| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Fast & Furious | $72,508,000 | $70,950,500 | -$1,557,500 | -2.1% | 3,461 | $72,508,000 | $70,950,500 | 1 | Universal Pictures | - |
| 2 | 2 | - | Monsters vs. Aliens | $33,510,000 | $32,609,165 | -$900,835 | -2.7% | 4,109 | $105,700,000 | $104,799,387 | 2 | DreamWorks | - |
| 3 | 3 | - | The Haunting in Connecticut | $9,550,000 | $9,481,647 | -$68,353 | -0.7% | 2,732 | $37,240,000 | $37,171,280 | 2 | Lionsgate Films | - |
| 4 | 4 | - | Knowing | $8,130,000 | $8,146,156 | +$16,156 | +0.2% | 3,323 | $58,204,000 | $58,219,770 | 3 | Summit Entertainment | - |
| 5 | 5 | - | I Love You, Man | $7,850,000 | $7,722,469 | -$127,531 | -1.6% | 2,829 | $49,287,000 | $49,159,559 | 3 | DreamWorks | - |
| 6 | 6 | - | Adventureland | $6,010,000 | $5,722,039 | -$287,961 | -4.8% | 1,862 | $6,010,000 | $5,722,039 | 1 | Miramax | - |
| 7 | 7 | - | Duplicity | $4,300,000 | $4,174,240 | -$125,760 | -2.9% | 2,522 | $32,376,000 | $32,250,215 | 3 | Universal Pictures | - |
| 8 | 8 | - | Race to Witch Mountain | $3,351,000 | $3,212,602 | -$138,398 | -4.1% | 2,825 | $58,388,000 | $58,249,111 | 4 | Walt Disney Studios Motion Pictures | - |
| 9 | 9 | - | 12 Rounds | $2,300,000 | $2,260,906 | -$39,094 | -1.7% | 2,331 | $9,022,000 | $8,982,767 | 2 | Twentieth Century Fox | - |
| 10 | 10 | - | Sunshine Cleaning | $1,879,000 | $1,807,164 | -$71,836 | -3.8% | 479 | $4,775,000 | $4,702,721 | 4 | Overture Films | - |
| 11 | 11 | - | Taken | $1,580,000 | $1,544,471 | -$35,529 | -2.2% | 1,355 | $139,452,000 | $139,416,323 | 10 | Twentieth Century Fox | - |
| 12 | 12 | - | The Last House on the Left | $1,312,000 | $1,259,325 | -$52,675 | -4% | 1,305 | $30,726,000 | $30,674,195 | 4 | Universal Pictures | - |
| 13 | 13 | - | Watchmen | $1,085,000 | $1,074,320 | -$10,680 | -1% | 1,103 | $105,357,000 | $105,346,566 | 5 | Warner Bros. | - |
| 14 | 14 | - | Slumdog Millionaire | $510,000 | $499,257 | -$10,743 | -2.1% | 498 | $140,255,000 | $140,244,722 | 21 | - | - |
| 15 | 15 | - | Madea Goes to Jail | $410,000 | $479,975 | +$69,975 | +17.1% | 619 | $89,800,000 | $89,869,224 | 7 | Lionsgate Films | - |
| 16 | 18 | +2 | Under the Sea 3D | $254,000 | $244,572 | -$9,428 | -3.7% | 43 | - | $4,720,450 | 8 | Warner Bros. | - |
| 17 | 20 | +3 | Hotel for Dogs | $205,000 | $194,542 | -$10,458 | -5.1% | 240 | $71,662,000 | $71,651,821 | 12 | DreamWorks | - |
| 18 | 22 | +4 | Sin Nombre | $194,000 | $184,380 | -$9,620 | -5% | 24 | $409,000 | $398,982 | 3 | Focus Features | - |
| 19 | 23 | +4 | Coraline | $193,000 | $178,148 | -$14,852 | -7.7% | 211 | $74,269,000 | $74,255,387 | 9 | Focus Features | - |
