Domestic Box Office For May 6, 2010
| TD | YD | Release | Distributor | Daily | %± YD | %± LW | Theaters | Avg | To Date | Days |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | A Nightmare on Elm Street | Warner Bros. | $1,278,021 | -1.2% | - | 3,332 | $383 | $39,360,171 | 7 |
| 2 | 3 | The Back-up Plan | CBS Films | $507,241 | +5.2% | -37.1% | 3,280 | $154 | $25,070,469 | 14 |
| 3 | 4 | Date Night | Twentieth Century Fox | $494,759 | +9.4% | -27.5% | 3,093 | $159 | $75,554,468 | 28 |
| 4 | 2 | How to Train Your Dragon | DreamWorks | $477,265 | -3.5% | -38% | 3,426 | $139 | $194,333,493 | 42 |
| 5 | 5 | Clash of the Titans | Warner Bros. | $357,306 | -5.8% | -39.9% | 2,737 | $130 | $155,503,026 | 35 |
| 6 | 6 | The Losers | Warner Bros. | $346,480 | -5.4% | -43% | 2,936 | $118 | $19,649,617 | 14 |
| 7 | 7 | Kick-Ass | Lionsgate | $345,923 | +0.1% | -49.9% | 2,542 | $136 | $43,776,146 | 21 |
| 8 | 8 | Death at a Funeral | Screen Gems | $306,120 | +0.8% | -41.3% | 2,271 | $134 | $36,223,181 | 21 |
| 9 | 9 | Oceans 2010 Re-release | Walt Disney Studios Motion Pictures | $286,928 | +13.8% | -55.6% | 1,210 | $237 | $14,525,648 | 15 |
| 10 | 10 | Furry Vengeance | Summit Entertainment | $219,027 | +1.9% | - | 2,997 | $73 | $7,621,957 | 7 |
| 11 | - | Iron Man | Paramount Pictures | $192,025 | - | - | 1,105 | $173 | $318,604,126 | 735 |
| 12 | 11 | The Last Song | Walt Disney Studios Motion Pictures | $146,576 | +12.5% | -34.9% | 2,276 | $64 | $59,167,885 | 37 |
| 13 | 12 | Alice in Wonderland | Walt Disney Studios Motion Pictures | $109,870 | +0.5% | -29.6% | 1,050 | $104 | $330,145,228 | 63 |
| 14 | 13 | Hot Tub Time Machine | Metro-Goldwyn-Mayer (MGM) | $104,497 | +4% | -45.1% | 1,112 | $93 | $48,065,556 | 42 |
| 15 | 14 | Hubble 3D | Warner Bros. | $81,896 | +14.4% | +4% | 49 | $1,671 | $4,820,055 | 49 |
| 16 | 16 | The Bounty Hunter | Sony Pictures Releasing | $60,710 | +8.4% | -51% | 891 | $68 | $64,295,992 | 49 |
| 17 | 15 | City Island | Anchor Bay Films | $59,442 | <0.1% | +116.6% | 269 | $220 | $2,334,533 | 49 |
| 18 | 17 | Avatar | Twentieth Century Fox | $57,215 | +4.4% | -28.3% | 387 | $147 | $747,521,330 | 140 |
| 19 | 18 | Why Did I Get Married Too? | Lionsgate | $51,156 | +5.5% | -51% | 727 | $70 | $58,954,524 | 35 |
| 20 | 19 | Diary of a Wimpy Kid | Twentieth Century Fox | $36,935 | +7.2% | -44.2% | 1,166 | $31 | $61,052,308 | 49 |
| 21 | 20 | The Ghost Writer | Summit Entertainment | $31,636 | +6.5% | -28.1% | 336 | $94 | $14,641,723 | 77 |
| 22 | 22 | She's Out of My League | Paramount Pictures | $16,134 | +8.2% | +46.4% | 243 | $66 | $31,022,669 | 56 |
| 23 | 21 | Shutter Island | Paramount Pictures | $16,102 | +7.2% | -37.6% | 250 | $64 | $126,605,931 | 77 |
| 24 | 25 | Under the Sea 3D | Warner Bros. | $15,261 | +31.4% | -21.7% | 16 | $953 | $21,839,405 | 448 |
| 25 | 24 | Greenberg | Focus Features | $12,872 | +10.1% | -28.2% | 143 | $90 | $3,980,400 | 49 |
| 26 | 26 | Percy Jackson & the Olympians: The Lightning Thief | Twentieth Century Fox | $12,685 | +18.6% | -11.3% | 265 | $47 | $88,051,808 | 84 |
| 27 | 23 | The Joneses | Roadside Attractions | $12,597 | +2.7% | -56.9% | 67 | $188 | $1,292,384 | 21 |
| 28 | 28 | The Runaways | Apparition | $10,975 | +23.4% | -36.9% | 122 | $89 | $3,453,464 | 49 |
| 29 | 27 | The Crazies | Overture Films | $9,151 | -0.4% | -30.4% | 197 | $46 | $38,951,045 | 70 |
| 30 | 31 | Crazy Heart | Fox Searchlight Pictures | $8,561 | +18.7% | -1.8% | 118 | $72 | $39,360,040 | 142 |
| 31 | 29 | Letters to God | Vivendi Entertainment | $8,389 | +0.4% | -56.5% | 199 | $42 | $2,687,278 | 28 |
| 32 | 32 | Tooth Fairy | Twentieth Century Fox | $7,481 | +6.7% | -37.2% | 186 | $40 | $59,594,826 | 105 |
| 33 | 30 | Green Zone | Universal Pictures | $7,250 | -1% | -47.9% | 133 | $54 | $35,053,660 | 56 |
| 34 | 33 | Brooklyn's Finest | Overture Films | $6,672 | -4.3% | +297.9% | 146 | $45 | $27,090,691 | 63 |
| 35 | 34 | Cop Out | Warner Bros. | $6,193 | +6.1% | -34% | 141 | $43 | $44,786,789 | 70 |
| 36 | 35 | Our Family Wedding | Fox Searchlight Pictures | $4,918 | -10.3% | -20.1% | 98 | $50 | $19,917,812 | 56 |
| 37 | 38 | Remember Me | Summit Entertainment | $4,553 | +23.5% | -54.7% | 118 | $38 | $19,033,206 | 56 |
| 38 | 36 | The Square 2010 Re-release | Apparition | $4,525 | +2.2% | -1.5% | 24 | $188 | $192,989 | 28 |
| 39 | 37 | The Book of Eli | Warner Bros. | $4,398 | +9% | -35.4% | 77 | $57 | $94,797,969 | 112 |
| 40 | 39 | The Secret of Kells | GKIDS | $3,244 | +12.6% | -12.5% | 37 | $87 | $412,957 | 63 |
| 41 | 40 | Valentine's Day | Warner Bros. | $2,180 | +1% | -61.8% | 59 | $36 | $110,485,654 | 84 |
| 42 | 41 | The Blind Side | Warner Bros. | $1,427 | +19.5% | -51.3% | 46 | $31 | $255,935,011 | 168 |
| 43 | 42 | Breath Made Visible: Anna Halprin | Argot Pictures | $614 | +1.2% | -37.9% | 1 | $614 | $30,364 | 35 |
| 44 | 43 | That Evening Sun | Freestyle Releasing | $190 | -37.7% | -77.4% | 4 | $47 | $277,529 | 182 |
| 45 | 44 | After.Life | Anchor Bay Films | $142 | +31.5% | -46.8% | 2 | $71 | $108,595 | 28 |