| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Hitchhiker's Guide to the Galaxy | $21,700,000 | $21,103,203 | -$596,797 | -2.8% | 3,133 | $21,700,000 | $21,103,203 | 1 | Walt Disney Studios Motion Pictures | - |
| 2 | 2 | - | The Interpreter | $14,200,000 | $13,833,815 | -$366,185 | -2.6% | 2,764 | $43,600,000 | $43,152,385 | 2 | Universal Pictures | - |
| 3 | 3 | - | xXx: State of the Union | $13,700,000 | $12,712,272 | -$987,728 | -7.2% | 3,480 | $13,700,000 | $12,712,272 | 1 | Revolution Studios | - |
| 4 | 4 | - | The Amityville Horror | $8,100,000 | $7,862,157 | -$237,843 | -2.9% | 3,058 | $55,100,000 | $54,816,999 | 3 | Metro-Goldwyn-Mayer (MGM) | - |
| 5 | 5 | - | Sahara | $6,000,000 | $5,708,332 | -$291,668 | -4.9% | 3,112 | $57,200,000 | $56,885,831 | 4 | Paramount Pictures | - |
| 6 | 6 | - | A Lot Like Love | $5,200,000 | $5,084,727 | -$115,273 | -2.2% | 2,502 | $14,700,000 | $14,561,119 | 2 | Walt Disney Studios Motion Pictures | - |
| 7 | 7 | - | Kung Fu Hustle | $3,800,000 | - | - | - | 2,440 | $13,200,000 | - | 4 | Sony Pictures Classics | - |
| 8 | 8 | - | Fever Pitch | $3,800,000 | $3,532,813 | -$267,187 | -7% | 2,192 | $36,500,000 | $36,317,491 | 4 | Twentieth Century Fox | - |
| 9 | 9 | - | Robots | $2,700,000 | $2,269,605 | -$430,395 | -15.9% | 1,782 | $123,700,000 | $123,300,061 | 8 | Twentieth Century Fox | - |
| 10 | 10 | - | Guess Who | $2,200,000 | $2,151,446 | -$48,554 | -2.2% | 1,863 | $65,500,000 | $65,434,348 | 6 | Sony Pictures Releasing | - |
| 11 | 11 | - | Sin City | $2,000,000 | - | - | - | 1,665 | $70,600,000 | - | 5 | Dimension Films | - |
| 12 | 12 | - | The Pacifier | $1,400,000 | $1,351,787 | -$48,213 | -3.4% | 1,224 | $108,400,000 | $108,377,223 | 9 | Walt Disney Studios Motion Pictures | - |
| 13 | 15 | +2 | King's Ransom | $831,925 | - | - | - | 1,508 | $3,499,259 | - | 2 | New Line Cinema | - |
| 14 | 17 | +3 | The Upside of Anger | $600,022 | - | - | - | 816 | $17,717,325 | - | 8 | New Line Cinema | - |
| 15 | 19 | +4 | Enron: The Smartest Guys in the Room | $411,960 | - | - | - | 49 | $523,774 | - | 2 | Magnolia Pictures | - |
