| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Paul Blart: Mall Cop | - | - | - | $39,234,238 | 3,206 | $146,336,178 | Jan 16 | Sony Pictures Releasing | false |
| 2 | Gran Torino | - | - | - | $25,606,399 | 3,045 | $148,095,302 | Dec 12 | Warner Bros. | false |
| 3 | My Bloody Valentine | - | - | - | $24,103,962 | 2,534 | $51,545,952 | Jan 16 | Lionsgate | false |
| 4 | Notorious | - | - | - | $23,393,472 | 1,641 | $36,843,682 | Jan 16 | Fox Searchlight Pictures | false |
| 5 | Hotel for Dogs | - | - | - | $22,865,512 | 3,271 | $73,034,460 | Jan 16 | DreamWorks | false |
| 6 | Bride Wars | - | - | - | $13,878,727 | 3,228 | $58,715,510 | Jan 9 | Twentieth Century Fox | false |
| 7 | The Unborn | - | - | - | $10,545,075 | 2,359 | $42,670,410 | Jan 9 | Universal Pictures | false |
| 8 | Defiance | - | - | - | $10,510,082 | 1,793 | $28,644,813 | Dec 31 | Paramount Vantage | false |
| 9 | Marley & Me | - | - | - | $7,514,652 | 3,505 | $143,153,751 | Dec 25 | Twentieth Century Fox | false |
| 10 | Slumdog Millionaire | - | - | - | $7,021,727 | 2,943 | $141,319,928 | Nov 12 | Fox Searchlight Pictures | false |
| 11 | The Curious Case of Benjamin Button | - | - | - | $6,585,296 | 2,988 | $127,509,326 | Dec 25 | Paramount Pictures | false |
| 12 | Bedtime Stories | - | - | - | $6,168,048 | 3,684 | $110,101,975 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 13 | Last Chance Harvey | - | - | - | $5,011,596 | 1,108 | $14,889,042 | Dec 25 | Overture Films | false |
| 14 | Valkyrie | - | - | - | $4,556,379 | 2,838 | $83,077,833 | Dec 25 | United Artists | false |
| 15 | Yes Man | - | - | - | $3,088,360 | 3,434 | $97,690,976 | Dec 19 | Warner Bros. | false |
| 16 | Not Easily Broken | - | - | - | $2,370,071 | 725 | $10,572,742 | Jan 9 | Screen Gems | false |
| 17 | Revolutionary Road | - | - | - | $2,158,979 | 1,077 | $22,911,480 | Dec 26 | Paramount Vantage | false |
| 18 | Twilight | - | - | - | $2,119,782 | 3,649 | $192,769,854 | Nov 21 | Summit Entertainment | false |
| 19 | The Wrestler | - | - | - | $2,044,246 | 776 | $26,238,243 | Dec 17 | Fox Searchlight Pictures | false |
| 20 | The Reader | - | - | - | $1,518,171 | 1,203 | $34,194,407 | Dec 10 | The Weinstein Company | false |
| 21 | Doubt | - | - | - | $1,474,755 | 1,287 | $33,446,470 | Dec 12 | Miramax | false |
| 22 | Seven Pounds | - | - | - | $1,412,836 | 2,758 | $69,951,824 | Dec 19 | Sony Pictures Releasing | false |
| 23 | The Tale of Despereaux | - | - | - | $1,026,795 | 3,107 | $50,877,145 | Dec 19 | Universal Pictures | false |
| 24 | Milk | - | - | - | $942,359 | 882 | $31,841,299 | Nov 26 | Focus Features | false |
| 25 | Frost/Nixon | - | - | - | $818,615 | 1,105 | $18,622,031 | Dec 5 | Universal Pictures | false |
| 26 | Madagascar: Escape 2 Africa | - | - | - | $687,452 | 4,065 | $180,010,950 | Nov 7 | DreamWorks | false |
| 27 | CC2C | - | - | - | $685,798 | 130 | $921,738 | Jan 16 | Warner Bros. | false |
