| Rank | Release | Total Gross | Top Rank | Overall Rank | Year | Distributor | 
|---|
| 1 | Spider-Man | $24,876,515 | 9 | 60 | 2002 | Sony Pictures Releasing | 
| 2 | Spider-Man 2 | $16,186,273 | 14 | 157 | 2004 | - | 
| 3 | Shark Tale | $11,116,168 | 10 | 360 | 2004 | United International Pictures | 
| 4 | The Secret in Their Eyes | $8,220,014 | 35 | 541 | 2009 | Alta Films | 
| 5 | Sorority Row | $7,787,224 | 11 | 577 | 2009 | Aurum Films | 
| 6 | Godzilla vs. Kong | $7,600,000 | 8 | 598 | 2021 | Warner Bros. | 
| 7 | Collateral | $7,269,986 | 13 | 639 | 2004 | United International Pictures | 
| 8 | The Amazing Spider-Man 2 2024 Re-release | $7,132,326 | 17 | 162 | - | Sony Pictures Releasing | 
| 9 | The Artist | $6,686,116 | 7 | 725 | 2011 | Alta Films | 
| 10 | Broken Embraces | $5,928,682 | 36 | 820 | 2009 | Warner Bros. | 
| 11 | The Hobbit: The Battle of the Five Armies 2020 Re-release | $5,710,065 | 18 | 122 | - | Warner Bros. | 
| 12 | Ferpect Crime | $5,453,374 | 9 | 901 | 2004 | - | 
| 13 | Exorcist: The Beginning | $5,284,764 | 8 | 922 | 2004 | Warner Bros. | 
| 14 | Welcome to the Sticks | $4,921,136 | 6 | 990 | 2009 | Wanda Visión S.A. | 
| 15 | El ratón Pérez | $4,892,243 | 49 | 995 | 2006 | Filmax | 
| 16 | Little Miss Sunshine | $4,688,542 | 9 | 1,029 | 2006 | 20th Century Fox International | 
| 17 | Melinda and Melinda | $4,525,827 | 7 | 1,062 | 2004 | 20th Century Fox International | 
| 18 | The Forgotten | $4,449,886 | 14 | 1,078 | 2004 | - | 
| 19 | Two | $4,353,761 | 25 | 1,098 | 2021 | Filmax | 
| 20 | 47 Ronin | $4,294,943 | 6 | 1,116 | 2013 | United International Pictures | 
| 21 | Delicious | $4,236,946 | 9 | 1,132 | 2021 | A Contracorriente Films | 
| 22 | The Secret Life of Words | $4,092,793 | 8 | 1,178 | 2005 | Warner Bros. | 
| 23 | Arthur Christmas | $4,089,776 | 6 | 1,179 | 2011 | Sony Pictures Releasing | 
| 24 | Death at a Funeral | $3,949,527 | 7 | 1,214 | 2007 | DeAPlaneta | 
| 25 | The Tale of Despereaux | $3,948,152 | 7 | 1,215 | 2008 | Universal Pictures International (UPI) | 
| 26 | Underdogs | $3,941,325 | 9 | 1,218 | 2013 | Universal Pictures International (UPI) | 
| 27 | The Hurt Locker | $3,930,210 | 7 | 1,220 | 2010 | DeAPlaneta | 
| 28 | The Counterfeiters | $3,871,085 | 8 | 1,236 | 2008 | Wanda Visión S.A. | 
| 29 | Case 39 | $3,837,870 | 7 | 1,244 | 2009 | Paramount Pictures International | 
| 30 | Smile 2 | $3,803,613 | 8 | 1,252 | 2024 | Paramount Pictures International | 
| 31 | Black Bread | $3,770,657 | 10 | 1,258 | 2010 | - | 
| 32 | Habana Blues | $3,642,445 | 7 | 1,292 | 2005 | Warner Bros. | 
| 33 | Son of Bigfoot | $3,596,214 | 6 | 1,311 | 2018 | Flins & Piniculas | 
