| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Sherlock Holmes: A Game of Shadows | $621,303 | -31.2% | 130 | -1 | $4,779 | $1,948,321 | 2 | Warner Bros. | false | false |
| 2 | 2 | The Muppets | $487,471 | -20.9% | 103 | +5 | $4,732 | $1,481,671 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | Puss in Boots | $406,899 | -24.2% | 114 | -26 | $3,569 | $10,540,267 | 7 | United International Pictures | false | false |
| 4 | - | Tower Heist | $328,523 | - | 50 | - | $6,570 | $328,523 | 1 | Universal Pictures International (UPI) | true | false |
| 5 | 4 | Mission: Impossible - Ghost Protocol | $287,802 | -38.6% | 114 | -22 | $2,524 | $2,337,948 | 3 | Paramount Pictures International | false | false |
| 6 | 6 | Alvin and the Chipmunks: Chipwrecked | $235,510 | -10% | 86 | +2 | $2,738 | $1,307,436 | 3 | 20th Century Fox International | false | false |
| 7 | 5 | The Darkest Hour | $227,952 | -27.9% | 64 | -9 | $3,561 | $696,165 | 2 | 20th Century Fox International | false | false |
| 8 | - | The Ides of March | $193,941 | - | 39 | - | $4,972 | $193,941 | 1 | Distribution Company | true | false |
| 9 | - | The Girl with the Dragon Tattoo | $193,505 | - | 50 | - | $3,870 | $193,505 | 1 | Sony Pictures Releasing | true | false |
| 10 | 7 | The Adventures of Tintin | $105,089 | -50.3% | 80 | -63 | $1,313 | $1,286,567 | 3 | Sony Pictures Releasing | false | false |
| 11 | 8 | The Help | $53,500 | -36.2% | 21 | +3 | $2,547 | $179,486 | 2 | Walt Disney Pictures | false | false |
| 12 | 10 | Shark Night | $31,526 | -23.3% | 13 | -2 | $2,425 | $858,632 | 5 | Walt Disney Pictures | false | false |
| 13 | 9 | 50/50 | $20,225 | -58.6% | 16 | -3 | $1,264 | $224,673 | 3 | Distribution Company | false | false |
| 14 | 11 | Cave of Forgotten Dreams | $9,670 | -32.3% | 5 | - | $1,934 | $114,880 | 4 | N/A | false | false |
| 15 | 12 | We Bought a Zoo | $8,851 | -30.2% | 19 | -6 | $465 | $265,623 | 4 | 20th Century Fox International | false | false |
| 16 | 13 | The Twilight Saga: Breaking Dawn - Part 1 | $8,770 | -19.5% | 16 | +6 | $548 | $5,386,420 | 10 | Alfa Films | false | false |
| 17 | - | Domingo de ramos | $5,745 | - | 4 | - | $1,436 | $6,676 | 1 | Primer Plano Film Group | true | false |
| 18 | 15 | Moneyball | $4,149 | -53.6% | 10 | -4 | $414 | $508,641 | 6 | Sony Pictures Releasing | false | false |
| 19 | 14 | New Year's Eve | $3,934 | -62.2% | 5 | -6 | $786 | $1,000,348 | 7 | Warner Bros. | false | false |
| 20 | 17 | O'Horten 2012 Re-release | $2,622 | -36.9% | 4 | - | $655 | $10,037 | 2 | N/A | false | false |
| 21 | 18 | The First Beautiful Thing 2011 Re-release | $2,568 | -30% | 2 | -1 | $1,284 | $227,433 | 11 | CDI Films | false | false |
| 22 | 23 | The Skin I Live In | $2,420 | +15.3% | 3 | - | $806 | $785,488 | 12 | N/A | false | false |
| 23 | 21 | Paranormal Activity 3 | $1,823 | -30.1% | 2 | -1 | $911 | $3,339,179 | 14 | Paramount Pictures International | false | false |
| 24 | 20 | A Film with Me in It 2011 Re-release | $1,727 | -35.8% | 3 | -2 | $575 | $50,051 | 6 | Impacto Cine | false | false |
| 25 | 22 | Love Songs 2011 Re-release | $1,425 | -37.6% | 2 | -2 | $712 | $24,240 | 5 | N/A | false | false |
| 26 | 26 | Alamar | $1,379 | +5% | 2 | - | $689 | $32,204 | 7 | N/A | false | false |
| 27 | 25 | Norberto's Deadline 2012 Re-release | $1,330 | -8.5% | 3 | +2 | $443 | $7,431 | 3 | Primer Plano Film Group | false | false |
| 28 | 42 | Arthur Christmas | $1,020 | +2,450% | 3 | +2 | $340 | $738,955 | 8 | Sony Pictures Releasing | false | false |
| 29 | 24 | Las Acacias | $972 | -36.6% | 2 | +1 | $486 | $106,119 | 9 | Distribution Company | false | false |
| 30 | 16 | In Time | $956 | -83.5% | 3 | -9 | $318 | $832,778 | 8 | 20th Century Fox International | false | false |
| 31 | 19 | Seeking Justice | $891 | -69% | 1 | -4 | $891 | $705,134 | 9 | N/A | false | false |
| 32 | 30 | La mala verdad | $580 | -11.7% | 1 | - | $580 | $51,791 | 8 | Primer Plano Film Group | false | false |
| 33 | 29 | Verdades verdaderas, la vida de Estela | $536 | -30.7% | 1 | - | $536 | $91,874 | 10 | Primer Plano Film Group | false | false |
| 34 | 27 | Water and Salt | $476 | -53.6% | 1 | - | $476 | $1,875 | 2 | Primer Plano Film Group | false | false |
| 35 | 33 | We Have a Pope | $233 | -6.8% | 1 | - | $233 | $642,498 | 20 | Alfa Films | false | false |
| 36 | 32 | Midnight in Paris | $215 | -17.9% | 1 | - | $215 | $3,798,523 | 30 | N/A | false | false |
| 37 | 35 | Clubbing | $199 | -15.3% | 1 | - | $199 | $101,542 | 12 | N/A | false | false |
| 38 | 34 | The Bell | $171 | -31.3% | 1 | - | $171 | $13,401 | 6 | N/A | false | false |
| 39 | 39 | Real Steel | $157 | +12.1% | 1 | - | $157 | $3,408,178 | 16 | Walt Disney Pictures | false | false |
| 40 | 38 | Sidewalls | $136 | -13.4% | 2 | +1 | $68 | $308,546 | 16 | Primer Plano Film Group | false | false |
| 41 | 40 | The Tree of Life | $81 | -6.9% | 1 | - | $81 | $595,294 | 17 | N/A | false | false |
| 42 | 36 | Un mundo seguro | $20 | -89.8% | 1 | - | $20 | $3,718 | 3 | Primer Plano Film Group | false | false |
