| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inside Out | $594,867 | -36.8% | 158 | -21 | $3,764 | $2,911,275 | 3 | Walt Disney Pictures | false | false |
| 2 | 2 | Heaven on Earth 2015 Re-release | $433,311 | -32% | 173 | -87 | $2,504 | $1,461,081 | 2 | Svensk Filmindustri (SF) | false | false |
| 3 | - | Straight Outta Compton | $267,029 | - | 64 | - | $4,172 | $270,870 | 1 | United International Pictures | true | false |
| 4 | - | Vacation | $145,540 | - | 144 | - | $1,010 | $145,540 | 1 | 20th Century Fox International | true | false |
| 5 | 3 | Ingrid 2015 Re-release | $121,043 | -34% | 123 | +16 | $984 | $974,471 | 3 | N/A | false | false |
| 6 | 4 | Mission: Impossible - Rogue Nation | $100,732 | -27.3% | 47 | -4 | $2,143 | $3,034,216 | 7 | United International Pictures | false | false |
| 7 | 6 | Minions | $70,525 | -32.6% | 57 | -5 | $1,237 | $7,102,289 | 11 | United International Pictures | false | false |
| 8 | 8 | Curious George 3: Back to the Jungle | $63,045 | -20.8% | 80 | +6 | $788 | $406,662 | 5 | United International Pictures | false | false |
| 9 | 7 | Sinister 2 | $55,441 | -35.8% | 49 | -1 | $1,131 | $423,437 | 4 | Scanbox Entertainment | false | false |
| 10 | 5 | Hitman: Agent 47 | $45,156 | -57% | 47 | -29 | $960 | $424,148 | 3 | 20th Century Fox International | false | false |
| 11 | - | Ricki and the Flash | $45,133 | - | 44 | - | $1,025 | $45,133 | 1 | Sony Pictures Releasing | true | false |
| 12 | 11 | No Escape | $39,908 | -33.8% | 34 | -18 | $1,173 | $122,016 | 2 | Noble Entertainment | false | false |
| 13 | 9 | The Man from U.N.C.L.E. | $36,009 | -43.3% | 24 | -15 | $1,500 | $615,807 | 5 | 20th Century Fox International | false | false |
| 14 | 10 | Pixels | $28,736 | -52.9% | 27 | -18 | $1,064 | $658,822 | 5 | Sony Pictures Releasing | false | false |
| 15 | 13 | Trainwreck | $20,217 | -53.9% | 18 | -12 | $1,123 | $312,810 | 4 | United International Pictures | false | false |
| 16 | 12 | Southpaw | $19,984 | -55% | 23 | -14 | $868 | $496,294 | 6 | Scanbox Entertainment | false | false |
| 17 | 15 | Woman in Gold | $19,954 | -25% | 26 | -2 | $767 | $461,415 | 7 | Scanbox Entertainment | false | false |
| 18 | 14 | Ant-Man | $14,578 | -49.6% | 10 | -8 | $1,457 | $2,138,644 | 8 | Walt Disney Pictures | false | false |
| 19 | 17 | Tangerines | $13,767 | -12.9% | 16 | -4 | $860 | $45,859 | 2 | N/A | false | false |
| 20 | 16 | Paper Towns | $11,437 | -49.2% | 11 | -7 | $1,039 | $1,170,446 | 8 | 20th Century Fox International | false | false |
| 21 | 21 | Love & Mercy | $1,403 | -45% | 6 | - | $233 | $44,805 | 5 | Sony Pictures Releasing | false | false |