| 34 | Cassandra's Dream | $3,416,432 | 7 | 1,379 | 2007 | On Pictures | 
| 35 | White Chicks | $3,379,297 | 15 | 1,391 | 2004 | - | 
| 36 | Unit 7 | $3,273,873 | 6 | 1,425 | 2012 | Warner Bros. | 
| 37 | Till the wedding do us part | $3,246,816 | 30 | 1,433 | - | A Contracorriente Films | 
| 38 | Walking with Dinosaurs 3D | $3,246,358 | 7 | 1,434 | 2013 | - | 
| 39 | Step Up 2 the Streets | $3,223,112 | 7 | 1,444 | 2008 | Walt Disney Pictures | 
| 40 | Tom & Jerry | $3,206,678 | 7 | 1,453 | 2021 | Warner Bros. | 
| 41 | Hitman | $3,180,289 | 6 | 1,459 | 2007 | 20th Century Fox International | 
| 42 | Wonder Park | $3,168,623 | 6 | 1,461 | 2019 | Paramount Pictures International | 
| 43 | The Imitation Game | $3,101,966 | 6 | 1,484 | 2015 | TriPictures | 
| 44 | Drive | $3,096,335 | 7 | 1,485 | 2011 | Walt Disney Pictures | 
| 45 | In the Valley of Elah | $3,046,512 | 6 | 1,504 | 2008 | Aurum Films | 
| 46 | Transsiberian | $2,997,144 | 6 | 1,518 | 2008 | Filmax | 
| 47 | Map of the Sounds of Tokyo | $2,990,991 | 8 | 1,523 | 2009 | Alta Films | 
| 48 | The Spirit | $2,978,413 | 6 | 1,527 | 2008 | Sony Pictures Releasing | 
| 49 | The 40-Year-Old Virgin | $2,969,873 | 6 | 1,530 | 2005 | United International Pictures | 
| 50 | The Method | $2,917,250 | 6 | 1,546 | 2005 | On Pictures | 
| 51 | Earth | $2,899,993 | 10 | 1,556 | 2007 | Wanda Visión S.A. | 
| 52 | About Time | $2,894,564 | 6 | 1,557 | 2013 | Universal Pictures International (UPI) | 
| 53 | The Queen | $2,887,973 | 7 | 1,558 | 2006 | Vértigo Films | 
| 54 | Because I Said So | $2,886,017 | 6 | 1,560 | 2007 | Aurum Films | 
| 55 | The Next Three Days | $2,826,141 | 6 | 1,580 | 2011 | TriPictures | 
| 56 | Bambi II | $2,810,462 | 7 | 1,586 | 2006 | Buena Vista International | 
| 57 | Amigos... | $2,806,622 | 6 | 1,589 | 2011 | TriPictures | 
| 58 | Precious | $2,794,276 | 8 | 1,597 | 2010 | Filmax | 
| 59 | The Conspiracy | $2,784,297 | 7 | 1,603 | 2008 | Sony Pictures Releasing | 
| 60 | Sky Captain and the World of Tomorrow | $2,777,444 | 6 | 1,610 | 2004 | DeAPlaneta | 
| 61 | Meet Dave | $2,745,239 | 6 | 1,626 | 2008 | 20th Century Fox International | 
| 62 | Saw | $2,738,218 | 7 | 1,630 | 2005 | DeAPlaneta | 
| 63 | Anatomy of a Fall | $2,729,780 | 7 | 1,636 | 2023 | Elastica | 
| 64 | A Turtle's Tale: Sammy's Adventures | $2,726,421 | 6 | 1,638 | 2011 | - | 
| 65 | Moonlight | $2,722,635 | 6 | 1,642 | 2017 | Diamond Films | 
| 66 | Cats & Dogs: The Revenge of Kitty Galore | $2,710,677 | 6 | 1,647 | 2010 | Warner Bros. | 
| 67 | The Photographer of Mauthausen | $2,701,645 | 6 | 1,650 | 2018 | Filmax | 
| 68 | Carmina y amén. | $2,690,532 | 6 | 1,653 | 2014 | - | 
