| Rank
| Title
| Lifetime Gross
| Year
|
|---|
| 401 | X-Men | $157,299,718 | 2000 |
| 402 | The Mummy | $157,095,368 | 1999 |
| 403 | Scary Movie | $157,019,771 | 2000 |
| 404 | Fatal Attraction | $156,645,693 | 1987 |
| 405 | Who Framed Roger Rabbit | $156,452,370 | 1988 |
| 406 | Creed III | $156,248,615 | 2023 |
| 407 | The Sting | $156,000,000 | 1973 |
| 408 | What Lies Beneath | $155,464,351 | 2000 |
| 409 | X-Men: Apocalypse | $155,442,489 | 2016 |
| 410 | Snow White and the Huntsman | $155,332,381 | 2012 |
| 411 | San Andreas | $155,190,832 | 2015 |
| 412 | Fast & Furious | $155,064,265 | 2009 |
| 413 | Over the Hedge | $155,019,340 | 2006 |
| 414 | Fantastic Four | $154,696,080 | 2005 |
| 415 | Horton Hears a Who! | $154,529,439 | 2008 |
| 416 | Elemental | $154,426,697 | 2023 |
| 417 | Mad Max: Fury Road | $154,280,290 | 2015 |
| 418 | Trolls | $154,174,089 | 2016 |
| 419 | Jerry Maguire | $153,952,592 | 1996 |
| 420 | Beverly Hills Cop II | $153,665,036 | 1987 |
| 421 | Gremlins | $153,642,180 | 1984 |
| 422 | Scooby-Doo | $153,322,074 | 2002 |
| 423 | Cars 3 | $152,901,115 | 2017 |
| 424 | Sex and the City | $152,647,258 | 2008 |
| 425 | Runaway Bride | $152,257,509 | 1999 |
| 426 | La La Land | $151,101,803 | 2016 |
| 427 | Elvis | $151,040,048 | 2022 |
| 428 | Divergent | $150,947,895 | 2014 |
| 429 | Rambo: First Blood Part II | $150,415,432 | 1985 |
| 430 | We're the Millers | $150,394,119 | 2013 |
| 431 | Terminator 3: Rise of the Machines | $150,371,112 | 2003 |
| 432 | Daddy's Home | $150,357,137 | 2015 |
| 433 | G.I. Joe: The Rise of Cobra | $150,201,498 | 2009 |
| 434 | Neighbors | $150,157,400 | 2014 |
| 435 | American Hustle | $150,117,807 | 2013 |
| 436 | Puss in Boots | $149,260,504 | 2011 |
| 437 | Les Misérables | $149,260,140 | 2012 |
| 438 | Sonic the Hedgehog | $148,974,665 | 2020 |
| 439 | Knocked Up | $148,768,917 | 2007 |
| 440 | Uncharted | $148,648,820 | 2022 |
| 441 | It Ends with Us | $148,518,266 | 2024 |
| 442 | As Good as It Gets | $148,478,011 | 1997 |
| 443 | Little Fockers | $148,438,600 | 2010 |
| 444 | Hotel Transylvania | $148,426,305 | 2012 |
| 445 | Megamind | $148,415,853 | 2010 |
| 446 | Talladega Nights: The Ballad of Ricky Bobby | $148,213,377 | 2006 |
| 447 | Gran Torino | $148,095,302 | 2008 |
| 448 | Lethal Weapon 2 | $147,253,986 | 1989 |
| 449 | War for the Planet of the Apes | $146,880,162 | 2017 |
| 450 | X-Men: First Class | $146,408,305 | 2011 |
| 451 | Paul Blart: Mall Cop | $146,336,178 | 2009 |
| 452 | True Lies | $146,282,411 | 1994 |
| 453 | Fast X | $146,126,015 | 2023 |
| 454 | Lilo & Stitch | $145,794,338 | 2002 |
| 455 | The Santa Clause | $145,539,357 | 1994 |
| 456 | The Meg | $145,522,784 | 2018 |
| 457 | American Pie 2 | $145,103,595 | 2001 |
| 458 | Taken | $145,000,989 | 2009 |
| 459 | One Hundred and One Dalmatians | $144,880,014 | 1961 |
| 460 | The Great Gatsby | $144,857,996 | 2013 |
| 461 | I, Robot | $144,801,023 | 2004 |
| 462 | The Fast and the Furious | $144,745,925 | 2001 |
| 463 | Lethal Weapon 3 | $144,731,527 | 1992 |
| 464 | Mamma Mia! | $144,330,569 | 2008 |
| 465 | Pokémon: Detective Pikachu | $144,174,568 | 2019 |
| 466 | Doctor Dolittle | $144,156,605 | 1998 |
| 467 | The Wild Robot | $143,901,945 | 2024 |
