| Rank
| Title
| Lifetime Gross
| Year
|
|---|
| 401 | Gran Torino | $148,095,302 | 2008 |
| 402 | Lethal Weapon 2 | $147,253,986 | 1989 |
| 403 | War for the Planet of the Apes | $146,880,162 | 2017 |
| 404 | X-Men: First Class | $146,408,305 | 2011 |
| 405 | Paul Blart: Mall Cop | $146,336,178 | 2009 |
| 406 | True Lies | $146,282,411 | 1994 |
| 407 | Lilo & Stitch | $145,794,338 | 2002 |
| 408 | The Santa Clause | $145,539,357 | 1994 |
| 409 | The Meg | $145,522,784 | 2018 |
| 410 | American Pie 2 | $145,103,595 | 2001 |
| 411 | Taken | $145,000,989 | 2009 |
| 412 | One Hundred and One Dalmatians | $144,880,014 | 1961 |
| 413 | The Great Gatsby | $144,857,996 | 2013 |
| 414 | I, Robot | $144,801,023 | 2004 |
| 415 | The Fast and the Furious | $144,745,925 | 2001 |
| 416 | Lethal Weapon 3 | $144,731,527 | 1992 |
| 417 | Pokémon: Detective Pikachu | $144,174,568 | 2019 |
| 418 | Mamma Mia! | $144,169,664 | 2008 |
| 419 | Doctor Dolittle | $144,156,605 | 1998 |
| 420 | Rio | $143,619,809 | 2011 |
| 421 | Kung Fu Panda 3 | $143,528,619 | 2016 |
| 422 | Juno | $143,495,265 | 2007 |
| 423 | Marley & Me | $143,153,751 | 2008 |
| 424 | The Smurfs | $142,614,158 | 2011 |
| 425 | Once Upon a Time... In Hollywood | $142,502,728 | 2019 |
| 426 | xXx | $142,109,382 | 2002 |
| 427 | The Jungle Book | $141,843,612 | 1967 |
| 428 | The Chronicles of Narnia: Prince Caspian | $141,621,490 | 2008 |
| 429 | National Lampoon's Animal House | $141,600,000 | 1978 |
| 430 | Pocahontas | $141,579,773 | 1995 |
| 431 | A Few Good Men | $141,340,178 | 1992 |
| 432 | Slumdog Millionaire | $141,319,928 | 2008 |
| 433 | Rush Hour | $141,186,864 | 1998 |
| 434 | The Blair Witch Project | $140,539,099 | 1999 |
| 435 | Shazam! | $140,480,049 | 2019 |
| 436 | Deep Impact | $140,464,664 | 1998 |
| 437 | Ocean's Eight | $140,295,726 | 2018 |
| 438 | Rush Hour 3 | $140,125,968 | 2007 |
| 439 | Look Who's Talking | $140,088,813 | 1989 |
| 440 | Stuart Little | $140,035,367 | 1999 |
| 441 | Taken 2 | $139,854,287 | 2012 |
| 442 | Sister Act | $139,605,150 | 1992 |
| 443 | The Matrix Revolutions | $139,313,948 | 2003 |
| 444 | The Santa Clause 2 | $139,236,327 | 2002 |
| 445 | The King's Speech | $138,797,449 | 2010 |
| 446 | Cheaper by the Dozen | $138,614,544 | 2003 |
| 447 | Bad Boys II | $138,608,444 | 2003 |
| 448 | Platoon | $138,530,565 | 1986 |
| 449 | 21 Jump Street | $138,447,667 | 2012 |
| 450 | Good Will Hunting | $138,433,435 | 1997 |
| 451 | Split | $138,291,365 | 2017 |
| 452 | A Christmas Carol | $137,855,863 | 2009 |
| 453 | Dinosaur | $137,748,063 | 2000 |
| 454 | Ready Player One | $137,715,350 | 2018 |
| 455 | The Conjuring | $137,446,368 | 2013 |
| 456 | Click | $137,355,633 | 2006 |
| 457 | The Green Mile | $136,801,374 | 1999 |
| 458 | Ransom | $136,492,681 | 1996 |
| 459 | The Godfather | $136,381,073 | 1972 |
| 460 | Godzilla | $136,314,294 | 1998 |
| 461 | 101 Dalmatians | $136,189,294 | 1996 |
| 462 | Argo | $136,025,503 | 2012 |
| 463 | Anger Management | $135,645,823 | 2003 |
| 464 | Chicken Little | $135,386,665 | 2005 |
| 465 | Teenage Mutant Ninja Turtles | $135,384,756 | 1990 |
| 466 | Close Encounters of the Third Kind | $135,189,114 | 1977 |
| 467 | Patch Adams | $135,026,902 | 1998 |
| 468 | Ride Along | $134,938,200 | 2014 |