| 69 | Paranormal Activity | $2,679,752 | 6 | 1,656 | 2009 | Warner Bros. | 
| 70 | Paranormal Xperience 3D | $2,674,168 | 6 | 1,658 | 2011 | Sony Pictures Releasing | 
| 71 | Living Is Easy with Eyes Closed | $2,622,237 | 6 | 1,670 | 2013 | Universal Pictures International (UPI) | 
| 72 | Arthur and the Revenge of Maltazard | $2,616,888 | 7 | 1,674 | 2010 | DeAPlaneta | 
| 73 | Julie & Julia | $2,597,806 | 6 | 1,684 | 2009 | Sony Pictures Releasing | 
| 74 | Happy Feet Two | $2,587,355 | 6 | 1,690 | 2011 | Warner Bros. | 
| 75 | Twin Murders: The Silence of the White City | $2,575,843 | 8 | 1,695 | 2019 | DeAPlaneta | 
| 76 | Lone Survivor | $2,569,756 | 6 | 1,697 | 2014 | - | 
| 77 | Bella | $2,507,983 | 8 | 1,718 | 2008 | E.D. Distribution | 
| 78 | A Gun in Each Hand | $2,507,288 | 6 | 1,719 | 2012 | Filmax | 
| 79 | Prime | $2,453,321 | 6 | 1,745 | 2006 | Aurum Films | 
| 80 | Margin Call | $2,449,037 | 7 | 1,746 | 2011 | Wanda Visión S.A. | 
| 81 | Noah's Ark | $2,448,956 | 8 | 1,747 | 2007 | Sony Pictures Releasing | 
| 82 | Coco Before Chanel | $2,448,911 | 6 | 1,748 | 2009 | Warner Bros. | 
| 83 | Miss Congeniality 2: Armed & Fabulous | $2,428,299 | 6 | 1,757 | 2005 | Warner Bros. | 
| 84 | Obaba | $2,419,554 | 8 | 1,759 | 2005 | Alta Films | 
| 85 | The Last King of Scotland | $2,418,979 | 7 | 1,760 | 2007 | 20th Century Fox International | 
| 86 | There Will Be Blood | $2,415,805 | 10 | 1,762 | 2008 | Walt Disney Pictures | 
| 87 | The Lincoln Lawyer | $2,385,567 | 6 | 1,774 | 2011 | Aurum Films | 
| 88 | The Best Offer | $2,371,645 | 7 | 1,781 | 2013 | Filmax | 
| 89 | Hotel for Dogs | $2,369,928 | 6 | 1,783 | 2009 | Paramount Pictures International | 
| 90 | 16 Blocks | $2,362,372 | 6 | 1,786 | 2006 | Filmax | 
| 91 | The Pact | $2,352,858 | 22 | 1,791 | 2021 | Adso Films | 
| 92 | The Jacket | $2,334,033 | 6 | 1,800 | 2006 | TriPictures | 
| 93 | Good Boys | $2,331,148 | 7 | 1,802 | 2019 | Universal Pictures International (UPI) | 
| 94 | The Possession of Hannah Grace | $2,330,548 | 6 | 1,803 | 2018 | Sony Pictures Releasing | 
| 95 | Smurfs | $2,329,522 | 6 | 1,804 | 2025 | Paramount Pictures International | 
| 96 | Barnyard | $2,302,952 | 6 | 1,816 | 2006 | United International Pictures | 
| 97 | Suso's Tower | $2,302,645 | 6 | 1,818 | 2007 | Warner Bros. | 
| 98 | Manchester by the Sea | $2,286,051 | 6 | 1,829 | 2017 | Universal Pictures International (UPI) | 
| 99 | Jigsaw | $2,269,079 | 7 | 1,836 | 2017 | DeAPlaneta | 
| 100 | The Lion King 2011 3D Release | $2,264,185 | 8 | 41 | 2011 | Walt Disney Pictures | 
| 101 | Lust, Caution | $2,247,011 | 7 | 1,850 | 2007 | Universal Pictures International (UPI) | 
