| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Shark Tale | - | - | - | $36,604,033 | 4,070 | $160,861,908 | Oct 1 | DreamWorks Distribution | false |
| 2 | Friday Night Lights | - | - | - | $22,375,955 | 3,004 | $61,255,921 | Oct 8 | Universal Pictures | false |
| 3 | Ladder 49 | - | - | - | $14,713,337 | 3,261 | $74,541,707 | Oct 1 | Walt Disney Studios Motion Pictures | false |
| 4 | Taxi Original Release | - | - | - | $13,390,794 | 3,001 | $36,611,066 | Oct 6 | 20th Century Fox | false |
| 5 | The Forgotten | - | - | - | $8,539,769 | 3,144 | $67,133,509 | Sep 24 | Revolution Studios | false |
| 6 | Raise Your Voice | - | - | - | $4,606,000 | 2,521 | $10,411,980 | Oct 8 | New Line Cinema | true |
| 7 | Sky Captain and the World of Tomorrow | - | - | - | $2,645,812 | 3,170 | $37,762,677 | Sep 17 | Paramount Pictures | false |
| 8 | Resident Evil: Apocalypse | - | - | - | $1,424,051 | 3,284 | $51,201,453 | Sep 10 | Screen Gems | false |
| 9 | Napoleon Dynamite | - | - | - | $1,199,959 | 1,027 | $44,540,956 | Jun 11 | Fox Searchlight Pictures | false |
| 10 | Woman Thou Art Loosed | - | - | - | $1,147,836 | 521 | $6,879,730 | Oct 1 | Magnolia Pictures | true |
| 11 | Mr. 3000 | - | - | - | $1,100,079 | 2,736 | $21,811,187 | Sep 17 | Walt Disney Studios Motion Pictures | false |
| 12 | I Heart Huckabees | - | - | - | $1,046,678 | 901 | $12,785,432 | Oct 1 | Fox Searchlight Pictures | false |
| 13 | Cellular | - | - | - | $954,077 | 2,763 | $32,003,620 | Sep 10 | New Line Cinema | true |
| 14 | Wimbledon | - | - | - | $815,840 | 2,039 | $17,001,133 | Sep 17 | Universal Pictures | false |
| 15 | First Daughter | - | - | - | $700,605 | 2,280 | $9,055,921 | Sep 24 | 20th Century Fox | false |
| 16 | Hero | - | - | - | $658,022 | 2,175 | $53,710,019 | Aug 27 | Miramax | true |
| 17 | Garden State | - | - | - | $651,109 | 813 | $26,782,316 | Jul 28 | Fox Searchlight Pictures | false |
| 18 | Without a Paddle | - | - | - | $616,060 | 2,756 | $58,169,327 | Aug 20 | Paramount Pictures | false |
| 19 | Collateral | - | - | - | $475,667 | 3,205 | $101,005,703 | Aug 6 | DreamWorks Distribution | false |
| 20 | The Bourne Supremacy | - | - | - | $452,095 | 3,304 | $176,241,941 | Jul 23 | Universal Pictures | false |
| 21 | Spider-Man 2 | - | - | - | $345,666 | 4,166 | $373,585,825 | Jun 30 | Sony Pictures Releasing | false |
| 22 | Shaun of the Dead | - | - | - | $269,524 | 675 | $13,671,664 | Sep 24 | Rogue Pictures | false |
| 23 | The Motorcycle Diaries | - | - | - | $256,818 | 272 | $16,781,387 | Sep 24 | Focus Features | false |
| 24 | I, Robot | - | - | - | $166,164 | 3,494 | $144,801,023 | Jul 16 | 20th Century Fox | false |
| 25 | Alien vs. Predator | - | - | - | $116,403 | 3,401 | $80,282,231 | Aug 13 | 20th Century Fox | false |
| 26 | Anacondas: The Hunt for the Blood Orchid | - | - | - | $104,138 | 2,905 | $32,238,923 | Aug 27 | Screen Gems | false |
| 27 | NASCAR: The IMAX Experience | - | - | - | $68,132 | 73 | $21,583,831 | Mar 12 | Warner Bros. | false |
| 28 | The Manchurian Candidate | - | - | - | $63,446 | 2,867 | $65,955,630 | Jul 30 | Paramount Pictures | false |
| 29 | Ghost in the Shell 2: Innocence | - | - | - | $60,988 | 55 | $1,043,896 | Sep 17 | Go Fish Pictures | false |
| 30 | Harry Potter and the Prisoner of Azkaban | - | - | - | $53,279 | 3,855 | $249,541,069 | - | Warner Bros. | false |
| 31 | The Yes Men | - | - | - | $51,438 | 32 | $255,364 | Sep 24 | United Artists | false |
| 32 | The Last Shot | - | - | - | $42,736 | 40 | $464,275 | Sep 24 | Walt Disney Studios Motion Pictures | false |
| 33 | A Cinderella Story | - | - | - | $38,580 | 2,625 | $51,438,175 | Jul 16 | Warner Bros. | false |
| 34 | Intimate Strangers | - | - | - | $36,827 | 94 | $2,110,589 | Jul 30 | Paramount Classics | false |
| 35 | Catwoman | - | - | - | $36,405 | 3,117 | $40,202,379 | Jul 23 | Warner Bros. | false |
| 36 | Criminal | - | - | - | $34,064 | 90 | $929,233 | Sep 10 | Warner Independent Pictures (WIP) | false |
| 37 | Paparazzi | - | - | - | $32,839 | 2,153 | $15,714,234 | Sep 3 | 20th Century Fox | false |
| 38 | De-Lovely | - | - | - | $31,705 | 410 | $13,456,633 | Jul 2 | United Artists | false |
| 39 | Dodgeball: A True Underdog Story | - | - | - | $27,358 | 3,020 | $114,326,736 | Jun 18 | 20th Century Fox | false |
| 40 | Before Sunset | - | - | - | $24,616 | 204 | $5,820,649 | Jul 2 | Warner Independent Pictures (WIP) | false |
| 41 | Exorcist: The Beginning | - | - | - | $21,350 | 2,813 | $41,821,986 | Aug 20 | Warner Bros. | false |
| 42 | Around the Bend | - | - | - | $20,662 | 51 | $193,637 | Oct 8 | Warner Independent Pictures (WIP) | false |
| 43 | The Day After Tomorrow | - | - | - | $15,517 | 3,444 | $186,740,799 | May 28 | 20th Century Fox | false |
| 44 | Mean Creek | - | - | - | $13,615 | 49 | $603,951 | Aug 20 | Paramount Classics | false |
| 45 | We Don't Live Here Anymore | - | - | - | $12,985 | 190 | $2,041,014 | Aug 13 | Warner Independent Pictures (WIP) | false |
| 46 | I'll Sleep When I'm Dead | - | - | - | $3,014 | 19 | $360,759 | Jun 16 | Paramount Classics | false |
| 47 | Suspect Zero | - | - | - | $2,065 | 1,501 | $8,725,813 | Aug 27 | Paramount Pictures | false |
| 48 | A Home at the End of the World | - | - | - | $1,911 | 65 | $1,029,872 | Jul 23 | Warner Independent Pictures (WIP) | false |
