetic Fields | - | - | - | $1,990 | 5 | $68,719 | Oct 27 | Variance Films | false |
| 92 | William S. Burroughs: A Man Within | - | - | - | $1,932 | 4 | $46,380 | Nov 17 | Oscilloscope | false |
| 93 | Dogtooth | - | - | - | $1,883 | 5 | $110,248 | Jun 25 | Kino International | false |
| 94 | Jack Goes Boating | - | - | - | $1,822 | 90 | $541,992 | Sep 17 | Overture Films | false |
| 95 | Aftershock | - | - | - | $1,542 | 25 | $62,962 | Oct 29 | China Lion Film Distribution | false |
| 96 | Cool It | - | - | - | $1,493 | 43 | $62,713 | Nov 12 | Roadside Attractions | false |
| 97 | The Little Traitor | - | - | - | $1,463 | 5 | $402,088 | Oct 23 | - | false |
| 98 | Inspector Bellamy | - | - | - | $1,454 | 4 | $107,612 | Oct 29 | IFC Films | false |
| 99 | Mesrine: Public Enemy No. 1 2010 Re-release | - | - | - | $1,344 | 31 | $275,387 | Sep 3 | Music Box Films | false |
| 100 | My Dog Tulip | - | - | - | $1,277 | 5 | $246,574 | Sep 1 | New Yorker Films | false |
| 101 | Alamar | - | - | - | $1,202 | 3 | $61,613 | Jul 14 | Film Movement | false |
| 102 | The Legend of Pale Male | - | - | - | $1,083 | 4 | $38,083 | Nov 24 | Balcony Releasing | false |
| 103 | The Girl with the Dragon Tattoo | - | - | - | $1,012 | 202 | $10,095,170 | Mar 19 | Music Box Films | false |
| 104 | Mademoiselle Chambon | - | - | - | $855 | 16 | $531,685 | May 28 | Lorber Films | false |
| 105 | The Girl Who Played with Fire | - | - | - | $844 | 185 | $7,638,241 | Jul 9 | Music Box Films | false |
| 106 | Restrepo | - | - | - | $836 | 52 | $1,330,894 | Jun 25 | National Geographic Entertainment | false |
| 107 | Hideaway | - | - | - | $694 | 5 | $34,525 | Sep 10 | Strand Releasing | false |
| 108 | Animal Kingdom | - | - | - | $670 | 61 | $1,044,039 | Aug 13 | Sony Pictures Classics | false |
| 109 | Terkel in Trouble 2010 Re-release | - | - | - | $500 | 4 | $40,385 | Oct 15 | Indican Pictures | false |
| 110 | House | - | - | - | $457 | 7 | $209,765 | Jan 15 | Janus Films | false |
| 111 | A Woman, a Gun and a Noodle Shop | - | - | - | $391 | 23 | $190,946 | Sep 3 | Sony Pictures Classics | false |
| 112 | Nine Nation Animation | - | - | - | $371 | 2 | $38,382 | Sep 29 | The World According to Shorts | false |
| 113 | Lebanon | - | - | - | $260 | 23 | $368,088 | Aug 6 | Sony Pictures Classics | false |
| 114 | Monsieur Verdoux | - | - | - | $238 | 2 | $64,636 | Mar 14 | The Film Desk | false |
| 115 | The Kids Grow Up | - | - | - | $105 | 1 | $12,095 | Oct 29 | Shadow Distribution | false |
| 116 | Sweethearts of the Prison Rodeo | - | - | - | $90 | 2 | $5,922 | Sep 17 | Cinema Purgatorio | false |
| 117 | Ran 2010 Re-release | - | - | - | $69 | 4 | $124,673 | Feb 5 | Rialto Pictures | false |
| 118 | Zenith | - | - | - | $36 | 4 | $7,862 | Oct 1 | Cinema Purgatorio | false |
| 119 | Brutal Beauty: Tales of the Rose City Rollers | - | - | - | $6 | 2 | $9,677 | Jan 8 | Cinema Purgatorio | false |