| 469 | The Incredible Hulk | $134,806,913 | 2008 |
| 470 | Live Free or Die Hard | $134,529,403 | 2007 |
| 471 | Wanted | $134,508,551 | 2008 |
| 472 | Identity Thief | $134,506,920 | 2013 |
| 473 | Superman | $134,478,449 | 1978 |
| 474 | The Rock | $134,069,511 | 1996 |
| 475 | Mission: Impossible III | $134,029,801 | 2006 |
| 476 | Grown Ups 2 | $133,668,525 | 2013 |
| 477 | Troy | $133,378,256 | 2004 |
| 478 | Angels & Demons | $133,375,846 | 2009 |
| 479 | Alvin and the Chipmunks: Chipwrecked | $133,110,742 | 2011 |
| 480 | Bringing Down the House | $132,716,677 | 2003 |
| 481 | The Wolverine | $132,556,852 | 2013 |
| 482 | Wonder | $132,422,809 | 2017 |
| 483 | The Departed | $132,399,394 | 2006 |
| 484 | Hulk | $132,177,234 | 2003 |
| 485 | Silver Linings Playbook | $132,092,958 | 2012 |
| 486 | Minority Report | $132,072,926 | 2002 |
| 487 | Fantastic 4: Rise of the Silver Surfer | $131,921,738 | 2007 |
| 488 | The Last Airbender | $131,772,187 | 2010 |
| 489 | Rio 2 | $131,538,435 | 2014 |
| 490 | Lara Croft: Tomb Raider | $131,168,070 | 2001 |
| 491 | The Silence of the Lambs | $130,742,922 | 1991 |
| 492 | Honey, I Shrunk the Kids | $130,724,172 | 1989 |
| 493 | The Flintstones | $130,531,208 | 1994 |
| 494 | Lethal Weapon 4 | $130,444,603 | 1998 |
| 495 | Get Smart | $130,319,208 | 2008 |
| 496 | The Divergent Series: Insurgent | $130,179,072 | 2015 |
| 497 | The Peanuts Movie | $130,178,411 | 2015 |
| 498 | Transformers: The Last Knight | $130,168,683 | 2017 |
| 499 | American Gangster | $130,164,645 | 2007 |
| 500 | American Beauty | $130,096,601 | 1999 |
| 501 | An Officer and a Gentleman | $129,795,554 | 1982 |
| 502 | Ghostbusters: Afterlife | $129,360,575 | 2021 |
| 503 | The Ring | $129,128,133 | 2002 |
| 504 | The Nutty Professor | $128,814,019 | 1996 |
| 505 | Borat: Cultural Learnings of America for Make Benefit Glorious Nation of Kazakhstan | $128,505,958 | 2006 |
| 506 | Ghostbusters | $128,350,574 | 2016 |
| 507 | Kingsman: The Secret Service | $128,261,724 | 2015 |
| 508 | Robots | $128,200,012 | 2005 |
| 509 | Coming to America | $128,152,301 | 1988 |
| 510 | Crouching Tiger, Hidden Dragon | $128,078,872 | 2000 |
| 511 | Shutter Island | $128,012,934 | 2010 |
| 512 | Into the Woods | $128,002,372 | 2014 |
| 513 | Rocky IV | $127,873,716 | 1985 |
| 514 | Enchanted | $127,807,262 | 2007 |
| 515 | The Curious Case of Benjamin Button | $127,509,326 | 2008 |
| 516 | Central Intelligence | $127,440,871 | 2016 |
| 517 | Anchorman 2: The Legend Continues | $127,352,707 | 2013 |
| 518 | Sweet Home Alabama | $127,223,418 | 2002 |
| 519 | Bumblebee | $127,195,589 | 2018 |
| 520 | Dumb and Dumber | $127,190,327 | 1994 |
| 521 | 2 Fast 2 Furious | $127,154,901 | 2003 |
| 522 | My Best Friend's Wedding | $127,120,029 | 1997 |
| 523 | Super 8 | $127,004,179 | 2011 |
| 524 | The World Is Not Enough | $126,943,684 | 1999 |
| 525 | Sleepless in Seattle | $126,808,165 | 1993 |
| 526 | Smokey and the Bandit | $126,737,428 | 1977 |
| 527 | Lucy | $126,663,600 | 2014 |
| 528 | The Legend of Tarzan | $126,643,061 | 2016 |
| 529 | Bee Movie | $126,631,277 | 2007 |
| 530 | Prometheus | $126,477,084 | 2012 |
| 531 | Safe House | $126,373,434 | 2012 |
| 532 | Mr. Deeds | $126,293,452 | 2002 |
