| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | The Hangover Part II | $1,600,947 | 39 | $506,488 | 39 | Jun 2, 2011 | Warner Bros. |
| 2 | Neighbors | $882,712 | 87 | $394,867 | 87 | May 15, 2014 | Edko Films |
| 3 | Blockers | $781,487 | 34 | - | - | May 24, 2018 | Universal Pictures International (UPI) |
| 4 | The Hangover | $720,509 | 24 | $193,101 | 24 | Jul 30, 2009 | Warner Bros. |
| 5 | 22 Jump Street | $562,647 | 65 | $309,368 | 65 | Aug 28, 2014 | Sony Pictures Releasing |
| 6 | Rough Night | $561,122 | 71 | $196,021 | 71 | Jul 27, 2017 | Sony Pictures Releasing |
| 7 | Good Boys | $519,989 | 39 | - | - | Sep 5, 2019 | Universal Pictures International (UPI) |
| 8 | Scary Movie 2 | $502,831 | 26 | - | - | Sep 13, 2001 | - |
| 9 | Wedding Crashers | $349,573 | 26 | - | - | Jan 5, 2006 | Golden Scene |
| 10 | American Pie 2 | $323,777 | 26 | - | - | Nov 1, 2001 | - |
| 11 | Jackass 3D | $311,492 | 10 | $87,176 | 10 | Nov 11, 2010 | Intercontinental Film Distributors (HK) |
| 12 | American Wedding | $300,219 | 28 | - | - | Oct 23, 2003 | Pro Vision |
| 13 | Bad Teacher | $215,623 | 25 | $142,122 | 25 | Sep 1, 2011 | Sony Pictures Releasing |
| 14 | Bridesmaids | $212,242 | 10 | $103,433 | 10 | Sep 15, 2011 | Edko Films |
| 15 | 40 Days and 40 Nights | $199,270 | - | - | - | May 30, 2002 | - |
| 16 | Knocked Up | $91,219 | 4 | $29,511 | 4 | Oct 18, 2007 | Edko Films |
| 17 | 21 & Over | $90,242 | 24 | $45,739 | 24 | May 23, 2013 | Edko Films |
| 18 | Van Wilder | $62,268 | - | - | - | Sep 5, 2002 | - |
| 19 | Sex Drive | $1,069 | 1 | $1,069 | 1 | Mar 26, 2009 | Deltamac Co. |
