| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | Who Framed Roger Rabbit | $27,552,691 | - | - | - | Dec 2, 1988 | Walt Disney Pictures |
| 2 | Once Upon a Time... in Hollywood | $14,194,432 | 1,016 | $5,003,542 | 1,016 | Sep 19, 2019 | Warner Bros. |
| 3 | Hugo | $9,526,733 | 467 | $2,321,912 | 458 | Feb 2, 2012 | 01 Distribution |
| 4 | La La Land | $8,687,374 | 378 | $2,180,859 | 378 | Jan 26, 2017 | Andrea Leone Films |
| 5 | The Aviator | $7,157,934 | 438 | $2,759,240 | 438 | Jan 28, 2005 | 01 Distribution |
| 6 | Argo | $5,342,642 | 316 | $1,069,415 | 297 | Nov 8, 2012 | Warner Bros. |
| 7 | Birdman or (The Unexpected Virtue of Ignorance) | $5,021,620 | - | $929,183 | - | Feb 5, 2015 | - |
| 8 | Tropic Thunder | $4,624,397 | 297 | $1,832,212 | 297 | Oct 24, 2008 | Universal Pictures International (UPI) |
| 9 | America's Sweethearts | $3,701,440 | 408 | - | - | Feb 14, 2002 | - |
| 10 | The Artist | $3,528,704 | 127 | $88,409 | 22 | Dec 8, 2011 | BIM Distribuzione |
| 11 | Be Cool | $3,169,572 | 271 | $1,389,940 | 271 | Apr 15, 2005 | 20th Century Fox International |
| 12 | The Black Dahlia | $2,822,578 | 318 | $1,079,985 | 318 | Sep 29, 2006 | 01 Distribution |
| 13 | Somewhere | $2,783,084 | 240 | $612,209 | 240 | Sep 3, 2010 | Medusa Distribuzione |
| 14 | Grace of Monaco | $2,504,265 | 399 | $1,108,470 | 390 | May 14, 2014 | Lucky Red |
| 15 | Hail, Caesar! | $2,416,449 | 383 | $1,100,513 | 359 | Mar 10, 2016 | Universal Pictures International (UPI) |
| 16 | Drive | $2,396,019 | 324 | $703,316 | 324 | Sep 30, 2011 | 01 Distribution |
| 17 | Saving Mr. Banks | $1,921,920 | 232 | $692,451 | 222 | Feb 20, 2014 | Walt Disney Pictures |
| 18 | New Nightmare | $1,622,522 | 9 | - | - | Mar 3, 1995 | - |
| 19 | Nine | $1,604,773 | 250 | $756,184 | 250 | Jan 22, 2010 | 01 Distribution |
| 20 | What Just Happened | $1,350,455 | 275 | $686,888 | 275 | Apr 17, 2009 | Medusa Distribuzione |
| 21 | S1m0ne | $818,774 | 190 | - | - | Nov 15, 2002 | - |
| 22 | Mulholland Drive | $633,880 | 42 | - | - | Feb 15, 2002 | - |
| 23 | Seven Psychopaths | $568,748 | 138 | $316,714 | 138 | Nov 15, 2012 | Moviemax |
| 24 | Hitchcock | $378,643 | 72 | $112,901 | 20 | Apr 4, 2013 | 20th Century Fox International |
| 25 | State and Main | $323,801 | 28 | - | - | May 31, 2002 | - |
| 26 | This Is the End | $259,214 | 140 | $116,915 | 140 | Jul 18, 2013 | - |
| 27 | Stuck on You | $249,724 | 90 | $162,951 | 90 | Apr 16, 2004 | - |
| 28 | The Majestic | $205,934 | 50 | - | - | May 10, 2002 | - |
| 29 | Funny People | $196,082 | 4 | $146,397 | - | Oct 16, 2009 | United International Pictures |
| 30 | Full Frontal | $195,939 | 96 | - | - | Sep 20, 2002 | - |
| 31 | The Disaster Artist | $167,000 | 62 | $92,226 | 62 | Feb 22, 2018 | Warner Bros. |
| 32 | Trumbo | $163,429 | 53 | $100,202 | 53 | Feb 11, 2016 | Eagle Pictures |
| 33 | Ararat | $66,752 | 15 | - | - | Apr 30, 2003 | - |
| 34 | Sex Is Comedy | $51,420 | 13 | - | - | Jan 3, 2003 | - |
| 35 | Jay and Silent Bob Strike Back | $10,843 | 19 | - | - | Jun 14, 2002 | - |
| 36 | Win a Date with Tad Hamilton! | $9,855 | - | - | - | Jul 23, 2004 | - |
| 37 | An Alan Smithee Film: Burn Hollywood Burn | $7,071 | 1 | $2,117 | 1 | Jan 28, 2011 | Medusa Distribuzione |