| 533 | The Truman Show | $125,618,201 | 1998 |
| 534 | Erin Brockovich | $125,595,205 | 2000 |
| 535 | Ocean's Twelve | $125,544,280 | 2004 |
| 536 | Terminator Salvation | $125,322,469 | 2009 |
| 537 | Charlie's Angels | $125,305,545 | 2000 |
| 538 | Tomorrow Never Dies | $125,304,276 | 1997 |
| 539 | Minions: The Rise of Gru | $125,190,000 | 2022 |
| 540 | Lone Survivor | $125,095,601 | 2013 |
| 541 | Sully | $125,070,033 | 2016 |
| 542 | Rocky III | $125,049,125 | 1982 |
| 543 | The Vow | $125,014,030 | 2012 |
| 544 | Life of Pi | $124,987,023 | 2012 |
| 545 | The Fault in Our Stars | $124,872,350 | 2014 |
| 546 | Cloudy with a Chance of Meatballs | $124,870,275 | 2009 |
| 547 | The Devil Wears Prada | $124,740,460 | 2006 |
| 548 | Something's Gotta Give | $124,728,738 | 2003 |
| 549 | Traffic | $124,115,725 | 2000 |
| 550 | The Birdcage | $124,060,553 | 1996 |
| 551 | City Slickers | $124,033,791 | 1991 |
| 552 | Good Morning, Vietnam | $123,922,370 | 1987 |
| 553 | Rango | $123,477,607 | 2011 |
| 554 | Nutty Professor II: The Klumps | $123,309,890 | 2000 |
| 555 | The Good Dinosaur | $123,087,120 | 2015 |
| 556 | G.I. Joe: Retaliation | $122,523,060 | 2013 |
| 557 | Clear and Present Danger | $122,187,717 | 1994 |
| 558 | The Bodyguard | $122,046,449 | 1992 |
| 559 | The Hunt for Red October | $122,012,643 | 1990 |
| 560 | Wayne's World | $121,697,323 | 1992 |
| 561 | The Bourne Identity | $121,661,683 | 2002 |
| 562 | Free Guy | $121,626,598 | 2021 |
| 563 | Superbad | $121,463,226 | 2007 |
| 564 | Speed | $121,248,145 | 1994 |
| 565 | 50 First Dates | $120,908,074 | 2004 |
| 566 | Mamma Mia! Here We Go Again | $120,634,935 | 2018 |
| 567 | Mulan | $120,620,254 | 1998 |
| 568 | Inglourious Basterds | $120,540,719 | 2009 |
| 569 | Seabiscuit | $120,277,854 | 2003 |
| 570 | Van Helsing | $120,177,084 | 2004 |
| 571 | Four Christmases | $120,146,040 | 2008 |
| 572 | I Now Pronounce You Chuck & Larry | $120,059,556 | 2007 |
| 573 | The Mask | $119,938,730 | 1994 |
| 574 | Cloudy with a Chance of Meatballs 2 | $119,793,567 | 2013 |
| 575 | Hook | $119,654,823 | 1991 |
| 576 | Blazing Saddles | $119,616,663 | 1974 |
| 577 | Walk the Line | $119,519,402 | 2005 |
| 578 | G-Force | $119,436,770 | 2009 |
| 579 | Total Recall | $119,412,921 | 1990 |
| 580 | On Golden Pond | $119,285,432 | 1981 |
| 581 | The Other Guys | $119,219,978 | 2010 |
| 582 | Fahrenheit 9/11 | $119,194,771 | 2004 |
| 583 | Back to the Future Part II | $119,000,002 | 1989 |
| 584 | Hairspray | $118,946,291 | 2007 |
| 585 | The Sum of All Fears | $118,907,036 | 2002 |
| 586 | The Break-Up | $118,703,275 | 2006 |
| 587 | A Series of Unfortunate Events | $118,634,549 | 2004 |
| 588 | Blades of Glory | $118,594,548 | 2007 |
| 589 | Salt | $118,311,368 | 2010 |
| 590 | Basic Instinct | $117,727,224 | 1992 |
| 591 | Now You See Me | $117,723,989 | 2013 |
| 592 | Ford v Ferrari | $117,624,357 | 2019 |
| 593 | Big Momma's House | $117,559,438 | 2000 |
| 594 | Die Hard 2 | $117,540,947 | 1990 |
| 595 | Horrible Bosses | $117,538,559 | 2011 |
| 596 | The Nun | $117,481,222 | 2018 |
| 597 | Rocky | $117,235,147 | 1976 |
| 598 | Jackass 3D | $117,229,692 | 2010 |
| 599 | Ocean's Thirteen | $117,154,724 | 2007 |
| 600 | Jungle Cruise | $116,987,516 | 2021 |
