| TD | YD | Release
| Distributor
| Daily | %± YD | %± LW | Theaters | Avg | To Date | Days | New This Day
| Estimated
|
|---|
| 1 | 1 | G-Force | Walt Disney Studios Motion Pictures | $4,003,224 | -14.7% | - | 3,697 | $1,082 | $49,403,423 | 7 | - | false |
| 2 | 2 | Harry Potter and the Half-Blood Prince | Warner Bros. | $3,842,107 | -16.2% | -44% | 4,455 | $862 | $237,762,860 | 16 | - | false |
| 3 | 3 | The Ugly Truth | Sony Pictures Releasing | $3,027,219 | -11.3% | - | 2,882 | $1,050 | $41,481,408 | 7 | - | false |
| 4 | 4 | Orphan | Warner Bros. | $1,510,126 | -8.1% | - | 2,750 | $549 | $19,541,393 | 7 | - | false |
| 5 | 5 | Ice Age: Dawn of the Dinosaurs | Twentieth Century Fox | $1,201,480 | -11.4% | -56.5% | 3,300 | $364 | $176,542,789 | 30 | - | false |
| 6 | 6 | The Proposal | Walt Disney Studios Motion Pictures | $1,012,057 | -4.7% | -29.7% | 2,779 | $364 | $144,033,677 | 42 | - | false |
| 7 | 7 | Transformers: Revenge of the Fallen | DreamWorks | $959,667 | -7.1% | -45.7% | 3,237 | $296 | $383,500,991 | 37 | - | false |
| 8 | 8 | The Hangover | Warner Bros. | $888,214 | -6.6% | -28% | 2,285 | $388 | $250,696,417 | 56 | - | false |
| 9 | 9 | Public Enemies | Universal Pictures | $560,885 | -9.3% | -45.5% | 2,291 | $244 | $90,672,355 | 30 | - | false |
| 10 | 10 | Brüno | Universal Pictures | $331,625 | -16.7% | -63.6% | 1,895 | $175 | $58,211,990 | 21 | - | false |
| 11 | 11 | Up | Walt Disney Studios Motion Pictures | $299,671 | -11.8% | -53.1% | 1,070 | $280 | $284,878,665 | 63 | - | false |
| 12 | 12 | 500 Days of Summer | Fox Searchlight Pictures | $259,631 | -6.5% | +90.1% | 85 | $3,054 | $4,070,615 | 14 | - | false |
| 13 | 13 | My Sister's Keeper | Warner Bros. | $251,377 | -4.2% | -53.5% | 1,258 | $199 | $46,091,506 | 35 | - | false |
| 14 | 14 | The Hurt Locker | Summit Entertainment | $198,368 | -8.2% | +73.4% | 238 | $833 | $4,846,165 | 35 | - | false |
| 15 | 15 | I Love You, Beth Cooper | Twentieth Century Fox | $129,384 | -3% | -75.9% | 730 | $177 | $13,908,227 | 21 | - | false |
| 16 | 16 | Night at the Museum: Battle of the Smithsonian | Twentieth Century Fox | $111,422 | -5.4% | -24.3% | 396 | $281 | $173,454,677 | 70 | - | false |
| 17 | 17 | Under the Sea 3D | Warner Bros. | $99,200 | -10.5% | -8.3% | 40 | $2,480 | $14,023,161 | 168 | - | false |
| 18 | 18 | Star Trek | Paramount Pictures | $78,962 | -7.2% | -34.4% | 307 | $257 | $254,334,469 | 84 | - | false |
| 19 | 19 | Away We Go | Focus Features | $44,056 | -10.1% | -42.3% | 206 | $213 | $9,042,089 | 56 | - | false |
| 20 | 21 | Imagine That | Paramount Pictures | $35,200 | -3.5% | +134.8% | 221 | $159 | $15,674,345 | 49 | - | false |
| 21 | 20 | Land of the Lost | Universal Pictures | $34,020 | -9.7% | -20.4% | 243 | $140 | $49,109,665 | 56 | - | false |
| 22 | 22 | Monsters vs. Aliens | DreamWorks | $32,108 | -4.9% | -25.2% | 210 | $152 | $197,895,942 | 126 | - | false |
| 23 | 23 | Chéri | Miramax | $27,179 | -3.4% | -31.5% | 188 | $144 | $2,452,642 | 35 | - | false |
| 24 | 25 | Ghosts of Girlfriends Past | Warner Bros. | $22,604 | +1% | -25.1% | 145 | $155 | $55,116,122 | 91 | - | false |
| 25 | 24 | X-Men Origins: Wolverine | Twentieth Century Fox | $21,926 | -6.8% | -34.1% | 181 | $121 | $179,556,048 | 91 | - | false |
| 26 | 26 | Terminator Salvation | Warner Bros. | $19,414 | -2.4% | -46.7% | 148 | $131 | $124,182,894 | 71 | - | false |
| 27 | 28 | Drag Me to Hell | Universal Pictures | $15,695 | +4.9% | -32.1% | 150 | $104 | $41,965,725 | 63 | - | false |
| 28 | 27 | Adam | Fox Searchlight Pictures | $13,132 | -14.6% | - | 4 | $3,283 | $28,511 | 2 | - | false |
| 29 | 29 | 17 Again | Warner Bros. | $9,548 | +6% | -56.2% | 76 | $125 | $64,122,946 | 105 | - | false |
| 30 | 30 | The Stoning of Soraya M. | Roadside Attractions | $7,500 | +7% | -26.4% | 30 | $250 | $546,554 | 35 | - | false |
| 31 | 31 | The Brothers Bloom | Summit Entertainment | $5,770 | -14.7% | -7.4% | 49 | $117 | $3,503,013 | 77 | - | false |
| 32 | 32 | My Life in Ruins | Fox Searchlight Pictures | $5,275 | -13.6% | -39.3% | 46 | $114 | $8,558,780 | 56 | - | false |
| 33 | 33 | Shrink | Roadside Attractions | $1,869 | +7.5% | - | 2 | $934 | $23,856 | 7 | - | false |
| 34 | 34 | You, the Living | Palisades Tartan | $1,728 | +7.1% | - | 1 | $1,728 | $3,342 | 2 | - | false |
| 35 | - | Made in U.S.A | Rialto Pictures | $1,108 | - | - | 1 | $1,108 | $89,351 | 203 | - | false |
| 36 | 35 | Goodbye Solo | Roadside Attractions | $524 | -8.1% | -1.9% | 12 | $43 | $844,645 | 126 | - | false |
| 37 | 36 | Battle for Terra | Lionsgate | $30 | -79.7% | -91.8% | 1 | $30 | $1,645,271 | 91 | - | false |
| 38 | 37 | The Golden Boys | Roadside Attractions | $12 | +100% | - | 1 | $12 | $43,486 | 105 | - | false |
