| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | Transformers: Revenge of the Fallen | $402,111,870 | 4,293 | $108,966,307 | 4,234 | Jun 24, 2009 | DreamWorks |
| 2 | Transformers: Dark of the Moon | $352,390,543 | 4,088 | $97,852,865 | 4,088 | Jun 29, 2011 | DreamWorks |
| 3 | Transformers | $319,246,193 | 4,050 | $70,502,384 | 4,011 | Jul 3, 2007 | DreamWorks |
| 4 | Transformers: Age of Extinction | $245,439,076 | 4,233 | $100,038,390 | 4,233 | Jun 27, 2014 | Paramount Pictures |
| 5 | Alvin and the Chipmunks: The Squeakquel | $219,614,612 | 3,747 | $48,875,415 | 3,700 | Dec 23, 2009 | Twentieth Century Fox |
| 6 | Alvin and the Chipmunks | $217,326,974 | 3,499 | $44,307,417 | 3,475 | Dec 14, 2007 | Twentieth Century Fox |
| 7 | Scooby-Doo | $153,294,164 | 3,447 | $54,155,312 | 3,447 | Jun 14, 2002 | Warner Bros. |
| 8 | The Smurfs | $142,614,158 | 3,427 | $35,611,637 | 3,395 | Jul 29, 2011 | Sony Pictures Releasing |
| 9 | Alvin and the Chipmunks: Chipwrecked | $133,110,742 | 3,734 | $23,244,744 | 3,723 | Dec 16, 2011 | Twentieth Century Fox |
| 10 | The Last Airbender | $131,772,187 | 3,203 | $40,325,019 | 3,169 | Jul 1, 2010 | Paramount Pictures |
| 11 | The Flintstones | $130,531,208 | 2,594 | $29,688,730 | 2,498 | May 27, 1994 | Universal Pictures |
| 12 | Transformers: The Last Knight | $130,168,683 | 4,132 | $44,680,073 | 4,069 | Jun 21, 2017 | Paramount Pictures |
| 13 | Bumblebee | $127,195,589 | 3,597 | $21,654,047 | 3,550 | Dec 21, 2018 | Paramount Pictures |
| 14 | George of the Jungle | $105,263,257 | 2,616 | $16,540,791 | 2,506 | Jul 18, 1997 | Walt Disney Studios Motion Pictures |
| 15 | Casper | $100,439,549 | 2,757 | $16,840,385 | 2,714 | May 26, 1995 | Universal Pictures |
| 16 | Yogi Bear | $100,246,011 | 3,515 | $16,411,322 | 3,515 | Dec 17, 2010 | Warner Bros. |
| 17 | Inspector Gadget | $97,403,112 | 2,877 | $21,889,138 | 2,814 | Jul 23, 1999 | Walt Disney Studios Motion Pictures |
| 18 | Alvin and the Chipmunks: The Road Chip | $85,886,987 | 3,705 | $14,287,159 | 3,653 | Dec 18, 2015 | Twentieth Century Fox |
| 19 | Scooby-Doo 2: Monsters Unleashed | $84,216,833 | 3,312 | $29,438,331 | 3,312 | Mar 26, 2004 | Warner Bros. |
| 20 | Garfield: The Movie | $75,369,589 | 3,150 | $21,727,611 | 3,094 | Jun 11, 2004 | Twentieth Century Fox |
| 21 | The Smurfs 2 | $71,017,784 | 3,867 | $17,548,389 | 3,866 | Jul 31, 2013 | Sony Pictures Releasing |
| 22 | Dora and the Lost City of Gold | $60,477,943 | 3,735 | $17,431,588 | 3,735 | Aug 9, 2019 | Paramount Pictures |
| 23 | Popeye | $49,823,037 | 901 | $6,310,520 | 901 | Dec 12, 1980 | Paramount Pictures |
| 24 | Fat Albert | $48,116,322 | 2,744 | $10,021,510 | 2,674 | Dec 25, 2004 | Twentieth Century Fox |
| 25 | Speed Racer | $43,945,766 | 3,606 | $18,561,337 | 3,606 | May 9, 2008 | Warner Bros. |
| 26 | Underdog | $43,760,605 | 3,013 | $11,585,121 | 3,013 | Aug 3, 2007 | Walt Disney Studios Motion Pictures |
| 27 | Richie Rich | $38,087,756 | 1,761 | $5,830,302 | 1,748 | Dec 21, 1994 | Warner Bros. |
| 28 | The Flintstones in Viva Rock Vegas | $35,268,275 | 3,125 | $10,518,435 | 3,040 | Apr 28, 2000 | Universal Pictures |
| 29 | Garfield: A Tail of Two Kitties | $28,426,747 | 2,981 | $7,288,977 | 2,946 | Jun 16, 2006 | Twentieth Century Fox |
| 30 | The Adventures of Rocky & Bullwinkle | $26,005,820 | 2,482 | $6,814,270 | 2,460 | Jun 30, 2000 | Universal Pictures |
| 31 | Æon Flux | $25,874,337 | 2,608 | $12,661,112 | 2,608 | Dec 2, 2005 | Paramount Pictures |
| 32 | Mr. Magoo | $21,437,192 | 1,857 | $5,233,631 | 1,857 | Dec 25, 1997 | Walt Disney Studios Motion Pictures |
| 33 | Josie and the Pussycats | $14,271,015 | 2,558 | $4,562,455 | 2,556 | Apr 11, 2001 | Universal Pictures |
| 34 | Bratz | $10,010,209 | 1,509 | $4,208,455 | 1,509 | Aug 3, 2007 | Lionsgate Films |
| 35 | Dudley Do-Right | $9,974,410 | 1,855 | $3,018,345 | 1,802 | Aug 27, 1999 | Universal Pictures |
| 36 | Thunderbirds | $6,880,917 | 2,062 | $2,766,810 | 2,057 | Jul 30, 2004 | Universal Pictures |
