| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Smurfs | $18,890 | -19.7% | 14 | +1 | $1,349 | $471,388 | 7 | Sony Pictures Releasing | false | false |
| 2 | 2 | Johnny English Reborn | $15,393 | -33% | 8 | - | $1,924 | $59,327 | 2 | United International Pictures | false | false |
| 3 | - | Crazy, Stupid, Love. | $12,314 | - | 7 | - | $1,759 | $15,230 | 1 | Warner Bros. | true | false |
| 4 | 3 | Bad Teacher | $6,822 | -31.8% | 7 | +1 | $974 | $42,082 | 3 | Sony Pictures Releasing | false | false |
| 5 | 5 | Final Destination 5 | $6,518 | -11.5% | 10 | - | $651 | $63,532 | 4 | Warner Bros. | false | false |
| 6 | 4 | Cars 2 | $6,358 | -34.9% | 11 | - | $578 | $37,910 | 3 | Walt Disney Pictures | false | false |
| 7 | 6 | Horrible Bosses | $3,443 | -17.3% | 7 | - | $491 | $82,091 | 6 | Warner Bros. | false | false |
| 8 | 7 | Mr. Popper's Penguins | $1,761 | -42.3% | 8 | - | $220 | $49,748 | 5 | 20th Century Fox International | false | false |
| 9 | 8 | Rise of the Planet of the Apes | $1,424 | -34.6% | 6 | - | $237 | $74,657 | 8 | 20th Century Fox International | false | false |
| 10 | 10 | Zookeeper | $1,017 | -3.5% | 10 | - | $101 | $28,347 | 5 | Sony Pictures Releasing | false | false |
| 11 | 9 | Harry Potter and the Deathly Hallows: Part 2 | $919 | -23.9% | 12 | - | $76 | $296,328 | 11 | Warner Bros. | false | false |
| 12 | 11 | Larry Crowne | $747 | -21.1% | 4 | - | $186 | $11,324 | 4 | N/A | false | false |
| 13 | 12 | The Hangover Part II | $660 | -6.4% | 7 | - | $94 | $337,824 | 18 | Warner Bros. | false | false |
| 14 | 13 | Green Lantern | $247 | -13% | 7 | - | $35 | $21,076 | 8 | Warner Bros. | false | false |
| 15 | 15 | Cowboys & Aliens | $227 | +18.8% | 5 | - | $45 | $19,586 | 7 | United International Pictures | false | false |
| 16 | 16 | Kung Fu Panda 2 | $219 | +32.7% | 11 | - | $19 | $193,756 | 17 | United International Pictures | false | false |
| 17 | 20 | The Ages of Love | $121 | +77.9% | 2 | - | $60 | $35,123 | 18 | N/A | false | false |
| 18 | 19 | Captain America: The First Avenger | $109 | +45.3% | 4 | - | $27 | $32,672 | 9 | United International Pictures | false | false |
| 19 | 14 | Winnie the Pooh | $60 | -68.8% | 7 | - | $8 | $22,105 | 12 | Walt Disney Pictures | false | false |
| 20 | 21 | Something Borrowed | $44 | -12% | 3 | - | $14 | $25,563 | 20 | N/A | false | false |
| 21 | 17 | Transformers: Dark of the Moon | $28 | -75.7% | 11 | - | $2 | $124,347 | 13 | United International Pictures | false | false |
