| TD | YD | Release
| Daily | %± YD | %± LW | Theaters | Avg | To Date | Days | Distributor
| New This Day
| Estimated
|
|---|
| 1 | 1 | Black Widow | $7,368,262 | -29.3% | -58% | 4,275 | $1,723 | $131,609,167 | 10 | Walt Disney Studios Motion Pictures | false | false |
| 2 | 2 | F9: The Fast Saga | $2,335,240 | -24% | -33.7% | 3,368 | $693 | $154,892,670 | 24 | Universal Pictures | false | false |
| 3 | 3 | Escape Room: Tournament of Champions | $2,153,497 | -23% | - | 2,815 | $765 | $8,801,391 | 3 | Sony Pictures Releasing | false | false |
| 4 | 4 | The Boss Baby 2: Family Business | $1,316,995 | -30.6% | -49.3% | 3,449 | $381 | $44,651,760 | 17 | Universal Pictures | false | false |
| 5 | 5 | The Forever Purge | $1,239,255 | -21.9% | -44.5% | 2,735 | $453 | $35,866,540 | 17 | Universal Pictures | false | false |
| 6 | 6 | A Quiet Place Part II | $621,494 | -32% | -34% | 1,995 | $311 | $154,965,885 | 52 | Paramount Pictures | false | false |
| 7 | 7 | Roadrunner: A Film About Anthony Bourdain | $541,670 | -18.6% | - | 927 | $584 | $1,988,795 | 3 | Focus Features | false | false |
| 8 | 8 | Cruella | $310,150 | -36.3% | -49.1% | 1,175 | $263 | $83,483,327 | 52 | Walt Disney Studios Motion Pictures | false | false |
| 9 | 9 | Pig | $263,572 | -20.4% | - | 552 | $477 | $970,935 | 3 | Neon | false | false |
| 10 | 10 | Hitman's Wife's Bodyguard | $211,048 | -34.5% | -57.1% | 1,034 | $204 | $36,664,605 | 33 | Lionsgate Films | false | false |
| 11 | 11 | Peter Rabbit 2: The Runaway | $175,775 | -30.4% | -54.3% | 1,117 | $157 | $39,305,809 | 38 | Sony Pictures Releasing | false | false |
| 12 | 12 | Zola | $87,999 | -16% | -51% | 533 | $165 | $4,289,963 | 19 | A24 | false | false |
| 13 | 13 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $63,947 | -10% | -44.6% | 275 | $232 | $1,872,351 | 24 | Searchlight Pictures | false | false |
| 14 | 15 | Queen Bees | $19,940 | +6.8% | -20.3% | 123 | $162 | $1,778,910 | 38 | Gravitas Ventures | false | false |
| 15 | 14 | Spirit Untamed | $17,980 | -28.5% | -51.7% | 910 | $19 | $17,487,395 | 45 | Universal Pictures | false | false |
| 16 | 16 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $9,657 | -11.5% | -23.8% | 38 | $254 | $49,435,402 | 87 | FUNimation Entertainment | false | false |
| 17 | 18 | The Loneliest Whale: The Search for 52 | $6,875 | -4.6% | -49.7% | 71 | $96 | $83,201 | 10 | Bleecker Street Media | false | false |
| 18 | 20 | Werewolves Within | $4,524 | -22.9% | -40.7% | 46 | $98 | $557,413 | 24 | IFC Films | false | false |
| 19 | 21 | Dream Horse | $2,616 | -30.4% | -49.5% | 30 | $87 | $2,853,673 | 59 | Bleecker Street Media | false | false |
| 20 | 19 | Raya and the Last Dragon | $2,318 | -66.8% | -69.8% | 41 | $56 | $54,620,871 | 136 | Walt Disney Studios Motion Pictures | false | false |
| 21 | 22 | Wrath of Man | $2,292 | -34.6% | -41.2% | 45 | $50 | $27,454,233 | 73 | United Artists Releasing | false | false |
| 22 | 23 | The Swimming Pool 2021 Re-release | $1,941 | -38% | - | 4 | $485 | $127,330 | 66 | Rialto Distribution | false | false |
| 23 | 24 | The Red Circle 2021 Re-release | $1,887 | -24.6% | - | 5 | $377 | $45,987 | 24 | Rialto Pictures | false | false |
| 24 | 25 | Rita Moreno: Just a Girl Who Decided to Go for It | $1,678 | -5.9% | -26% | 16 | $104 | $257,983 | 31 | Roadside Attractions | false | false |
| 25 | 17 | Witnesses | $674 | -90.8% | +2.3% | 21 | $32 | $771,375 | 45 | Purdie Distribution | false | false |
| 26 | 26 | Casanova, Last Love | $530 | -26.4% | - | 6 | $88 | $3,090 | 5 | Cohen Media Group | false | false |
| 27 | 27 | The Ladykillers 2021 Re-release | $36 | -30.8% | - | 1 | $36 | $18,705 | 45 | Rialto Pictures | false | false |