| 28 | The Day the Earth Stood Still | - | - | - | $537,934 | 3,560 | $79,366,978 | Dec 12 | Twentieth Century Fox | false |
| 29 | Bolt | - | - | - | $489,735 | 3,654 | $114,053,579 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 30 | Quantum of Solace | - | - | - | $395,678 | 3,501 | $168,368,427 | Nov 14 | Sony Pictures Releasing | false |
| 31 | Australia | - | - | - | $345,509 | 2,721 | $49,554,002 | Nov 26 | Twentieth Century Fox | false |
| 32 | Four Christmases | - | - | - | $326,300 | 3,540 | $120,146,040 | Nov 26 | Warner Bros. | false |
| 33 | Che: Part One/Che: Part Two | - | - | - | $198,510 | 39 | $1,497,109 | Dec 12 | IFC Films | false |
| 34 | Beverly Hills Chihuahua | - | - | - | $174,438 | 3,239 | $94,514,402 | Oct 3 | Walt Disney Studios Motion Pictures | false |
| 35 | Rachel Getting Married | - | - | - | $126,401 | 391 | $12,796,841 | Oct 3 | Sony Pictures Classics | false |
| 36 | Role Models | - | - | - | $122,495 | 2,798 | $67,294,270 | Nov 7 | Universal Pictures | false |
| 37 | Vicky Cristina Barcelona | - | - | - | $102,289 | 726 | $23,216,709 | Aug 15 | Metro-Goldwyn-Mayer (MGM) | false |
| 38 | Waltz with Bashir | - | - | - | $97,628 | 208 | $2,283,849 | Dec 25 | Sony Pictures Classics | false |
| 39 | The Spirit | - | - | - | $91,350 | 2,509 | $19,806,188 | Dec 25 | Lionsgate | false |
| 40 | Sea Monsters: A Prehistoric Adventure | - | - | - | $88,371 | 252 | $23,746,066 | Oct 5 | National Geographic Entertainment | false |
| 41 | Happy-Go-Lucky | - | - | - | $71,824 | 202 | $3,512,016 | Oct 10 | Miramax | false |
| 42 | High School Musical 3: Senior Year | - | - | - | $70,238 | 3,626 | $90,559,416 | Oct 24 | Walt Disney Studios Motion Pictures | false |
| 43 | Let the Right One In | - | - | - | $67,778 | 53 | $2,122,065 | Oct 24 | Magnolia Pictures | false |
| 44 | I've Loved You So Long | - | - | - | $50,529 | 69 | $3,169,305 | Oct 24 | Sony Pictures Classics | false |
| 45 | Synecdoche, New York | - | - | - | $45,544 | 119 | $3,083,538 | Oct 24 | Sony Pictures Classics | false |
| 46 | The Secret Life of Bees | - | - | - | $43,403 | 1,630 | $37,770,162 | Oct 17 | Fox Searchlight Pictures | false |
| 47 | The Boy in the Striped Pajamas | - | - | - | $42,499 | 679 | $9,046,156 | Nov 7 | Miramax | false |
| 48 | Space Station 3D | - | - | - | $37,913 | 64 | $93,383,953 | Apr 19 | IMAX | false |
| 49 | Magnificent Desolation: Walking on the Moon | - | - | - | $37,635 | 82 | $34,137,524 | Sep 23 | IMAX | false |
| 50 | Ghajini | - | - | - | $33,597 | 83 | $2,430,627 | Dec 24 | Adlabs Films | false |
| 51 | Soul Men | - | - | - | $31,365 | 2,048 | $12,082,391 | Nov 7 | Metro-Goldwyn-Mayer (MGM) | false |
| 52 | Roving Mars | - | - | - | $23,686 | 27 | $10,407,978 | Jan 27 | Walt Disney Studios Motion Pictures | false |
| 53 | Zack and Miri Make a Porno | - | - | - | $23,193 | 2,735 | $31,457,946 | Oct 31 | The Weinstein Company | false |
| 54 | Made in U.S.A | - | - | - | $20,467 | 2 | $95,209 | Jan 9 | Rialto Pictures | false |
