| TD | YD | Release
| Distributor
| Daily | %± YD | %± LW | Theaters | Avg | To Date | Days | New This Day
| Estimated
|
|---|
| 1 | 1 | District 9 | TriStar Pictures | $4,604,348 | -10.8% | - | 3,049 | $1,510 | $47,120,864 | 5 | - | false |
| 2 | 2 | G.I. Joe: The Rise of Cobra | Paramount Pictures | $2,588,366 | -0.9% | -56.6% | 4,007 | $645 | $103,776,910 | 12 | - | false |
| 3 | 3 | The Time Traveler's Wife | Warner Bros. | $2,478,724 | +6% | - | 2,988 | $829 | $23,440,314 | 5 | - | false |
| 4 | 4 | Julie & Julia | Sony Pictures Releasing | $1,901,060 | +16.6% | -38.2% | 2,354 | $807 | $46,871,592 | 12 | - | false |
| 5 | 5 | G-Force | Walt Disney Studios Motion Pictures | $1,126,182 | +12.3% | -31.7% | 3,065 | $367 | $101,185,221 | 26 | - | false |
| 6 | 6 | The Goods: Live Hard, Sell Hard | Paramount Vantage | $807,872 | -3.5% | - | 1,838 | $439 | $7,287,269 | 5 | - | false |
| 7 | 7 | Harry Potter and the Half-Blood Prince | Warner Bros. | $759,364 | +3% | -42.3% | 2,771 | $274 | $285,375,636 | 35 | - | false |
| 8 | 8 | The Ugly Truth | Sony Pictures Releasing | $717,177 | +12.2% | -38.7% | 2,733 | $262 | $78,806,721 | 26 | - | false |
| 9 | 9 | Ponyo | Walt Disney Studios Motion Pictures | $566,788 | +1.3% | - | 927 | $611 | $4,711,961 | 5 | - | false |
| 10 | 10 | 500 Days of Summer | Fox Searchlight Pictures | $516,447 | +3% | -23.6% | 1,048 | $492 | $18,915,346 | 33 | - | false |
| 11 | 11 | Funny People | Universal Pictures | $477,945 | +5.7% | -60.3% | 2,584 | $184 | $48,840,765 | 19 | - | false |
| 12 | 12 | A Perfect Getaway | Universal Pictures | $431,800 | +8.2% | -45.1% | 2,159 | $200 | $12,391,130 | 12 | - | false |
| 13 | 13 | Bandslam | Summit Entertainment | $386,770 | +11.6% | - | 2,121 | $182 | $2,964,652 | 5 | - | false |
| 14 | 14 | The Hangover | Warner Bros. | $257,750 | +1.8% | -43.8% | 1,185 | $217 | $266,301,420 | 75 | - | false |
| 15 | 15 | Aliens in the Attic | Twentieth Century Fox | $242,112 | +3.8% | -68.5% | 1,535 | $157 | $21,044,186 | 19 | - | false |
| 16 | 17 | Ice Age: Dawn of the Dinosaurs | Twentieth Century Fox | $236,892 | +29.6% | -50% | 858 | $276 | $191,275,144 | 49 | - | false |
| 17 | 16 | Orphan | Warner Bros. | $208,280 | -4.6% | -61.3% | 1,261 | $165 | $38,773,435 | 26 | - | false |
| 18 | 18 | Transformers: Revenge of the Fallen | DreamWorks | $187,634 | +6.4% | -50.7% | 1,007 | $186 | $397,122,551 | 56 | - | false |
| 19 | 19 | The Proposal | Walt Disney Studios Motion Pictures | $175,000 | +4.2% | -59.3% | 1,084 | $161 | $158,035,921 | 61 | - | false |
| 20 | 20 | The Hurt Locker | Summit Entertainment | $99,716 | +8.6% | -48.3% | 478 | $208 | $10,557,399 | 54 | - | false |
| 21 | 21 | Under the Sea 3D | Warner Bros. | $75,705 | +22.3% | -14.5% | 40 | $1,892 | $15,747,459 | 187 | - | false |
| 22 | 22 | Night at the Museum: Battle of the Smithsonian | Twentieth Century Fox | $67,772 | +22.2% | -22.6% | 278 | $243 | $175,661,972 | 89 | - | false |
