| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | Despicable Me 2 | $368,065,385 | 4,003 | $83,517,315 | 3,997 | Jul 3, 2013 | Universal Pictures |
| 2 | Despicable Me | $251,639,815 | 3,602 | $56,397,125 | 3,476 | Jul 9, 2010 | Universal Pictures |
| 3 | Three Men and a Baby | $167,780,960 | 1,813 | $10,384,392 | 1,006 | Nov 25, 1987 | Walt Disney Studios Motion Pictures |
| 4 | Big Daddy | $163,479,795 | 3,254 | $41,536,370 | 3,027 | Jun 25, 1999 | Sony Pictures Releasing |
| 5 | Cheaper by the Dozen | $138,614,544 | 3,307 | $27,557,647 | 3,298 | Dec 25, 2003 | Twentieth Century Fox |
| 6 | The Pacifier | $113,086,868 | 3,181 | $30,552,694 | 3,131 | Mar 4, 2005 | Walt Disney Studios Motion Pictures |
| 7 | Daddy Day Care | $104,297,061 | 3,472 | $27,623,580 | 3,370 | May 9, 2003 | Revolution Studios |
| 8 | Parenthood | $100,047,830 | 1,399 | $10,506,450 | 1,262 | Aug 2, 1989 | Universal Pictures |
| 9 | The Game Plan | $90,648,202 | 3,342 | $22,950,971 | 3,103 | Sep 28, 2007 | Walt Disney Studios Motion Pictures |
| 10 | Are We There Yet? | $82,674,398 | 2,810 | $18,575,214 | 2,709 | Jan 21, 2005 | Revolution Studios |
| 11 | Cheaper by the Dozen 2 | $82,571,173 | 3,211 | $9,309,387 | 3,175 | Dec 21, 2005 | Twentieth Century Fox |
| 12 | The Family Man | $75,793,305 | 2,441 | $10,554,960 | 2,388 | Dec 22, 2000 | Universal Pictures |
| 13 | RV | $71,726,025 | 3,651 | $16,414,767 | 3,639 | Apr 28, 2006 | Sony Pictures Releasing |
| 14 | Three Men and a Little Lady | $71,609,321 | 1,614 | $13,774,642 | 1,281 | Nov 21, 1990 | Walt Disney Studios Motion Pictures |
| 15 | Uncle Buck | $66,758,538 | 1,835 | $8,794,501 | 1,804 | Aug 18, 1989 | Universal Pictures |
| 16 | Mr. Mom | $64,783,827 | 1,362 | $947,197 | 126 | Jul 22, 1983 | Twentieth Century Fox |
| 17 | Jungle 2 Jungle | $59,927,618 | 2,340 | $12,812,047 | 2,316 | Mar 7, 1997 | Walt Disney Studios Motion Pictures |
| 18 | Problem Child | $53,470,891 | 1,769 | $10,026,900 | 1,714 | Jul 27, 1990 | Universal Pictures |
| 19 | Yours, Mine & Ours | $53,412,862 | 3,210 | $17,461,108 | 3,206 | Nov 23, 2005 | Paramount Pictures |
| 20 | Kicking & Screaming | $52,842,724 | 3,470 | $20,159,925 | 3,455 | May 13, 2005 | Universal Pictures |
| 21 | Are We Done Yet? | $49,662,533 | 2,944 | $14,262,724 | 2,877 | Apr 4, 2007 | Revolution Studios |
| 22 | Old Dogs | $49,492,060 | 3,425 | $16,894,511 | 3,425 | Nov 25, 2009 | Walt Disney Studios Motion Pictures |
| 23 | College Road Trip | $45,610,425 | 2,706 | $13,601,419 | 2,706 | Mar 7, 2008 | Walt Disney Studios Motion Pictures |
| 24 | Instructions Not Included | $44,467,206 | 978 | $7,846,426 | 348 | Aug 30, 2013 | Lionsgate Films |
| 25 | About a Boy | $41,385,278 | 1,756 | $8,557,630 | 1,207 | May 17, 2002 | Universal Pictures |
| 26 | Man of the House | $40,070,995 | 2,059 | $9,473,317 | 2,013 | Mar 3, 1995 | Walt Disney Studios Motion Pictures |
| 27 | That's My Boy | $36,931,089 | 3,030 | $13,453,714 | 3,030 | Jun 15, 2012 | Sony Pictures Releasing |
| 28 | Delivery Man | $30,664,106 | 3,036 | $7,944,977 | 3,036 | Nov 22, 2013 | Walt Disney Studios Motion Pictures |
| 29 | Fathers' Day | $28,598,376 | 2,507 | $8,776,159 | 2,482 | May 9, 1997 | Warner Bros. |
| 30 | Jersey Girl | $25,268,157 | 1,821 | $8,300,000 | 1,520 | Mar 26, 2004 | Miramax |
| 31 | Problem Child 2 | $25,104,700 | 1,500 | $5,372,880 | 1,464 | Jul 5, 1991 | Universal Pictures |
| 32 | Getting Even with Dad | $18,869,594 | 1,955 | $5,579,480 | 1,955 | Jun 17, 1994 | Metro-Goldwyn-Mayer (MGM) |
| 33 | My Baby's Daddy | $17,669,317 | 1,448 | $7,800,000 | 1,447 | Jan 9, 2004 | Miramax |
| 34 | Daddy Day Camp | $13,235,267 | 2,332 | $3,402,678 | 2,332 | Aug 8, 2007 | Revolution Studios |
| 35 | Playing for Keeps | $13,103,272 | 2,840 | $5,750,288 | 2,837 | Dec 7, 2012 | FilmDistrict |
| 36 | I Ought to Be in Pictures | $6,968,359 | 662 | $2,170,397 | 662 | Mar 26, 1982 | Twentieth Century Fox |
| 37 | Dutch | $4,603,929 | 1,232 | $1,867,201 | 1,232 | Jul 19, 1991 | Twentieth Century Fox |
| 38 | Tio Papi | $21,316 | 21 | $16,108 | 21 | Sep 6, 2013 | Active Fox Productions |
| 39 | The Stroller Strategy | $3,462 | 1 | $1,799 | 1 | Jun 14, 2013 | Rialto Pictures |
