| TD | YD | Release
| Distributor
| Daily | %± YD | %± LW | Theaters | Avg | To Date | Days | New This Day
| Estimated
|
|---|
| 1 | 1 | The Dark Knight | Warner Bros. | $24,493,313 | -43.8% | - | 4,366 | $5,610 | $182,904,796 | 4 | - | false |
| 2 | 2 | Mamma Mia! | Universal Pictures | $4,093,125 | -49.1% | - | 2,976 | $1,375 | $31,844,365 | 4 | - | false |
| 3 | 3 | Hancock | Sony Pictures Releasing | $1,684,785 | -58.2% | -55.8% | 3,776 | $446 | $193,228,764 | 20 | - | false |
| 4 | 4 | Journey to the Center of the Earth | Warner Bros. | $1,624,423 | -58.1% | -40.4% | 2,830 | $574 | $45,129,135 | 11 | - | false |
| 5 | 5 | WALL·E | Walt Disney Studios Motion Pictures | $1,425,526 | -54.7% | -44.7% | 3,310 | $430 | $184,158,235 | 25 | - | false |
| 6 | 6 | Hellboy II: The Golden Army | Universal Pictures | $1,172,380 | -62.6% | -68.5% | 3,212 | $365 | $57,699,265 | 11 | - | false |
| 7 | 7 | Space Chimps | Twentieth Century Fox | $987,040 | -51.4% | - | 2,511 | $393 | $8,168,414 | 4 | - | false |
| 8 | 8 | Wanted | Universal Pictures | $656,910 | -57.5% | -58.8% | 2,433 | $270 | $123,979,545 | 25 | - | false |
| 9 | 9 | Get Smart | Warner Bros. | $558,395 | -48.9% | -45.4% | 2,135 | $261 | $120,167,090 | 32 | - | false |
| 10 | 10 | Kung Fu Panda | DreamWorks | $282,367 | -54% | -58.8% | 1,505 | $187 | $206,898,748 | 46 | - | false |
| 11 | 11 | Meet Dave | Twentieth Century Fox | $242,285 | -50.7% | -64% | 3,011 | $80 | $9,640,694 | 11 | - | false |
| 12 | 12 | Kit Kittredge: An American Girl | Picturehouse | $198,947 | -36% | -56.5% | 769 | $258 | $13,968,251 | 32 | - | false |
| 13 | 14 | Sex and the City | Warner Bros. | $115,711 | -45.4% | -52.5% | 515 | $224 | $149,986,166 | 53 | - | false |
| 14 | 13 | Indiana Jones and the Kingdom of the Crystal Skull | Paramount Pictures | $114,879 | -57.6% | -57.9% | 757 | $151 | $312,684,340 | 61 | - | false |
| 15 | 15 | The Incredible Hulk | Universal Pictures | $88,560 | -50.9% | -73.2% | 656 | $135 | $131,855,725 | 39 | - | false |
| 16 | 16 | Iron Man | Paramount Pictures | $55,221 | -54.1% | -56.2% | 375 | $147 | $314,432,189 | 81 | - | false |
| 17 | 18 | Mongol: The Rise of Genghis Khan | Picturehouse | $31,231 | -61.8% | -51.8% | 195 | $160 | $4,898,721 | 46 | - | false |
| 18 | 20 | What Happens in Vegas | Twentieth Century Fox | $23,645 | -50% | -33.2% | 252 | $93 | $79,540,051 | 74 | - | false |
| 19 | 21 | The Happening | Twentieth Century Fox | $20,715 | -55.3% | -63.7% | 242 | $85 | $63,757,240 | 39 | - | false |
| 20 | 19 | The Visitor | Overture Films | $17,949 | -64% | -42.6% | 133 | $134 | $8,835,681 | 102 | - | false |
| 21 | 23 | Speed Racer | Warner Bros. | $16,643 | -46.8% | -28.5% | 200 | $83 | $43,757,018 | 74 | - | false |
| 22 | 22 | The Strangers | Rogue Pictures | $15,350 | -51.5% | -41% | 192 | $79 | $52,549,645 | 53 | - | false |
| 23 | 24 | The Love Guru | Paramount Pictures | $12,898 | -46.6% | -84.1% | 183 | $70 | $31,818,425 | 32 | - | false |
| 24 | 25 | Baby Mama | Universal Pictures | $12,005 | -46.6% | -31.5% | 150 | $80 | $60,281,345 | 88 | - | false |
| 25 | 26 | Nim's Island | Twentieth Century Fox | $11,171 | -49.3% | -41.8% | 127 | $87 | $47,836,671 | 109 | - | false |
| 26 | 27 | Horton Hears a Who! | Twentieth Century Fox | $9,433 | -42.1% | -12.3% | 122 | $77 | $154,310,261 | 130 | - | false |
| 27 | 30 | Deep Sea | Warner Bros. | $9,079 | -4.1% | +40.6% | 8 | $1,134 | $35,767,260 | 872 | - | false |
| 28 | 28 | The Fall | Roadside Attractions | $5,186 | -53.9% | -48.1% | 38 | $136 | $2,104,149 | 74 | - | false |
| 29 | 31 | Young@Heart | Fox Searchlight Pictures | $4,113 | -55.4% | -23.2% | 47 | $87 | $3,833,299 | 104 | - | false |
| 30 | 29 | Before the Rains | Roadside Attractions | $3,603 | -62.3% | -45.8% | 22 | $163 | $864,387 | 74 | - | false |
| 31 | 33 | Berlin | Third Rail Releasing | $1,647 | -42% | - | 2 | $823 | $9,927 | 4 | - | false |
| 32 | 32 | Son of Rambow | Paramount Vantage | $1,183 | -59.2% | -26.5% | 26 | $45 | $1,740,845 | 81 | - | false |
| 33 | 35 | Reprise | Miramax | $931 | -56% | -37.7% | 15 | $62 | $549,742 | 67 | - | false |
| 34 | 34 | The Stone Angel | Vivendi Entertainment | $752 | -69.8% | -73.4% | 5 | $150 | $433,768 | 11 | - | false |
| 35 | 36 | Superhero Movie | - | $509 | -67.3% | -39% | 12 | $42 | $25,872,343 | 116 | - | false |
| 36 | 37 | Garden Party | Roadside Attractions | $504 | -51.1% | -68.7% | 4 | $126 | $20,357 | 11 | - | false |
| 37 | 38 | Last Year at Marienbad | Rialto Pictures | $300 | -53% | - | 2 | $150 | $139,900 | 186 | - | false |
| 38 | 40 | The Foot Fist Way | Paramount Vantage | $213 | -16.8% | -72.8% | 5 | $42 | $230,114 | 53 | - | false |
| 39 | 39 | Chicago 10 | Roadside Attractions | $122 | -54% | - | 1 | $122 | $176,667 | 144 | - | false |
