| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | National Treasure: Book of Secrets | - | - | - | $65,444,195 | 3,832 | $219,964,115 | Dec 21 | Walt Disney Studios Motion Pictures | false |
| 2 | I Am Legend | - | - | - | $47,685,378 | 3,648 | $256,393,010 | Dec 14 | Warner Bros. | false |
| 3 | Alvin and the Chipmunks | - | - | - | $38,609,310 | 3,499 | $217,326,974 | Dec 14 | Twentieth Century Fox | false |
| 4 | Charlie Wilson's War | - | - | - | $15,952,430 | 2,594 | $66,661,095 | Dec 21 | Universal Pictures | false |
| 5 | Sweeney Todd: The Demon Barber of Fleet Street | - | - | - | $13,635,390 | 1,507 | $52,898,073 | Dec 21 | DreamWorks | false |
| 6 | Aliens vs. Predator: Requiem | - | - | - | $9,515,615 | 2,617 | $41,797,066 | Dec 25 | Twentieth Century Fox | false |
| 7 | P.S. I Love You | - | - | - | $9,283,468 | 2,471 | $53,695,808 | Dec 21 | Warner Bros. | false |
| 8 | The Golden Compass | - | - | - | $6,837,077 | 3,528 | $70,107,728 | Dec 7 | New Line Cinema | true |
| 9 | Juno | - | - | - | $6,817,494 | 2,534 | $143,495,265 | Dec 5 | Fox Searchlight Pictures | false |
| 10 | Walk Hard: The Dewey Cox Story | - | - | - | $6,257,174 | 2,650 | $18,317,151 | Dec 21 | Sony Pictures Releasing | false |
| 11 | Enchanted | - | - | - | $6,235,069 | 3,730 | $127,807,262 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 12 | The Great Debaters | - | - | - | $3,639,116 | 1,290 | $30,236,407 | Dec 25 | Metro-Goldwyn-Mayer (MGM) | false |
| 13 | Atonement | - | - | - | $2,900,722 | 1,400 | $50,927,067 | Dec 7 | Focus Features | false |
| 14 | No Country for Old Men | - | - | - | $2,776,355 | 2,037 | $74,283,625 | Nov 9 | Miramax | false |
| 15 | The Water Horse | - | - | - | $2,385,644 | 2,777 | $40,946,255 | Dec 25 | Revolution Studios | false |
| 16 | The Kite Runner | - | - | - | $1,957,563 | 715 | $15,800,078 | Dec 14 | Paramount Vantage | false |
| 17 | The Perfect Holiday | - | - | - | $1,344,120 | 1,307 | $5,812,781 | Dec 12 | Yari Film Group Releasing | false |
| 18 | This Christmas | - | - | - | $1,338,517 | 1,921 | $49,121,934 | Nov 21 | Screen Gems | false |
| 19 | Fred Claus | - | - | - | $1,195,236 | 3,603 | $72,006,777 | Nov 9 | Warner Bros. | false |
| 20 | August Rush | - | - | - | $647,475 | 2,310 | $31,664,162 | Nov 21 | Warner Bros. | false |
| 21 | Bee Movie | - | - | - | $567,949 | 3,984 | $126,631,277 | Nov 2 | DreamWorks | false |
| 22 | Beowulf | - | - | - | $539,831 | 3,249 | $82,280,579 | Nov 16 | Paramount Pictures | false |
| 23 | The Polar Express 2007 IMAX Release | - | - | - | $500,670 | 32 | $2,483,757 | Oct 5 | Warner Bros. | false |
| 24 | American Gangster | - | - | - | $463,240 | 3,110 | $130,164,645 | Nov 2 | Universal Pictures | false |
| 25 | The Savages | - | - | - | $392,704 | 201 | $6,623,082 | Nov 28 | Fox Searchlight Pictures | false |
| 26 | Hitman | - | - | - | $265,736 | 2,468 | $39,687,694 | Nov 21 | Twentieth Century Fox | false |
| 27 | Mr. Magorium's Wonder Emporium | - | - | - | $248,133 | 3,168 | $32,061,555 | Nov 16 | Twentieth Century Fox | false |
| 28 | Awake | - | - | - | $238,196 | 2,023 | $14,377,198 | Nov 30 | Metro-Goldwyn-Mayer (MGM) | false |
| 29 | The Diving Bell and the Butterfly | - | - | - | $202,942 | 213 | $6,003,227 | Nov 30 | Miramax | false |
| 30 | The Bucket List | - | - | - | $161,840 | 2,915 | $93,466,502 | Dec 25 | Warner Bros. | false |
| 31 | I'm Not There | - | - | - | $160,098 | 149 | $4,017,609 | Nov 21 | The Weinstein Company | false |
| 32 | Into the Wild | - | - | - | $140,597 | 660 | $18,354,356 | Sep 21 | Paramount Vantage | false |
| 33 | Margot at the Wedding | - | - | - | $101,036 | 121 | $1,959,420 | Nov 16 | Paramount Vantage | false |
