Domestic Box Office For Oct 6, 2010
| TD | YD | Release | Distributor | Daily | %± YD | %± LW | Theaters | Avg | To Date | Days |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | The Social Network | Sony Pictures Releasing | $1,902,659 | -18.6% | - | 2,771 | $686 | $28,743,563 | 6 |
| 2 | 2 | The Town | Warner Bros. | $828,343 | -14.1% | -36% | 2,935 | $282 | $66,664,325 | 20 |
| 3 | 3 | Wall Street: Money Never Sleeps | Twentieth Century Fox | $799,257 | -17.1% | -49.6% | 3,597 | $222 | $38,315,227 | 13 |
| 4 | 4 | Legend of the Guardians: The Owls of Ga'Hoole | Warner Bros. | $549,051 | -10.8% | -21.9% | 3,575 | $153 | $31,817,731 | 13 |
| 5 | 5 | Easy A | Screen Gems | $413,956 | -14.4% | -33.5% | 2,974 | $139 | $43,481,276 | 20 |
| 6 | 6 | You Again | Walt Disney Studios Motion Pictures | $399,712 | -16.2% | -32.2% | 2,548 | $156 | $17,842,323 | 13 |
| 7 | 7 | Case 39 | Paramount Vantage | $368,215 | -19.5% | - | 2,211 | $166 | $6,615,783 | 6 |
| 8 | 8 | Let Me In | Overture Films | $361,473 | -19.6% | - | 2,020 | $178 | $6,377,139 | 6 |
| 9 | 9 | Resident Evil: Afterlife | Screen Gems | $235,509 | -11.4% | -41.1% | 1,907 | $123 | $57,369,778 | 27 |
| 10 | 10 | Devil | Universal Pictures | $215,280 | -14.2% | -48.8% | 2,392 | $90 | $28,008,885 | 20 |
| 11 | 11 | Alpha and Omega | Lionsgate | $134,441 | -6% | -32.6% | 2,303 | $58 | $19,365,756 | 20 |
| 12 | 12 | Inception | Warner Bros. | $70,259 | -5.1% | -32.7% | 625 | $112 | $288,617,960 | 83 |
| 13 | 14 | Catfish | Rogue Pictures | $55,318 | -1.4% | -2.7% | 136 | $406 | $1,790,600 | 20 |
| 14 | 13 | Takers | Screen Gems | $53,926 | -7.1% | -53.1% | 773 | $69 | $56,331,063 | 41 |
| 15 | 15 | Waiting for 'Superman' | Paramount Vantage | $44,478 | -2.1% | +225.6% | 34 | $1,308 | $723,937 | 13 |
| 16 | 16 | Eat Pray Love | Sony Pictures Releasing | $40,944 | -7.6% | -51.8% | 398 | $102 | $79,827,225 | 55 |
| 17 | 18 | Hubble 3D | Warner Bros. | $33,057 | +7.5% | +5.8% | 60 | $550 | $16,250,002 | 202 |
| 18 | 17 | The Other Guys | Sony Pictures Releasing | $29,816 | -10.6% | -58.1% | 566 | $52 | $117,791,595 | 62 |
| 19 | 19 | Despicable Me | Universal Pictures | $27,780 | -7.7% | -8.9% | 463 | $60 | $246,179,755 | 90 |
| 20 | 21 | The Expendables | Lionsgate | $22,490 | -10.7% | -56.2% | 410 | $54 | $102,585,933 | 55 |
| 21 | 20 | The American | Focus Features | $21,395 | -16% | -77% | 374 | $57 | $35,269,243 | 36 |
| 22 | 22 | Machete | Twentieth Century Fox | $20,953 | -10.4% | -65.7% | 314 | $66 | $26,268,779 | 34 |
| 23 | 23 | Never Let Me Go | Fox Searchlight Pictures | $20,130 | -8.3% | -15.5% | 43 | $468 | $784,303 | 22 |