| 468 | Rio | $143,619,809 | 2011 |
| 469 | Kung Fu Panda 3 | $143,528,619 | 2016 |
| 470 | Juno | $143,495,265 | 2007 |
| 471 | Marley & Me | $143,153,751 | 2008 |
| 472 | The Smurfs | $142,614,158 | 2011 |
| 473 | Once Upon a Time... in Hollywood | $142,502,728 | 2019 |
| 474 | xXx | $142,109,382 | 2002 |
| 475 | The Jungle Book | $141,843,612 | 1967 |
| 476 | The Chronicles of Narnia: Prince Caspian | $141,621,490 | 2008 |
| 477 | National Lampoon's Animal House | $141,600,000 | 1978 |
| 478 | Pocahontas | $141,579,773 | 1995 |
| 479 | A Few Good Men | $141,340,178 | 1992 |
| 480 | Slumdog Millionaire | $141,319,928 | 2008 |
| 481 | Rush Hour | $141,186,864 | 1998 |
| 482 | The Blair Witch Project | $140,539,099 | 1999 |
| 483 | Shazam! | $140,480,049 | 2019 |
| 484 | Deep Impact | $140,464,664 | 1998 |
| 485 | Ocean's Eight | $140,295,726 | 2018 |
| 486 | Rush Hour 3 | $140,125,968 | 2007 |
| 487 | Look Who's Talking | $140,088,813 | 1989 |
| 488 | Stuart Little | $140,035,367 | 1999 |
| 489 | Taken 2 | $139,854,287 | 2012 |
| 490 | Venom: The Last Dance | $139,755,882 | 2024 |
| 491 | Sister Act | $139,605,150 | 1992 |
| 492 | The Matrix Revolutions | $139,313,948 | 2003 |
| 493 | The Santa Clause 2 | $139,236,327 | 2002 |
| 494 | A Quiet Place: Day One | $139,051,884 | 2024 |
| 495 | The King's Speech | $138,797,449 | 2010 |
| 496 | Cheaper by the Dozen | $138,614,544 | 2003 |
| 497 | Bad Boys II | $138,608,444 | 2003 |
| 498 | Platoon | $138,530,565 | 1986 |
| 499 | 21 Jump Street | $138,447,667 | 2012 |
| 500 | Good Will Hunting | $138,433,435 | 1997 |
| 501 | Split | $138,291,365 | 2017 |
| 502 | A Christmas Carol | $137,855,863 | 2009 |
| 503 | Dinosaur | $137,748,063 | 2000 |
| 504 | Ready Player One | $137,715,350 | 2018 |
| 505 | The Conjuring | $137,446,368 | 2013 |
| 506 | Click | $137,355,633 | 2006 |
| 507 | Five Nights at Freddy's | $137,275,620 | 2023 |
| 508 | The Green Mile | $136,801,374 | 1999 |
| 509 | Ransom | $136,492,681 | 1996 |
| 510 | The Godfather | $136,381,073 | 1972 |
| 511 | Godzilla | $136,314,294 | 1998 |
| 512 | 101 Dalmatians | $136,189,294 | 1996 |
| 513 | Argo | $136,025,503 | 2012 |
| 514 | Anger Management | $135,645,823 | 2003 |
| 515 | Chicken Little | $135,386,665 | 2005 |
| 516 | Teenage Mutant Ninja Turtles | $135,384,756 | 1990 |
| 517 | Close Encounters of the Third Kind | $135,189,114 | 1977 |
| 518 | Patch Adams | $135,026,902 | 1998 |
| 519 | Ride Along | $134,938,200 | 2014 |
| 520 | The Incredible Hulk | $134,806,913 | 2008 |
| 521 | Live Free or Die Hard | $134,529,403 | 2007 |
| 522 | Wanted | $134,508,551 | 2008 |
| 523 | Identity Thief | $134,506,920 | 2013 |
| 524 | Superman | $134,478,449 | 1978 |
| 525 | The Rock | $134,069,511 | 1996 |
| 526 | Mission: Impossible III | $134,029,801 | 2006 |
| 527 | Grown Ups 2 | $133,668,525 | 2013 |
| 528 | Troy | $133,378,256 | 2004 |
| 529 | Angels & Demons | $133,375,846 | 2009 |
| 530 | Alvin and the Chipmunks: Chipwrecked | $133,110,742 | 2011 |
| 531 | Bringing Down the House | $132,716,677 | 2003 |
| 532 | The Wolverine | $132,556,852 | 2013 |
| 533 | Wonder | $132,422,809 | 2017 |
| 534 | The Departed | $132,399,394 | 2006 |
| 535 | Hulk | $132,177,234 | 2003 |
