| TD | YD | Release
| Distributor
| Daily | %± YD | %± LW | Theaters | Avg | To Date | Days | New This Day
| Estimated
|
|---|
| 1 | 1 | District 9 | TriStar Pictures | $3,866,075 | -16% | - | 3,049 | $1,267 | $50,986,939 | 6 | - | false |
| 2 | 2 | G.I. Joe: The Rise of Cobra | Paramount Pictures | $2,185,769 | -15.6% | -54.6% | 4,007 | $545 | $105,962,679 | 13 | - | false |
| 3 | 3 | The Time Traveler's Wife | Warner Bros. | $2,055,357 | -17.1% | - | 2,988 | $687 | $25,495,671 | 6 | - | false |
| 4 | 4 | Julie & Julia | Sony Pictures Releasing | $1,733,388 | -8.8% | -36.5% | 2,354 | $736 | $48,604,980 | 13 | - | false |
| 5 | 5 | G-Force | Walt Disney Studios Motion Pictures | $958,557 | -14.9% | -33.7% | 3,065 | $312 | $102,143,778 | 27 | - | false |
| 6 | 7 | Harry Potter and the Half-Blood Prince | Warner Bros. | $696,426 | -8.3% | -39.6% | 2,771 | $251 | $286,072,062 | 36 | - | false |
| 7 | 6 | The Goods: Live Hard, Sell Hard | Paramount Vantage | $665,900 | -17.6% | - | 1,838 | $362 | $7,953,169 | 6 | - | false |
| 8 | 8 | The Ugly Truth | Sony Pictures Releasing | $629,637 | -12.2% | -37.1% | 2,733 | $230 | $79,436,358 | 27 | - | false |
| 9 | 9 | Ponyo | Walt Disney Studios Motion Pictures | $521,182 | -8% | - | 927 | $562 | $5,233,143 | 6 | - | false |
| 10 | 10 | 500 Days of Summer | Fox Searchlight Pictures | $459,151 | -11.1% | -27% | 1,048 | $438 | $19,374,497 | 34 | - | false |
| 11 | 11 | Funny People | Universal Pictures | $413,440 | -13.5% | -59.6% | 2,584 | $160 | $49,254,205 | 20 | - | false |
| 12 | 12 | A Perfect Getaway | Universal Pictures | $367,030 | -15% | -42.4% | 2,159 | $170 | $12,758,160 | 13 | - | false |
| 13 | 13 | Bandslam | Summit Entertainment | $312,201 | -19.3% | - | 2,121 | $147 | $3,276,853 | 6 | - | false |
| 14 | 14 | The Hangover | Warner Bros. | $252,414 | -2.1% | -44.9% | 1,185 | $213 | $266,553,834 | 76 | - | false |
| 15 | 15 | Aliens in the Attic | Twentieth Century Fox | $229,300 | -5.3% | -66.9% | 1,535 | $149 | $21,273,486 | 20 | - | false |
| 16 | 17 | Orphan | Warner Bros. | $187,343 | -10.1% | -60.5% | 1,261 | $148 | $38,960,778 | 27 | - | false |
| 17 | 16 | Ice Age: Dawn of the Dinosaurs | Twentieth Century Fox | $180,326 | -23.9% | -55.2% | 858 | $210 | $191,455,470 | 50 | - | false |
| 18 | 18 | Transformers: Revenge of the Fallen | DreamWorks | $177,654 | -5.3% | -48.4% | 1,007 | $176 | $397,300,205 | 57 | - | false |
| 19 | 19 | The Proposal | Walt Disney Studios Motion Pictures | $164,136 | -6.2% | -59.6% | 1,084 | $151 | $158,200,057 | 62 | - | false |
| 20 | 20 | The Hurt Locker | Summit Entertainment | $93,190 | -6.5% | -48.9% | 478 | $194 | $10,650,589 | 55 | - | false |
| 21 | 21 | Under the Sea 3D | Warner Bros. | $80,655 | +6.5% | -10% | 40 | $2,016 | $15,828,114 | 188 | - | false |
| 22 | 22 | Night at the Museum: Battle of the Smithsonian | Twentieth Century Fox | $61,851 | -8.7% | -21% | 278 | $222 | $175,723,823 | 90 | - | false |
