| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Rio | - | - | - | $5,756,975 | 3,842 | $143,619,809 | Apr 15 | Twentieth Century Fox | false |
| 2 | Madea's Big Happy Family | - | - | - | $5,510,841 | 2,288 | $53,345,287 | Apr 22 | Lionsgate Films | false |
| 3 | Water for Elephants | - | - | - | $3,426,266 | 2,820 | $58,709,717 | Apr 22 | Twentieth Century Fox | false |
| 4 | Hop | - | - | - | $2,730,080 | 3,616 | $108,085,305 | Apr 1 | Universal Pictures | false |
| 5 | Scream 4 | - | - | - | $1,520,136 | 3,314 | $38,180,928 | Apr 15 | - | false |
| 6 | Hanna | - | - | - | $1,358,856 | 2,545 | $40,259,119 | Apr 8 | Focus Features | false |
| 7 | Source Code | - | - | - | $1,191,169 | 2,971 | $54,712,227 | Apr 1 | Summit Entertainment | false |
| 8 | Soul Surfer | - | - | - | $1,054,891 | 2,240 | $43,853,424 | Apr 8 | TriStar Pictures | false |
| 9 | Insidious | - | - | - | $1,031,011 | 2,419 | $54,009,150 | Apr 1 | FilmDistrict | false |
| 10 | African Cats | - | - | - | $971,290 | 1,224 | $15,428,747 | Apr 22 | Walt Disney Studios Motion Pictures | false |
| 11 | Arthur | - | - | - | $919,146 | 3,276 | $33,035,397 | Apr 8 | Warner Bros. | false |
| 12 | Limitless | - | - | - | $645,927 | 2,838 | $79,249,455 | Mar 18 | Relativity Media | false |
| 13 | The Conspirator | - | - | - | $507,327 | 849 | $11,538,204 | Apr 15 | Roadside Attractions | false |
| 14 | The Lincoln Lawyer | - | - | - | $459,112 | 2,707 | $58,009,200 | Mar 18 | Lionsgate Films | false |
| 15 | Your Highness | - | - | - | $434,725 | 2,772 | $21,596,445 | Apr 8 | Universal Pictures | false |
| 16 | Win Win | - | - | - | $245,973 | 388 | $10,179,275 | Mar 18 | - | false |
| 17 | Atlas Shrugged: Part I | - | - | - | $188,325 | 465 | $4,627,375 | Apr 15 | Rocky Mountain Pictures | false |
| 18 | Jane Eyre | - | - | - | $165,430 | 319 | $11,242,660 | Mar 11 | Focus Features | false |
| 19 | Born to Be Wild | - | - | - | $163,922 | 208 | $25,978,556 | Apr 8 | Warner Bros. | false |
| 20 | Diary of a Wimpy Kid: Rodrick Rules | - | - | - | $148,003 | 3,169 | $52,698,535 | Mar 25 | Twentieth Century Fox | false |
| 21 | Rango | - | - | - | $92,784 | 3,923 | $123,477,607 | Mar 4 | Paramount Pictures | false |
| 22 | Dum Maaro Dum | - | - | - | $87,473 | 101 | $564,489 | Apr 22 | - | false |
| 23 | Sucker Punch | - | - | - | $72,383 | 3,033 | $36,392,502 | Mar 25 | Warner Bros. | false |
| 24 | Paul | - | - | - | $61,250 | 2,806 | $37,412,945 | Mar 18 | Universal Pictures | false |
| 25 | The Adjustment Bureau | - | - | - | $53,915 | 2,847 | $62,495,645 | Mar 4 | Universal Pictures | false |
| 26 | Battle Los Angeles | - | - | - | $51,843 | 3,417 | $83,552,429 | Mar 11 | Sony Pictures Releasing | false |
| 27 | Just Go with It | - | - | - | $46,199 | 3,548 | $103,028,109 | Feb 11 | Sony Pictures Releasing | false |
| 28 | Red Riding Hood | - | - | - | $45,160 | 3,030 | $37,662,162 | Mar 11 | Warner Bros. | false |
| 29 | It's Not You, It's Me | - | - | - | $44,242 | 226 | $1,339,911 | Apr 8 | Lionsgate Films | false |
| 30 | The King's Speech PG-13 Version | - | - | - | $42,421 | 1,011 | $3,344,306 | Apr 1 | The Weinstein Company | false |
| 31 | Hubble | - | - | - | $31,002 | 151 | $52,522,904 | Mar 19 | Warner Bros. | false |
| 32 | Hall Pass | - | - | - | $30,011 | 2,950 | $45,060,734 | Feb 25 | Warner Bros. | false |
| 33 | Beastly | - | - | - | $22,138 | 1,959 | $27,865,571 | Mar 4 | CBS Films | false |
| 34 | Unknown | - | - | - | $21,394 | 3,043 | $63,686,397 | Feb 18 | Warner Bros. | false |
| 35 | Big Mommas: Like Father, Like Son | - | - | - | $14,252 | 2,821 | $37,915,414 | Feb 18 | Twentieth Century Fox | false |
| 36 | Justin Bieber: Never Say Never | - | - | - | $13,838 | 3,118 | $73,013,910 | Feb 11 | Paramount Pictures | false |
| 37 | True Grit | - | - | - | $10,880 | 3,464 | $171,243,005 | Dec 22 | Paramount Pictures | false |
| 38 | Kill the Irishman | - | - | - | $10,144 | 56 | $1,188,194 | Mar 11 | Anchor Bay Films | false |
| 39 | Thank You | - | - | - | $9,123 | 92 | $463,540 | Apr 8 | UTV Motion Pictures | false |
| 40 | Miral | - | - | - | $5,722 | 29 | $373,420 | Mar 25 | The Weinstein Company | false |
| 41 | Cedar Rapids | - | - | - | $5,492 | 462 | $6,861,102 | Feb 11 | - | false |
| 42 | Nostalgia for the Light | - | - | - | $3,754 | 6 | $163,962 | Jan 13 | Icarus Films | false |
| 43 | Biutiful | - | - | - | $3,608 | 191 | $5,101,237 | Jan 28 | Roadside Attractions | false |
| 44 | Diary of a Country Priest | - | - | - | $2,661 | 2 | $47,000 | Feb 25 | Rialto Pictures | false |
| 45 | Beautiful Darling | - | - | - | $2,501 | 3 | $34,096 | Apr 22 | Corinth Films | false |
| 46 | The Company Men | - | - | - | $1,350 | 277 | $4,441,272 | Jan 21 | The Weinstein Company | false |
| 47 | Black Swan | - | - | - | $1,103 | 2,407 | $106,954,678 | Dec 3 | - | false |
| 48 | Zokkomon | - | - | - | $671 | 24 | $3,000 | Apr 22 | UTV Motion Pictures | false |
| 49 | The Music Never Stopped | - | - | - | $582 | 33 | $258,223 | Mar 18 | Roadside Attractions | false |
| 50 | Meet Monica Velour | - | - | - | $244 | 4 | $33,042 | Apr 8 | Anchor Bay Films | false |
| 51 | Happythankyoumoreplease | - | - | - | $171 | 19 | $216,110 | Mar 4 | Anchor Bay Films | false |