| 102 | The Reef | $2,242,910 | 9 | 1,851 | 2007 | Manga Entertainment | 
| 103 | Bumblebee | $2,242,363 | 6 | 1,852 | 2018 | Paramount Pictures International | 
| 104 | The Great Beauty | $2,227,594 | 12 | 1,862 | 2013 | Wanda Visión S.A. | 
| 105 | The White Ribbon | $2,226,344 | 10 | 1,863 | 2010 | Golem Distribución | 
| 106 | The Code | $2,225,004 | 6 | 1,865 | 2009 | DeAPlaneta | 
| 107 | Winchester | $2,217,835 | 6 | 1,868 | 2018 | Vértice 360 | 
| 108 | Two Brothers | $2,208,775 | 8 | 1,871 | 2004 | TriPictures | 
| 109 | Goya's Ghosts | $2,198,929 | 6 | 1,875 | 2006 | Warner Bros. | 
| 110 | Scream 4 | $2,197,129 | 7 | 1,876 | 2011 | United International Pictures | 
| 111 | Isi/Disi: Alto voltaje | $2,194,607 | 6 | 1,878 | 2006 | Azteca Films | 
| 112 | The Machinist | $2,187,884 | 7 | 1,884 | 2004 | Filmax | 
| 113 | The Ant Bully | $2,181,265 | 6 | 1,885 | 2006 | Warner Bros. | 
| 114 | Children of Men | $2,180,299 | 6 | 1,886 | 2006 | United International Pictures | 
| 115 | Cándida | $2,175,947 | 7 | 1,890 | 2006 | 20th Century Fox International | 
| 116 | Thi Mai, rumbo a Vietnam | $2,174,896 | 9 | 1,892 | 2018 | TriPictures | 
| 117 | The Dancer and the Thief | $2,172,688 | 7 | 1,895 | 2009 | Notro Films | 
| 118 | Ong-Bak: The Thai Warrior | $2,170,811 | 6 | 1,896 | 2004 | Manga Entertainment | 
| 119 | Room | $2,165,418 | 7 | 1,899 | 2016 | Universal Pictures International (UPI) | 
| 120 | A Very Long Engagement | $2,161,087 | 6 | 1,900 | 2005 | Warner Bros. | 
| 121 | The Way | $2,150,273 | 7 | 1,645 | 2008 | Alta Films | 
| 122 | 127 Hours | $2,149,650 | 6 | 1,904 | 2011 | 20th Century Fox International | 
| 123 | Ozzy | $2,135,700 | 6 | 1,910 | 2016 | Walt Disney Pictures | 
| 124 | Phantom Thread | $2,133,420 | 6 | 1,911 | 2018 | Universal Pictures International (UPI) | 
| 125 | The Concert | $2,131,980 | 10 | 1,913 | 2010 | Vértigo Films | 
| 126 | Jarhead | $2,122,937 | 8 | 1,918 | 2006 | United International Pictures | 
| 127 | Of Gods and Men | $2,120,166 | 13 | 1,920 | 2011 | Golem Distribución | 
| 128 | Summer Rain | $2,119,424 | 7 | 1,921 | 2006 | 20th Century Fox International | 
| 129 | Daddy's Home | $2,114,036 | 6 | 1,923 | 2016 | Paramount Pictures International | 
| 130 | Tinker Bell and the Great Fairy Rescue | $2,094,543 | 10 | 1,933 | 2010 | Walt Disney Pictures | 
| 131 | Broken Flowers | $2,087,587 | 7 | 1,936 | 2005 | Vértigo Films | 
| 132 | Welcome to the South | $2,066,409 | 9 | 1,946 | 2011 | - | 
| 133 | Assault on Precinct 13 | $2,065,351 | 8 | 1,947 | 2005 | United International Pictures | 