| 20 | 21 | +1 | The Reader | $192,000 | $192,085 | +$85 | <0.1% | 232 | $33,807,000 | $33,807,465 | 17 | The Weinstein Company | - |
| 21 | 27 | +6 | The Class | $140,000 | $129,928 | -$10,072 | -7.2% | 114 | $3,280,000 | $3,269,585 | 16 | Sony Pictures Classics | - |
| 22 | 25 | +3 | Push | $139,000 | $142,179 | +$3,179 | +2.3% | 214 | $31,328,000 | $31,331,232 | 9 | Summit Entertainment | - |
| 23 | 26 | +3 | The Curious Case of Benjamin Button | $131,000 | $131,342 | +$342 | +0.3% | 213 | $127,247,000 | $127,247,417 | 15 | Paramount Pictures | - |
| 24 | 29 | +5 | The Cross | $88,800 | $93,980 | +$5,180 | +5.8% | 127 | $491,000 | $496,009 | 2 | 8x Entertainment | - |
| 25 | 44 | +19 | Paris 36 | $72,200 | $44,690 | -$27,510 | -38.1% | 7 | $322,000 | $294,395 | 1 | Sony Pictures Classics | - |
| 26 | 36 | +10 | Sugar | $71,200 | $60,140 | -$11,060 | -15.5% | 11 | $71,200 | $60,140 | 1 | Sony Pictures Classics | - |
| 27 | 39 | +12 | Valentino: The Last Emperor | $57,600 | $56,783 | -$817 | -1.4% | 4 | $178,000 | $176,180 | 3 | Truly Indie | - |
| 28 | 42 | +14 | Doubt | $46,000 | $45,577 | -$423 | -0.9% | 77 | $33,423,000 | $33,422,556 | 17 | Miramax | - |
| 29 | 45 | +16 | Alien Trespass | $42,900 | $43,437 | +$537 | +1.3% | 40 | $42,900 | $43,437 | 1 | Roadside Attractions | - |
| 30 | 52 | +22 | Goodbye Solo | $32,800 | $30,395 | -$2,405 | -7.3% | 5 | $83,300 | $80,868 | 2 | Roadside Attractions | - |
| 31 | 54 | +23 | Wendy and Lucy | $29,100 | $26,212 | -$2,888 | -9.9% | 32 | $787,000 | $783,789 | 17 | Oscilloscope | - |
| 32 | 55 | +23 | Defiance | $25,000 | $23,635 | -$1,365 | -5.5% | 52 | $28,516,000 | $28,514,684 | 14 | Paramount Vantage | - |
| 33 | 60 | +27 | Fanboys | $17,500 | $16,695 | -$805 | -4.6% | 22 | $647,000 | $646,022 | 9 | The Weinstein Company | - |
| 34 | 64 | +30 | Milk | $12,000 | $12,981 | +$981 | +8.2% | 29 | $31,817,000 | $31,817,897 | 19 | Focus Features | - |
| 35 | 65 | +30 | Crossing Over | $11,100 | $12,038 | +$938 | +8.5% | 18 | $430,000 | $431,036 | 6 | The Weinstein Company | - |
| 36 | 68 | +32 | Gigantic | $10,500 | $10,294 | -$206 | -2% | 1 | $10,500 | $10,294 | 1 | First Independent Pictures | - |
| 37 | 75 | +38 | The Song of Sparrows | $9,300 | $7,863 | -$1,437 | -15.5% | 1 | $9,300 | $7,863 | 1 | Regent Releasing | - |
| 38 | 86 | +48 | Valkyrie | $4,000 | $3,541 | -$459 | -11.5% | 14 | $83,076,000 | $83,075,363 | 15 | United Artists | - |
| 39 | 92 | +53 | Mancora | $1,870 | $2,571 | +$701 | +37.5% | 2 | $18,500 | $19,169 | 3 | Maya Entertainment | - |