| 55 | Silent Light | - | - | - | $15,605 | 1 | $60,200 | Jan 7 | Palisades Tartan | false |
| 56 | Appaloosa | - | - | - | $14,475 | 1,290 | $20,211,394 | Sep 19 | Warner Bros. | false |
| 57 | A Christmas Tale | - | - | - | $14,225 | 52 | $1,060,922 | Nov 14 | IFC Films | false |
| 58 | The Haunting of Molly Hartley | - | - | - | $13,199 | 2,652 | $13,559,812 | Oct 31 | Freestyle Releasing | false |
| 59 | Deep Sea | - | - | - | $12,921 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 60 | Wendy and Lucy | - | - | - | $12,466 | 40 | $865,695 | Dec 10 | Oscilloscope | false |
| 61 | Owl and the Sparrow | - | - | - | $11,016 | 4 | $47,071 | Jan 16 | Wave Releasing | false |
| 62 | The Dark Knight | - | - | - | $9,856 | 4,366 | $533,345,358 | Jul 18 | Warner Bros. | false |
| 63 | Lola Montès | - | - | - | $9,146 | 4 | $120,306 | Oct 10 | Rialto Pictures | false |
| 64 | Nothing Like the Holidays | - | - | - | $9,084 | 1,671 | $7,503,736 | Dec 12 | Overture Films | false |
| 65 | Timecrimes | - | - | - | $8,586 | 7 | $39,127 | Dec 12 | Magnolia Pictures | false |
| 66 | Tell No One | - | - | - | $4,353 | 112 | $6,177,192 | Jul 2 | Music Box Films | false |
| 67 | Cherry Blossoms | - | - | - | $4,178 | 8 | $104,589 | Jan 16 | Strand Releasing | false |
| 68 | The Secret of the Grain | - | - | - | $4,040 | 3 | $86,356 | Dec 24 | IFC Films | false |
| 69 | Just Another Love Story | - | - | - | $3,263 | 3 | $45,835 | Jan 9 | Koch Lorber Films | false |
| 70 | U2 3D | - | - | - | $3,146 | 686 | $10,363,341 | Jan 23 | National Geographic Entertainment | false |
| 71 | Igor | - | - | - | $2,767 | 2,341 | $19,528,602 | Sep 19 | Metro-Goldwyn-Mayer (MGM) | false |
| 72 | The Betrayal | - | - | - | $2,130 | 3 | $41,271 | Nov 21 | The Cinema Guild | false |
| 73 | The Secrets | - | - | - | $2,075 | 9 | $122,094 | Nov 26 | Monterey Media | false |
| 74 | A Secret | - | - | - | $1,708 | 11 | $623,558 | Sep 5 | Strand Releasing | false |
| 75 | Otto; or, Up with Dead People | - | - | - | $1,692 | 2 | $11,295 | Nov 7 | Strand Releasing | false |
| 76 | Stranded | - | - | - | $1,600 | 7 | $89,473 | Oct 22 | Zeitgeist Films | false |
| 77 | How About You | - | - | - | $1,496 | 7 | $78,234 | Nov 14 | Strand Releasing | false |
| 78 | Harvard Beats Yale 29-29 | - | - | - | $1,460 | 13 | $268,431 | Nov 19 | Kino International | false |
| 79 | Monsieur Verdoux | - | - | - | $1,091 | 2 | $64,636 | Mar 14 | The Film Desk | false |
| 80 | Yonkers Joe | - | - | - | $790 | 2 | $8,286 | Jan 9 | Magnolia Pictures | false |
| 81 | The Beautiful Truth | - | - | - | $689 | 2 | $15,387 | Nov 14 | Cinema Libre Studio | false |
| 82 | Trouble the Water | - | - | - | $648 | 15 | $520,151 | Aug 22 | Zeitgeist Films | false |
| 83 | Were the World Mine | - | - | - | $380 | 4 | $123,789 | Oct 31 | SPEAK Productions | false |
| 84 | The Wild Child | - | - | - | $375 | 2 | $65,051 | Nov 7 | The Film Desk | false |
| 85 | The Village Barbershop | - | - | - | $120 | 2 | $2,359 | Jan 16 | Monterey Media | false |