| 24 | 24 | Dinner for Schmucks | DreamWorks | $17,716 | -1.7% | -30.6% | 261 | $67 | $72,862,002 | 69 |
| 25 | 25 | Lottery Ticket | Warner Bros. | $14,669 | -9.7% | -1.2% | 302 | $48 | $24,292,926 | 48 |
| 26 | 27 | Buried | Lionsgate | $12,631 | -5.1% | +32.6% | 33 | $382 | $274,643 | 13 |
| 27 | 30 | Vampires Suck | Twentieth Century Fox | $12,268 | +8.8% | +6.6% | 261 | $47 | $36,398,643 | 50 |
| 28 | 26 | Nanny McPhee Returns | Universal Pictures | $12,025 | -15.5% | -36% | 481 | $25 | $28,561,640 | 48 |
| 29 | 28 | Jack Goes Boating | Overture Films | $12,008 | -3.8% | +23.6% | 78 | $153 | $305,463 | 20 |
| 30 | 29 | The Last Exorcism | Lionsgate | $10,816 | -7% | -53.9% | 307 | $35 | $41,022,885 | 41 |
| 31 | 32 | Scott Pilgrim vs. the World | Universal Pictures | $7,225 | -7.5% | -58.7% | 120 | $60 | $31,516,500 | 55 |
| 32 | 33 | The Virginity Hit | Sony Pictures Releasing | $6,859 | -7.7% | -81.5% | 434 | $15 | $556,792 | 13 |
| 33 | 38 | Under the Sea 3D | Warner Bros. | $6,824 | +47.1% | +28.4% | 18 | $379 | $24,354,416 | 601 |
| 34 | 34 | The Twilight Saga: Eclipse | Summit Entertainment | $6,671 | +11.3% | -35.7% | 83 | $80 | $300,430,812 | 99 |
| 35 | 37 | The Kids Are All Right | Focus Features | $6,331 | +31.5% | -23.9% | 64 | $98 | $20,749,048 | 90 |
| 36 | 36 | Winter's Bone | Roadside Attractions | $6,231 | +16.5% | -10% | 78 | $79 | $6,138,753 | 118 |
| 37 | 31 | Cats & Dogs: The Revenge of Kitty Galore | Warner Bros. | $6,065 | -32.3% | -27.5% | 188 | $32 | $43,454,718 | 69 |
| 38 | 35 | Piranha 3D | - | $4,942 | -11.9% | +53.4% | 95 | $52 | $24,915,987 | 48 |
| 39 | 40 | The Tillman Story | The Weinstein Company | $4,312 | +0.5% | -28.3% | 27 | $159 | $645,710 | 48 |
| 40 | 39 | Ramona and Beezus | Twentieth Century Fox | $3,939 | -13.6% | -13.6% | 161 | $24 | $25,985,387 | 76 |
| 41 | 42 | Going the Distance | Warner Bros. | $3,928 | -5.2% | -82% | 121 | $32 | $17,678,150 | 34 |
| 42 | 43 | The Concert | The Weinstein Company | $3,268 | +33.8% | -18.5% | 21 | $155 | $620,209 | 69 |
| 43 | 41 | Avatar 2010 Special Edition | Twentieth Century Fox | $3,161 | -24.4% | -33.9% | 19 | $166 | $10,521,624 | 41 |
| 44 | 44 | Flipped | Warner Bros. | $1,504 | -5% | -69.2% | 35 | $42 | $1,743,737 | 62 |
| 45 | 45 | Bran Nue Dae | Freestyle Releasing | $926 | -7.2% | -76.8% | 13 | $71 | $112,635 | 27 |
| 46 | 46 | The Disappearance of Alice Creed | Anchor Bay Films | $260 | -37.5% | -11.9% | 3 | $86 | $162,511 | 62 |
| 47 | 47 | Undertow | The Film Collaborative | $195 | -31.8% | -34.1% | 1 | $195 | $17,861 | 20 |
| 48 | 48 | Metal Messiah | - | $180 | +87.5% | - | 1 | $180 | $2,209 | 21 |