| 34 | Days of Darkness | - | - | - | $87,739 | 68 | $1,491,525 | Dec 7 | Alliance Atlantis Vivafilm | false |
| 35 | Michael Clayton | - | - | - | $74,477 | 2,585 | $49,033,882 | Oct 5 | Warner Bros. | false |
| 36 | Dan in Real Life | - | - | - | $70,664 | 1,941 | $47,642,963 | Oct 26 | Walt Disney Studios Motion Pictures | false |
| 37 | The Game Plan | - | - | - | $63,508 | 3,342 | $90,648,202 | Sep 28 | Walt Disney Studios Motion Pictures | false |
| 38 | Lars and the Real Girl | - | - | - | $61,694 | 321 | $5,972,884 | Oct 12 | Metro-Goldwyn-Mayer (MGM) | false |
| 39 | Deep Sea | - | - | - | $54,148 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 40 | The Mist | - | - | - | $53,214 | 2,423 | $25,594,957 | Nov 21 | Metro-Goldwyn-Mayer (MGM) | false |
| 41 | Youth Without Youth | - | - | - | $41,602 | 18 | $244,397 | Dec 14 | Sony Pictures Classics | false |
| 42 | Starting Out in the Evening | - | - | - | $40,911 | 43 | $898,786 | Nov 23 | Roadside Attractions | false |
| 43 | The Darjeeling Limited | - | - | - | $39,601 | 698 | $11,902,715 | Sep 29 | Fox Searchlight Pictures | false |
| 44 | Bella | - | - | - | $39,226 | 457 | $8,070,537 | Oct 26 | Roadside Attractions | false |
| 45 | Gone Baby Gone | - | - | - | $39,187 | 1,713 | $20,300,218 | Oct 19 | Miramax | false |
| 46 | Persepolis | - | - | - | $37,118 | 536 | $4,445,756 | Dec 25 | Sony Pictures Classics | false |
| 47 | Lust, Caution | - | - | - | $32,900 | 143 | $4,604,982 | Sep 28 | Focus Features | false |
| 48 | Steep | - | - | - | $30,735 | 23 | $260,586 | Dec 21 | Sony Pictures Classics | false |
| 49 | Roving Mars | - | - | - | $19,999 | 27 | $10,407,978 | Jan 27 | Walt Disney Studios Motion Pictures | false |
| 50 | Blade Runner The Final Cut (2007 re-release) | - | - | - | $18,003 | 20 | $1,548,502 | Oct 5 | Warner Bros. | false |
| 51 | Lions for Lambs | - | - | - | $15,818 | 2,216 | $15,002,854 | Nov 9 | United Artists | false |
| 52 | Control | - | - | - | $9,196 | 29 | $872,252 | Oct 10 | The Weinstein Company | false |
| 53 | Death at a Funeral | - | - | - | $5,418 | 324 | $8,580,428 | Aug 17 | Metro-Goldwyn-Mayer (MGM) | false |
| 54 | The Assassination of Jesse James by the Coward Robert Ford | - | - | - | $4,856 | 301 | $3,909,149 | Sep 21 | Warner Bros. | false |
| 55 | The Comebacks | - | - | - | $3,148 | 2,812 | $13,349,927 | Oct 19 | Fox Atomic | false |
| 56 | Joe Strummer: The Future Is Unwritten | - | - | - | $1,921 | 17 | $248,362 | Nov 2 | IFC Films | false |
| 57 | My Kid Could Paint That | - | - | - | $1,812 | 20 | $231,574 | Oct 5 | Sony Pictures Classics | false |
| 58 | Blonde Ambition | - | - | - | $1,771 | 8 | $6,422 | Dec 21 | First Look International | false |
| 59 | I Want Someone to Eat Cheese With | - | - | - | $1,724 | 14 | $194,568 | Sep 5 | IFC Films | false |
| 60 | Look | - | - | - | $1,578 | 3 | $16,136 | Dec 14 | Vitagraph Films | false |
| 61 | Jimmy Carter Man from Plains | - | - | - | $1,132 | 21 | $108,807 | Oct 26 | Sony Pictures Classics | false |
| 62 | Shotgun Stories | - | - | - | $1,056 | 4 | $46,026 | Dec 14 | International Film Circuit | false |
| 63 | Sleuth | - | - | - | $1,052 | 35 | $342,895 | Oct 12 | Sony Pictures Classics | false |
| 64 | Yiddish Theater: A Love Story | - | - | - | $646 | 3 | $40,182 | Nov 21 | New Love Films | false |
| 65 | For the Bible Tells Me So | - | - | - | $554 | 15 | $312,751 | Oct 5 | First Run | false |
| 66 | Flakes | - | - | - | $476 | 1 | $778 | Dec 19 | IFC Films | false |
| 67 | In the Valley of Elah | - | - | - | $460 | 978 | $6,777,741 | Sep 14 | Warner Independent Pictures (WIP) | false |