| 134 | Carlitos and the Chance of a Lifetime | $2,064,565 | 10 | 1,948 | 2008 | 20th Century Fox International | 
| 135 | Capote | $2,058,336 | 9 | 1,952 | 2006 | Sony Pictures Releasing | 
| 136 | Spread | $2,052,392 | 11 | 1,955 | 2009 | Aurum Films | 
| 137 | Curse of the Golden Flower | $2,033,892 | 7 | 1,964 | 2007 | Sony Pictures Releasing | 
| 138 | The Cold Light of Day | $2,033,522 | 7 | 1,965 | 2012 | Aurum Films | 
| 139 | Silk | $2,029,874 | 9 | 1,966 | 2008 | TriPictures | 
| 140 | Bratz | $2,026,858 | 8 | 1,968 | 2007 | Aurum Films | 
| 141 | Christopher Robin | $2,022,599 | 8 | 1,970 | 2018 | Walt Disney Pictures | 
| 142 | The Count of Monte-Cristo | $2,018,515 | 10 | 1,973 | 2024 | Beta Fiction Spain | 
| 143 | El club de los suicidas | $2,017,741 | 7 | 1,974 | 2007 | Alta Films | 
| 144 | Kamikaze | $2,013,273 | 6 | 1,976 | 2014 | Warner Bros. | 
| 145 | Why Him? | $2,010,755 | 6 | 1,977 | 2017 | 20th Century Fox International | 
| 146 | The Teacher Who Promised the Sea | $2,008,800 | 6 | 1,979 | 2023 | Filmax | 
| 147 | Atasco en la nacional | $2,008,201 | 6 | 1,980 | 2007 | - | 
| 148 | The Age of Adaline | $2,006,494 | 6 | 1,983 | 2015 | Entertainment One | 
| 149 | The SpongeBob SquarePants Movie | $1,997,505 | 7 | 1,990 | 2005 | United International Pictures | 
| 150 | Paranormal Activity: The Marked Ones | $1,996,331 | 8 | 1,991 | 2014 | Paramount Pictures International | 
| 151 | The Fighter | $1,994,268 | 8 | 1,992 | 2011 | TriPictures | 
| 152 | Pitch Perfect 3 | $1,986,509 | 7 | 1,997 | 2017 | Universal Pictures International (UPI) | 
| 153 | Katmandú, un espejo en el cielo | $1,985,898 | 8 | 1,999 | 2012 | Alta Films | 
| 154 | Stand by Me Doraemon | $1,983,152 | 8 | 2,000 | 2014 | - | 
| 155 | Carol | $1,979,507 | 6 | 2,003 | 2016 | Vértigo Films | 
| 156 | Twice Born | $1,973,414 | 7 | 2,006 | 2013 | Alta Films | 
| 157 | Knocked Up | $1,969,909 | 7 | 2,007 | 2007 | Universal Pictures International (UPI) | 
| 158 | Nebraska | $1,966,445 | 6 | 2,013 | 2014 | Vértigo Films | 
| 159 | Holy Goalie | $1,958,544 | 8 | 2,016 | 2018 | DeAPlaneta | 
| 160 | Larry Crowne | $1,930,068 | 7 | 2,021 | 2011 | TriPictures | 
| 161 | Lady Bird | $1,928,001 | 6 | 2,022 | 2018 | Universal Pictures International (UPI) | 
| 162 | Space Chimps | $1,925,652 | 9 | 2,023 | 2008 | Aurum Films | 
| 163 | The Maidens' Conspiracy | $1,917,353 | 6 | 2,030 | 2006 | DeAPlaneta | 
| 164 | Brooklyn | $1,910,246 | 6 | 2,033 | 2016 | 20th Century Fox International | 
| 165 | Manual of Love | $1,907,699 | 12 | 2,037 | 2005 | Notro Films | 
| 166 | Mataharis | $1,904,293 | 6 | 2,039 | 2007 | 20th Century Fox International | 
| 167 | The Contract | $1,885,696 | 7 | 2,050 | 2008 | Filmax | 
