| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Smurfs | $14,684 | -22.3% | 11 | -3 | $1,334 | $491,432 | 8 | Sony Pictures Releasing | false | false |
| 2 | - | Friends with Benefits | $11,793 | - | 7 | - | $1,684 | $13,293 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | Johnny English Reborn | $9,469 | -38.5% | 8 | - | $1,183 | $71,744 | 3 | United International Pictures | false | false |
| 4 | 3 | Crazy, Stupid, Love. | $6,269 | -49.1% | 7 | - | $895 | $27,669 | 2 | Warner Bros. | false | false |
| 5 | 5 | Final Destination 5 | $4,487 | -31.2% | 10 | - | $448 | $66,149 | 5 | Warner Bros. | false | false |
| 6 | 6 | Cars 2 | $3,679 | -42.1% | 11 | - | $334 | $39,741 | 4 | Walt Disney Pictures | false | false |
| 7 | 4 | Bad Teacher | $3,381 | -50.4% | 6 | -1 | $563 | $47,547 | 4 | Sony Pictures Releasing | false | false |
| 8 | 8 | Mr. Popper's Penguins | $2,442 | +38.7% | 8 | - | $305 | $48,265 | 6 | 20th Century Fox International | false | false |
| 9 | 7 | Horrible Bosses | $1,677 | -51.3% | 7 | - | $239 | $78,681 | 7 | Warner Bros. | false | false |
| 10 | 11 | Harry Potter and the Deathly Hallows: Part 2 | $832 | -9.5% | 12 | - | $69 | $272,057 | 12 | Warner Bros. | false | false |
| 11 | 9 | Rise of the Planet of the Apes | $803 | -43.6% | 6 | - | $133 | $69,946 | 9 | 20th Century Fox International | false | false |
| 12 | 10 | Zookeeper | $571 | -43.9% | 7 | -3 | $81 | $29,271 | 6 | Sony Pictures Releasing | false | false |
| 13 | 12 | Larry Crowne | $330 | -55.8% | 4 | - | $82 | $11,141 | 5 | N/A | false | false |
| 14 | 16 | Kung Fu Panda 2 | $247 | +12.8% | 11 | - | $22 | $176,951 | 18 | United International Pictures | false | false |
| 15 | 13 | The Hangover Part II | $222 | -66.4% | 7 | - | $31 | $338,231 | 19 | Warner Bros. | false | false |
| 16 | 17 | The Ages of Love | $132 | +9.1% | 2 | - | $66 | $32,263 | 19 | N/A | false | false |
| 17 | 15 | Cowboys & Aliens | $27 | -88.1% | 5 | - | $5 | $19,682 | 8 | United International Pictures | false | false |
| 18 | 18 | Captain America: The First Avenger | $25 | -77.1% | 4 | - | $6 | $32,734 | 10 | United International Pictures | false | false |