| 536 | Silver Linings Playbook | $132,092,958 | 2012 |
| 537 | Minority Report | $132,072,926 | 2002 |
| 538 | Fantastic Four: Rise of the Silver Surfer | $131,921,738 | 2007 |
| 539 | Final Destination: Bloodlines | $131,919,192 | 2025 |
| 540 | The Last Airbender | $131,772,187 | 2010 |
| 541 | Rio 2 | $131,538,435 | 2014 |
| 542 | Lara Croft: Tomb Raider | $131,168,070 | 2001 |
| 543 | The Silence of the Lambs | $130,742,922 | 1991 |
| 544 | Honey, I Shrunk the Kids | $130,724,172 | 1989 |
| 545 | The Flintstones | $130,531,208 | 1994 |
| 546 | Lethal Weapon 4 | $130,444,603 | 1998 |
| 547 | Get Smart | $130,319,208 | 2008 |
| 548 | Insurgent | $130,179,072 | 2015 |
| 549 | The Peanuts Movie | $130,178,411 | 2015 |
| 550 | Transformers: The Last Knight | $130,168,683 | 2017 |
| 551 | American Gangster | $130,164,645 | 2007 |
| 552 | American Beauty | $130,096,601 | 1999 |
| 553 | An Officer and a Gentleman | $129,795,554 | 1982 |
| 554 | Ghostbusters: Afterlife | $129,471,867 | 2021 |
| 555 | The Ring | $129,128,133 | 2002 |
| 556 | The Nutty Professor | $128,814,019 | 1996 |
| 557 | Crouching Tiger, Hidden Dragon | $128,530,421 | 2000 |
| 558 | Borat | $128,505,958 | 2006 |
| 559 | Ghostbusters | $128,350,574 | 2016 |
| 560 | Kingsman: The Secret Service | $128,261,724 | 2015 |
| 561 | Robots | $128,200,012 | 2005 |
| 562 | Coming to America | $128,152,301 | 1988 |
| 563 | Shutter Island | $128,012,934 | 2010 |
| 564 | Into the Woods | $128,002,372 | 2014 |
| 565 | Rocky IV | $127,873,716 | 1985 |
| 566 | Enchanted | $127,807,262 | 2007 |
| 567 | Migration | $127,630,880 | 2023 |
| 568 | The Curious Case of Benjamin Button | $127,509,326 | 2008 |
| 569 | Central Intelligence | $127,440,871 | 2016 |
| 570 | Anchorman 2: The Legend Continues | $127,352,707 | 2013 |
| 571 | Sweet Home Alabama | $127,223,418 | 2002 |
| 572 | Bumblebee | $127,195,589 | 2018 |
| 573 | Dumb and Dumber | $127,190,327 | 1994 |
| 574 | 2 Fast 2 Furious | $127,154,901 | 2003 |
| 575 | My Best Friend's Wedding | $127,120,029 | 1997 |
| 576 | Super 8 | $127,004,179 | 2011 |
| 577 | The World Is Not Enough | $126,943,684 | 1999 |
| 578 | Sleepless in Seattle | $126,808,165 | 1993 |
| 579 | Smokey and the Bandit | $126,737,428 | 1977 |
| 580 | Lucy | $126,663,600 | 2014 |
| 581 | The Legend of Tarzan | $126,643,061 | 2016 |
| 582 | Bee Movie | $126,631,277 | 2007 |
| 583 | Prometheus | $126,477,084 | 2012 |
| 584 | Safe House | $126,373,434 | 2012 |
| 585 | Mr. Deeds | $126,293,452 | 2002 |
| 586 | The Truman Show | $125,618,201 | 1998 |
| 587 | Erin Brockovich | $125,595,205 | 2000 |
| 588 | Ocean's Twelve | $125,544,280 | 2004 |
| 589 | Terminator Salvation | $125,322,469 | 2009 |
| 590 | Charlie's Angels | $125,305,545 | 2000 |
| 591 | Tomorrow Never Dies | $125,304,276 | 1997 |
| 592 | Lone Survivor | $125,095,601 | 2013 |
| 593 | Sully | $125,070,033 | 2016 |
| 594 | Rocky III | $125,049,125 | 1982 |
| 595 | The Vow | $125,014,030 | 2012 |
| 596 | Life of Pi | $124,987,023 | 2012 |
| 597 | The Fault in Our Stars | $124,872,350 | 2014 |
| 598 | Cloudy with a Chance of Meatballs | $124,870,275 | 2009 |
| 599 | The Devil Wears Prada | $124,740,460 | 2006 |
| 600 | Something's Gotta Give | $124,728,738 | 2003 |