| 168 | Emilia Pérez | $1,884,776 | 7 | 2,051 | 2024 | Wanda Visión S.A. | 
| 169 | The Class | $1,876,570 | 10 | 2,054 | 2009 | Golem Distribución | 
| 170 | Chaotic Ana | $1,871,286 | 9 | 2,059 | 2007 | 20th Century Fox International | 
| 171 | The Kite Runner | $1,870,588 | 11 | 2,060 | 2008 | Universal Pictures International (UPI) | 
| 172 | Easy Virtue | $1,870,010 | 10 | 2,061 | 2009 | DeAPlaneta | 
| 173 | That's My Boy | $1,869,356 | 6 | 2,063 | 2012 | Sony Pictures Releasing | 
| 174 | Killers | $1,865,795 | 6 | 2,065 | 2010 | DeAPlaneta | 
| 175 | Amour | $1,855,252 | 9 | 2,071 | 2013 | Golem Distribución | 
| 176 | The Notebook | $1,851,380 | 18 | 2,079 | 2004 | - | 
| 177 | Caramel | $1,848,875 | 11 | 2,082 | 2008 | Alta Films | 
| 178 | King Richard | $1,845,177 | 6 | 2,083 | 2022 | Warner Bros. | 
| 179 | My Life in Ruins | $1,842,519 | 7 | 2,085 | 2009 | Manga Entertainment | 
| 180 | Kubo and the Two Strings | $1,839,846 | 8 | 2,088 | 2016 | Universal Pictures International (UPI) | 
| 181 | Darkest Hour | $1,833,975 | 10 | 2,091 | 2018 | Universal Pictures International (UPI) | 
| 182 | Rolling to You 2018 Re-release | $1,833,279 | 8 | 2,093 | 2018 | A Contracorriente Films | 
| 183 | Burlesque | $1,831,895 | 6 | 2,094 | 2010 | Sony Pictures Releasing | 
| 184 | The Young Victoria | $1,812,249 | 7 | 2,108 | 2009 | Aurum Films | 
| 185 | I Heart Huckabees | $1,804,738 | 6 | 2,116 | 2005 | 20th Century Fox International | 
| 186 | Cellular | $1,804,281 | 6 | 2,117 | 2004 | TriPictures | 
| 187 | Luther | $1,798,095 | 8 | 2,120 | 2005 | Karma Films | 
| 188 | The Change-Up | $1,796,484 | 8 | 2,122 | 2011 | United International Pictures | 
| 189 | This Means War | $1,790,835 | 6 | 2,125 | 2012 | 20th Century Fox International | 
| 190 | The Hedgehog | $1,789,908 | 10 | 2,126 | 2009 | Alta Films | 
| 191 | Milk | $1,785,238 | 9 | 2,129 | 2009 | United International Pictures | 
| 192 | Yours, Mine & Ours | $1,778,306 | 8 | 2,132 | 2006 | Sony Pictures Releasing | 
| 193 | Inside Llewyn Davis | $1,772,335 | 9 | 2,134 | 2014 | Universal Pictures International (UPI) | 
| 194 | Two Lovers | $1,768,721 | 7 | 2,136 | 2010 | DeAPlaneta | 
| 195 | Donkey Xote | $1,761,676 | 8 | 2,137 | 2007 | Filmax | 
| 196 | The Misfits Club | $1,760,376 | 7 | 2,138 | 2014 | DeAPlaneta | 
| 197 | Shorts | $1,754,478 | 13 | 2,140 | 2009 | Warner Bros. | 
| 198 | La Vie En Rose | $1,754,341 | 11 | 2,141 | 2007 | Alta Films | 
| 199 | Ismael | $1,749,103 | 11 | 2,147 | 2013 | Sony Pictures Releasing | 
| 200 | The Princess Diaries 2: Royal Engagement | $1,746,397 | 8 | 2,150 | 2004 | Buena Vista International |