Domestic Box Office For Jul 21, 2006
| TD | YD | Release | Distributor | Daily | %± YD | %± LW | Theaters | Avg | To Date | Days |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | Pirates of the Caribbean: Dead Man's Chest | Walt Disney Studios Motion Pictures | $9,992,181 | +54.5% | -46.1% | 4,133 | $2,417 | $296,676,213 | 15 |
| 2 | - | Monster House | Sony Pictures Releasing | $7,362,974 | - | - | 3,553 | $2,072 | $7,362,974 | 1 |
| 3 | - | Lady in the Water | Warner Bros. | $6,851,808 | - | - | 3,235 | $2,118 | $6,851,808 | 1 |
| 4 | - | Clerks II | - | $4,020,770 | - | - | 2,150 | $1,870 | $4,020,770 | 1 |
| 5 | 2 | You, Me and Dupree | Universal Pictures | $3,983,990 | +58.1% | -47% | 3,137 | $1,270 | $36,515,480 | 8 |
| 6 | 3 | Little Man | Revolution Studios | $3,320,847 | +82.3% | -56% | 2,537 | $1,308 | $32,931,969 | 8 |
| 7 | - | My Super Ex-Girlfriend | Twentieth Century Fox | $2,731,482 | - | - | 2,702 | $1,010 | $2,731,482 | 1 |
| 8 | 5 | The Devil Wears Prada | Twentieth Century Fox | $2,175,102 | +32.9% | -31.8% | 2,248 | $967 | $92,321,571 | 22 |
| 9 | 4 | Superman Returns | Warner Bros. | $1,961,440 | +18.3% | -41.8% | 2,826 | $694 | $172,928,938 | 24 |
| 10 | 6 | Cars | Walt Disney Studios Motion Pictures | $1,360,866 | +15.4% | -40.5% | 2,410 | $564 | $225,899,304 | 43 |
| 11 | 7 | Click | Revolution Studios | $1,187,937 | +10.8% | -44.9% | 2,312 | $513 | $125,376,517 | 29 |
| 12 | 10 | An Inconvenient Truth | Paramount Classics | $236,844 | +15.4% | -16.5% | 440 | $538 | $18,026,745 | 59 |
| 13 | 12 | A Scanner Darkly | Warner Independent Pictures (WIP) | $191,656 | +22.4% | -50.4% | 219 | $875 | $2,752,425 | 15 |
| 14 | 8 | The Lake House | Warner Bros. | $176,329 | -34.3% | -64.6% | 603 | $292 | $50,213,092 | 36 |
| 15 | 9 | Nacho Libre | Paramount Pictures | $143,413 | -40.3% | -70.1% | 505 | $283 | $78,331,232 | 36 |
| 16 | 14 | The Break-Up | Universal Pictures | $140,070 | +4.1% | -48% | 406 | $345 | $116,754,450 | 50 |
| 17 | 15 | The Da Vinci Code | Sony Pictures Releasing | $120,516 | -7.3% | -47.3% | 322 | $374 | $215,524,434 | 64 |
| 18 | - | RV | Sony Pictures Releasing | $112,812 | - | +3.5% | 316 | $357 | $69,711,457 | 85 |
| 19 | 11 | The Fast and the Furious: Tokyo Drift | Universal Pictures | $111,375 | -30.3% | -69% | 405 | $275 | $60,599,215 | 36 |
| 20 | 17 | Deep Sea | Warner Bros. | $107,652 | +5.7% | +18.4% | 38 | $2,832 | $14,518,580 | 141 |
| 21 | 18 | A Prairie Home Companion | Picturehouse | $100,445 | +12.7% | -40.7% | 297 | $338 | $18,420,406 | 43 |
| 22 | 16 | Over the Hedge | DreamWorks | $91,428 | -25.1% | -39.2% | 329 | $277 | $151,437,372 | 64 |
| 23 | 13 | Garfield: A Tail of Two Kitties | Twentieth Century Fox | $86,389 | -43% | -51% | 372 | $232 | $26,911,632 | 36 |
| 24 | 20 | X-Men: The Last Stand | Twentieth Century Fox | $85,613 | +14.4% | -41.8% | 332 | $257 | $232,716,758 | 57 |
| 25 | 24 | Poseidon | Warner Bros. | $39,107 | +24.7% | -50% | 231 | $169 | $60,323,770 | 71 |
| 26 | 22 | Ice Age: The Meltdown | Twentieth Century Fox | $36,960 | +5.8% | -22.6% | 182 | $203 | $194,796,994 | 113 |
| 27 | 26 | Leonard Cohen: I'm Your Man | Lionsgate | $23,278 | +47.5% | -17.1% | 40 | $581 | $403,515 | 31 |
| 28 | 25 | The Omen | Twentieth Century Fox | $19,651 | +15.1% | -41.6% | 158 | $124 | $54,352,309 | 46 |
| 29 | 27 | Peaceful Warrior | Lionsgate | $13,880 | +4.6% | -47.3% | 37 | $375 | $805,519 | 50 |
| 30 | 29 | Thank You for Smoking | Fox Searchlight Pictures | $11,478 | +12.5% | -23.4% | 39 | $294 | $24,592,403 | 127 |
| 31 | 30 | Water 2006 Re-release | Fox Searchlight Pictures | $9,907 | +18.1% | -26.4% | 42 | $235 | $3,005,348 | 85 |
| 32 | 31 | Scary Movie 4 | - | $8,317 | +18.3% | -48.1% | 69 | $120 | $90,650,088 | 99 |