| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avengers: Infinity War | $3,708,812 | -53.9% | - | - | - | $15,908,355 | 3 | Walt Disney Pictures | false | false |
| 2 | - | The Trough | $311,748 | - | - | - | - | $311,748 | 1 | Edko Films | true | false |
| 3 | - | Secret Superstar | $180,979 | - | - | - | - | $1,560,450 | 5 | Edko Films | false | false |
| 4 | 2 | A Quiet Place | $131,287 | -26.8% | 33 | -3 | $3,978 | $2,129,733 | 4 | Paramount Pictures International | false | false |
| 5 | - | Love, Simon | $123,741 | - | 29 | - | $4,266 | $123,741 | 1 | 20th Century Fox International | true | false |
| 6 | - | Gonjiam: Haunted Asylum | $78,168 | - | - | - | - | $370,676 | 3 | N/A | false | false |
| 7 | - | Rampage | $75,129 | - | - | - | - | $2,363,519 | 4 | Warner Bros. | false | false |
| 8 | - | Tomorrow Is Another Day | $72,708 | - | - | - | - | $692,420 | 4 | N/A | false | false |
| 9 | - | Ready Player One | $70,376 | - | - | - | - | $5,849,906 | 6 | Warner Bros. | false | false |
| 10 | - | Isle of Dogs | $30,894 | - | - | - | - | $138,730 | 3 | 20th Century Fox International | false | false |
| 11 | 3 | Peter Rabbit | $5,028 | +6.1% | 6 | +2 | $838 | $1,408,261 | 6 | Sony Pictures Releasing | false | false |