| 23 | 23 | Star Trek | Paramount Pictures | $52,427 | +5.8% | -30.6% | 303 | $173 | $256,038,213 | 103 | - | false |
| 24 | 24 | Public Enemies | Universal Pictures | $47,710 | +8.3% | -63.6% | 367 | $130 | $96,436,440 | 49 | - | false |
| 25 | 28 | Kaminey | UTV Motion Pictures | $41,680 | +43.9% | - | 85 | $490 | $797,475 | 5 | - | false |
| 26 | 26 | Adam | Fox Searchlight Pictures | $36,470 | +18.4% | +115.6% | 66 | $552 | $580,728 | 21 | - | false |
| 27 | 25 | The Collector | Freestyle Releasing | $32,601 | +3.7% | -82.8% | 262 | $124 | $7,344,123 | 19 | - | false |
| 28 | 27 | Paper Heart | Overture Films | $29,269 | -2.1% | -13% | 68 | $430 | $576,579 | 12 | - | false |
| 29 | 29 | My Sister's Keeper | Warner Bros. | $27,741 | +7.3% | -50.9% | 202 | $137 | $47,906,894 | 54 | - | false |
| 30 | 30 | Spread | Anchor Bay Films | $21,306 | +6.5% | - | 103 | $206 | $164,262 | 5 | - | false |
| 31 | 31 | Brüno | Universal Pictures | $17,040 | +4.3% | -51% | 142 | $120 | $60,026,130 | 40 | - | false |
| 32 | 32 | Terminator Salvation | Warner Bros. | $16,197 | +10.4% | -46.9% | 203 | $79 | $125,124,229 | 90 | - | false |
| 33 | 33 | The Cove | Roadside Attractions | $15,625 | +12.1% | -33.6% | 53 | $294 | $454,460 | 19 | - | false |
| 34 | 34 | I Love You, Beth Cooper | Twentieth Century Fox | $12,765 | +13% | -4.7% | 140 | $91 | $14,579,844 | 40 | - | false |
| 35 | 37 | Monsters vs. Aliens | DreamWorks | $10,335 | +37.8% | -35.1% | 116 | $89 | $198,273,272 | 145 | - | false |
| 36 | 35 | Imagine That | Paramount Pictures | $9,390 | +17% | -36.9% | 107 | $87 | $16,106,024 | 68 | - | false |
| 37 | 38 | Life Partner | Studio 18 | $9,273 | +85.8% | - | 26 | $356 | $64,162 | 5 | - | false |
| 38 | 36 | Thirst | Focus Features | $9,262 | +16% | -3.1% | 15 | $617 | $245,120 | 19 | - | false |
| 39 | 39 | Away We Go | Focus Features | $4,555 | +14% | -59.6% | 54 | $84 | $9,439,540 | 75 | - | false |
| 40 | 40 | X-Men Origins: Wolverine | Twentieth Century Fox | $4,078 | +3.4% | -48.6% | 64 | $63 | $179,809,321 | 110 | - | false |
| 41 | 41 | Chéri | Miramax | $2,520 | -17.4% | -62% | 30 | $84 | $2,689,623 | 54 | - | false |
| 42 | 42 | War Eagle, Arkansas | Hannover House | $1,513 | -23.6% | +2,508.6% | 2 | $756 | $123,670 | 68 | - | false |
| 43 | 43 | Shrink | Roadside Attractions | $822 | -20.2% | -74.8% | 3 | $274 | $167,066 | 26 | - | false |
| 44 | 45 | The Stoning of Soraya M. | Roadside Attractions | $554 | -8.9% | -66.8% | 8 | $69 | $611,405 | 54 | - | false |
| 45 | 46 | Grace | Anchor Bay Films | $476 | -6.3% | - | 2 | $238 | $7,158 | 5 | - | false |
| 46 | 48 | American Casino | Argot Pictures | $289 | +3.2% | - | 1 | $289 | $1,966 | 5 | - | false |
| 47 | 47 | Goodbye Solo | Roadside Attractions | $279 | -26.8% | -51.1% | 4 | $69 | $864,454 | 145 | - | false |
