| TD | YD | Release
| Distributor
| Daily | %± YD | %± LW | Theaters | Avg | To Date | Days | New This Day
| Estimated
|
|---|
| 1 | 2 | Inglourious Basterds | The Weinstein Company | $1,683,414 | -14.9% | -53% | 3,165 | $531 | $78,648,208 | 13 | - | false |
| 2 | 1 | The Final Destination | Warner Bros. | $1,678,241 | -24.1% | - | 3,121 | $537 | $33,531,007 | 6 | - | false |
| 3 | 3 | District 9 | TriStar Pictures | $896,065 | -17.1% | -47.3% | 3,180 | $281 | $93,386,686 | 20 | - | false |
| 4 | 4 | Halloween II | - | $794,019 | -26.4% | - | 3,025 | $262 | $19,314,905 | 6 | - | false |
| 5 | 5 | Julie & Julia | Sony Pictures Releasing | $727,600 | -11.6% | -37.2% | 2,503 | $290 | $72,896,782 | 27 | - | false |
| 6 | 6 | The Time Traveler's Wife | Warner Bros. | $581,125 | -16.8% | -43.7% | 2,961 | $196 | $49,756,923 | 20 | - | false |
| 7 | 7 | G.I. Joe: The Rise of Cobra | Paramount Pictures | $491,340 | -17.5% | -49.9% | 3,467 | $141 | $133,821,730 | 27 | - | false |
| 8 | 8 | Shorts | Warner Bros. | $266,471 | -23% | -52.1% | 3,105 | $85 | $14,167,774 | 13 | - | false |
| 9 | 9 | Taking Woodstock | Focus Features | $239,256 | -18.2% | +1,949.1% | 1,393 | $171 | $4,305,825 | 8 | - | false |
| 10 | 11 | 500 Days of Summer | Fox Searchlight Pictures | $205,431 | -11.7% | -26.3% | 909 | $225 | $25,847,727 | 48 | - | false |
| 11 | 12 | Harry Potter and the Half-Blood Prince | Warner Bros. | $197,003 | -10.9% | -49.3% | 1,508 | $130 | $294,904,348 | 50 | - | false |
| 12 | 10 | G-Force | Walt Disney Studios Motion Pictures | $186,586 | -23.1% | -57.7% | 1,926 | $96 | $112,440,771 | 41 | - | false |
| 13 | 13 | The Ugly Truth | Sony Pictures Releasing | $167,552 | -14.1% | -49.7% | 1,252 | $133 | $86,274,400 | 41 | - | false |
| 14 | 14 | Ponyo | Walt Disney Studios Motion Pictures | $142,110 | -14.2% | -44.1% | 880 | $161 | $11,510,023 | 20 | - | false |
| 15 | 15 | The Goods: Live Hard, Sell Hard | Paramount Vantage | $133,078 | -16.1% | -60% | 1,426 | $93 | $14,254,146 | 20 | - | false |
| 16 | 16 | Post Grad | Twentieth Century Fox | $120,303 | -21.5% | -56.2% | 1,959 | $61 | $5,718,348 | 13 | - | false |
| 17 | 17 | The Hangover | Warner Bros. | $115,207 | -2.4% | -26.7% | 801 | $143 | $270,582,232 | 90 | - | false |
| 18 | 18 | Transformers: Revenge of the Fallen | DreamWorks | $49,138 | -14.8% | -50.9% | 622 | $79 | $399,575,659 | 71 | - | false |
| 19 | 19 | Ice Age: Dawn of the Dinosaurs | Twentieth Century Fox | $35,787 | -30.3% | -55.7% | 432 | $82 | $193,384,067 | 64 | - | false |
| 20 | 21 | Orphan | Warner Bros. | $34,226 | -8.4% | -49.9% | 482 | $71 | $40,715,846 | 41 | - | false |
| 21 | 20 | Adam | Fox Searchlight Pictures | $33,269 | -14.4% | +12.2% | 177 | $187 | $1,465,481 | 36 | - | false |
| 22 | 22 | Funny People | Universal Pictures | $32,995 | -11.6% | -69.3% | 413 | $79 | $51,431,880 | 34 | - | false |
| 23 | 24 | A Perfect Getaway | Universal Pictures | $32,555 | -7.6% | -69.1% | 544 | $59 | $15,102,115 | 27 | - | false |
