| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Apocalypto | $59,570 | -16.1% | 20 | - | $2,978 | $230,960 | 3 | 20th Century Fox International | false | false |
| 2 | - | Curse of the Golden Flower | $47,373 | - | 13 | - | $3,644 | $47,373 | 1 | Sony Pictures Releasing | true | false |
| 3 | 3 | Arthur and the Invisibles | $46,937 | -1% | 25 | - | $1,877 | $94,309 | 2 | Bazuca Films | false | false |
| 4 | 2 | Music and Lyrics | $45,129 | -25.1% | 27 | - | $1,671 | $105,308 | 2 | Warner Bros. | false | false |
| 5 | 5 | Night at the Museum | $37,047 | -7.1% | 34 | +1 | $1,089 | $1,851,474 | 10 | 20th Century Fox International | false | false |
| 6 | 4 | Borat | $31,178 | -32.3% | 8 | - | $3,897 | $77,212 | 2 | 20th Century Fox International | false | false |
| 7 | 7 | The Holiday | $28,277 | -11.2% | 23 | -4 | $1,229 | $257,765 | 5 | United International Pictures | false | false |
| 8 | 6 | Norbit | $26,800 | -17.8% | 22 | - | $1,218 | $106,177 | 3 | United International Pictures | false | false |
| 9 | 8 | Pan's Labyrinth | $23,748 | -11.4% | 6 | - | $3,958 | $189,513 | 5 | Warner Bros. | false | false |
| 10 | 9 | Blood Diamond | $22,087 | -15.1% | 24 | +1 | $920 | $455,421 | 8 | Warner Bros. | false | false |
| 11 | 10 | The Departed | $14,677 | -33.3% | 19 | +1 | $772 | $923,918 | 19 | Warner Bros. | false | false |
| 12 | 11 | Notes on a Scandal | $14,154 | -26% | 5 | - | $2,830 | $86,720 | 4 | 20th Century Fox International | false | false |
| 13 | 12 | Babel | $13,386 | -25.8% | 10 | -5 | $1,338 | $822,193 | 10 | United International Pictures | false | false |
| 14 | 13 | The Pursuit of Happyness | $13,213 | -21.6% | 11 | - | $1,201 | $219,196 | 7 | Sony Pictures Releasing | false | false |
| 15 | 14 | The Illusionist | $12,815 | -21.9% | 12 | -1 | $1,067 | $502,753 | 11 | Transeuropa | false | false |
| 16 | 16 | The Last King of Scotland | $9,908 | -1.4% | 4 | - | $2,477 | $96,172 | 6 | 20th Century Fox International | false | false |
| 17 | 15 | Letters from Iwo Jima | $8,030 | -22.9% | 7 | -1 | $1,147 | $140,460 | 6 | Warner Bros. | false | false |
| 18 | - | Me and You and Everyone We Know | $6,586 | - | 3 | - | $2,195 | $6,586 | 1 | Four Films | true | false |
| 19 | 19 | Flushed Away | $5,409 | +15.1% | 6 | - | $901 | $1,087,658 | 15 | United International Pictures | false | false |
| 20 | - | The Tiger and the Snow | $4,800 | - | 8 | - | $600 | $55,130 | 5 | Bazuca Films | false | false |