| 23 | 23 | Star Trek | Paramount Pictures | $45,549 | -13.1% | -34.5% | 303 | $150 | $256,083,762 | 104 | - | false |
| 24 | 24 | Public Enemies | Universal Pictures | $42,065 | -11.8% | -64.3% | 367 | $114 | $96,478,505 | 50 | - | false |
| 25 | 26 | Adam | Fox Searchlight Pictures | $32,889 | -9.8% | +73.3% | 66 | $498 | $613,617 | 22 | - | false |
| 26 | 27 | The Collector | Freestyle Releasing | $30,056 | -7.8% | -82.2% | 262 | $114 | $7,374,179 | 20 | - | false |
| 27 | 25 | Kaminey | UTV Motion Pictures | $29,933 | -28.2% | - | 85 | $352 | $827,408 | 6 | - | false |
| 28 | 28 | Paper Heart | Overture Films | $25,879 | -11.6% | -15.3% | 68 | $380 | $602,458 | 13 | - | false |
| 29 | 29 | My Sister's Keeper | Warner Bros. | $23,580 | -15% | -52.9% | 202 | $116 | $47,930,474 | 55 | - | false |
| 30 | 30 | Spread | Anchor Bay Films | $19,706 | -7.5% | - | 103 | $191 | $183,968 | 6 | - | false |
| 31 | 32 | Terminator Salvation | Warner Bros. | $15,063 | -7% | -47.8% | 203 | $74 | $125,139,292 | 91 | - | false |
| 32 | 31 | Brüno | Universal Pictures | $14,910 | -12.5% | -48.4% | 142 | $105 | $60,041,040 | 41 | - | false |
| 33 | 33 | The Cove | Roadside Attractions | $14,615 | -6.5% | -40.9% | 53 | $275 | $469,075 | 20 | - | false |
| 34 | 34 | I Love You, Beth Cooper | Twentieth Century Fox | $10,850 | -15% | -6.9% | 140 | $77 | $14,590,694 | 41 | - | false |
| 35 | 35 | Monsters vs. Aliens | DreamWorks | $8,950 | -13.4% | -59.8% | 116 | $77 | $198,282,222 | 146 | - | false |
| 36 | 36 | Imagine That | Paramount Pictures | $8,888 | -5.3% | -38.8% | 107 | $83 | $16,114,912 | 69 | - | false |
| 37 | 38 | Thirst | Focus Features | $8,817 | -4.8% | +2.4% | 15 | $587 | $253,937 | 20 | - | false |
| 38 | 37 | Life Partner | Studio 18 | $6,868 | -25.9% | - | 26 | $264 | $71,030 | 6 | - | false |
| 39 | 39 | Away We Go | Focus Features | $4,815 | +5.7% | -56.1% | 54 | $89 | $9,444,355 | 76 | - | false |
| 40 | 41 | Chéri | Miramax | $4,612 | +83% | -25.7% | 30 | $153 | $2,694,235 | 55 | - | false |
| 41 | 40 | X-Men Origins: Wolverine | Twentieth Century Fox | $3,626 | -11.1% | -49.1% | 64 | $56 | $179,812,947 | 111 | - | false |
| 42 | - | Made in U.S.A | Rialto Pictures | $1,525 | - | - | 1 | $1,525 | $95,209 | 223 | - | false |
| 43 | 43 | Shrink | Roadside Attractions | $759 | -7.7% | -71.5% | 3 | $253 | $167,825 | 27 | - | false |
| 44 | 45 | Grace | Anchor Bay Films | $550 | +15.5% | - | 2 | $275 | $7,708 | 6 | - | false |
| 45 | 44 | The Stoning of Soraya M. | Roadside Attractions | $539 | -2.7% | -62.3% | 8 | $67 | $611,944 | 55 | - | false |
| 46 | 47 | Goodbye Solo | Roadside Attractions | $344 | +23.3% | -68.2% | 4 | $86 | $864,798 | 146 | - | false |
| 47 | 46 | American Casino | Argot Pictures | $279 | -3.5% | - | 1 | $279 | $2,245 | 6 | - | false |
| 48 | - | Alien Trespass | Roadside Attractions | $80 | - | - | 1 | $80 | $102,733 | 139 | - | false |