| 24 | 23 | The Hurt Locker | Summit Entertainment | $32,131 | -11.9% | -37.9% | 306 | $105 | $11,694,665 | 69 | - | false |
| 25 | 26 | Under the Sea 3D | Warner Bros. | $32,034 | +0.6% | -45.3% | 108 | $296 | $16,790,855 | 202 | - | false |
| 26 | 25 | My Sister's Keeper | Warner Bros. | $28,078 | -12% | +53% | 326 | $86 | $48,495,332 | 69 | - | false |
| 27 | 27 | Aliens in the Attic | Twentieth Century Fox | $27,190 | -9.2% | -50.9% | 574 | $47 | $23,074,515 | 34 | - | false |
| 28 | 28 | The September Issue | Roadside Attractions | $26,691 | -3% | - | 6 | $4,448 | $301,862 | 6 | - | false |
| 29 | 29 | Star Trek | Paramount Pictures | $22,560 | +1.4% | -22.1% | 218 | $103 | $256,739,608 | 118 | - | false |
| 30 | 31 | Night at the Museum: Battle of the Smithsonian | Twentieth Century Fox | $19,569 | +0.9% | -41.3% | 232 | $84 | $176,521,110 | 104 | - | false |
| 31 | 30 | Public Enemies | Universal Pictures | $18,465 | -12.4% | -30.3% | 264 | $69 | $97,087,425 | 64 | - | false |
| 32 | 32 | Paper Heart | Overture Films | $13,264 | -6.1% | -31% | 96 | $138 | $978,864 | 27 | - | false |
| 33 | 33 | My One and Only | Freestyle Releasing | $8,782 | +6.2% | +17.7% | 10 | $878 | $191,175 | 13 | - | false |
| 34 | 35 | The Cove | Roadside Attractions | $7,350 | +12.6% | -20.1% | 25 | $294 | $639,588 | 34 | - | false |
| 35 | 34 | Bandslam | Summit Entertainment | $6,151 | -24.7% | -93.3% | 207 | $29 | $4,957,088 | 20 | - | false |
| 36 | 36 | Kaminey | UTV Motion Pictures | $5,316 | +2.5% | -58.7% | 63 | $84 | $1,219,428 | 20 | - | false |
| 37 | 37 | Terminator Salvation | Warner Bros. | $3,095 | -9% | -55.9% | 81 | $38 | $125,296,477 | 105 | - | false |
| 38 | 39 | I Love You, Beth Cooper | Twentieth Century Fox | $2,719 | -1.7% | -58.1% | 77 | $35 | $14,714,852 | 55 | - | false |
| 39 | 47 | American Casino | Argot Pictures | $2,690 | +2,104.9% | +1,937.9% | 2 | $1,345 | $10,067 | 20 | - | false |
| 40 | 38 | The Collector | Freestyle Releasing | $2,479 | -15.3% | -64.7% | 37 | $67 | $7,552,919 | 34 | - | false |
| 41 | 40 | Spread | Anchor Bay Films | $2,024 | -4.4% | -2.6% | 45 | $44 | $245,122 | 20 | - | false |
| 42 | 42 | X-Men Origins: Wolverine | Twentieth Century Fox | $1,626 | +31.4% | -20.7% | 26 | $62 | $179,867,762 | 125 | - | false |
| 43 | 43 | The Open Road | Anchor Bay Films | $727 | -23.8% | - | 14 | $51 | $15,672 | 6 | - | false |
| 44 | 45 | Mystery Team | Roadside Attractions | $624 | +67.3% | - | 1 | $624 | $9,206 | 6 | - | false |
| 45 | 44 | Shrink | Roadside Attractions | $567 | -1.4% | +94.2% | 8 | $70 | $181,603 | 41 | - | false |
| 46 | 46 | The Stoning of Soraya M. | Roadside Attractions | $222 | +41.4% | -73.9% | 4 | $55 | $622,120 | 69 | - | false |
| 47 | 48 | Z | Rialto Pictures | $118 | +6.3% | - | 1 | $118 | $80,737 | 174 | - | false |
| 48 | 49 | Goodbye Solo | Roadside Attractions | $46 | -56.2% | - | 5 | $9 | $867,038 | 160 | - | false |
