| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | This Means War | $648,276 | - | 101 | - | $6,418 | $763,585 | 1 | Warner Bros. | true | false |
| 2 | - | Safe House | $612,176 | - | 55 | - | $11,130 | $644,506 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 1 | The Muppets | $578,753 | +49% | 145 | - | $3,991 | $1,957,654 | 3 | Walt Disney Pictures | false | false |
| 4 | 6 | Cool Kids Don't Cry | $431,151 | +81.4% | 105 | +2 | $4,106 | $1,052,965 | 2 | N/A | false | false |
| 5 | 3 | Journey 2: The Mysterious Island | $377,298 | +21.3% | 83 | - | $4,545 | $919,255 | 2 | Warner Bros. | false | false |
| 6 | - | Fairytale Tree the Movie | $288,126 | - | 106 | - | $2,718 | $453,080 | 1 | N/A | true | false |
| 7 | 2 | The Descendants | $278,152 | -15.8% | 61 | +3 | $4,559 | $1,784,833 | 4 | Warner Bros. | false | false |
| 8 | 5 | Hugo | $265,863 | +0.2% | 54 | +2 | $4,923 | $717,074 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 13 | Tony 10 | $233,606 | +143.5% | 104 | - | $2,246 | $531,450 | 2 | N/A | false | false |
| 10 | - | The Woman in Black | $207,787 | - | 50 | - | $4,155 | $269,331 | 1 | Dutch FilmWorks (DFW) | true | false |
| 11 | 4 | Ghost Rider: Spirit of Vengeance | $173,653 | -35.3% | 54 | +1 | $3,215 | $558,382 | 2 | Entertainment One | false | false |
| 12 | 16 | Alvin and the Chipmunks: Chipwrecked | $131,014 | +105% | 85 | -7 | $1,541 | $6,704,690 | 11 | Warner Bros. | false | false |
| 13 | 9 | War Horse | $114,139 | -23.7% | 90 | -8 | $1,268 | $1,016,918 | 4 | Walt Disney Pictures | false | false |
| 14 | 10 | Süskind | $108,112 | -21.6% | 89 | -14 | $1,214 | $1,825,739 | 6 | N/A | false | false |
| 15 | 11 | Kill Zombie! | $95,692 | -24.6% | 60 | -1 | $1,594 | $302,777 | 2 | A-Film Distribution | false | false |
| 16 | 14 | The Iron Lady | $93,573 | -2.3% | 50 | -4 | $1,871 | $1,712,371 | 7 | N/A | false | false |
| 17 | 7 | The Devil Inside | $92,876 | -40.9% | 34 | -1 | $2,731 | $761,602 | 3 | Universal Pictures International (UPI) | false | false |
| 18 | 8 | The Girl with the Dragon Tattoo | $92,515 | -38.6% | 67 | -24 | $1,380 | $2,501,036 | 6 | Sony Pictures Releasing | false | false |
| 19 | 18 | Puss in Boots | $86,265 | +96.8% | 55 | -15 | $1,568 | $5,990,977 | 12 | Universal Pictures International (UPI) | false | false |
| 20 | 20 | Shame | $77,450 | +765.1% | 21 | - | $3,688 | $411,820 | 3 | N/A | false | false |
